UDC 544.77.051

  • Ahmet Beyatli University of Health Sciences Email:
  • Shalima Shawuti Istanbul University, Faculty of Medicine Email:
  • İshak Afşin Kariper Erciyes University Email:
  • Isık Neslişah Korkut Istanbul University, Faculty of Medicine Email:
  • Zerrin Aktaş Istanbul University, Faculty of Medicine Email:
  • Erdem Kuruca Serap Istanbul University, Faculty of Medicine Email:


The goal of this research was to make Ag and Fe nanoparticles out of Rosa canina (RC) fruit extract and test their anticancer and antibacterial activity against human breast cancer cell line and different human pathogenic bacteria. Green synthesis used to synthesize silver (RC-AgNPs) and iron (RC-FeNPs) nanoparticles from the fruit aqueous extract of RC. The formation of nanoparticles was characterized by scanning electron microscopy with energy dispersive x-ray spectroscopy, UV-Vis and Fourier transform infrared (FTIR) spectroscopy. RC-AgNPs formation was also investigated the surface charge, particle size, and distribution using zetasizer analysis by DLS. Both nanoparticles showed different levels of cytotoxicity against AGS (human gastric adenocarcinoma) cell line, while RC-AgNPs was not cytotoxic to HUVEC (Human umbilical vein endothelial) cell line in same concentrations which expressing selective anticancer effect. RC-AgNPs showed antibacterial activity against multidrug pathogens, but RC-FeNPs failed to show such activity. The current study's findings point to the prospective applications of green synthesized RC-AgNPs and RC-FeNPs in the biomedical, pharmaceutical, and nanotechnology industries.


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Биографии авторов

Ahmet Beyatli, University of Health Sciences

Assistant Professor of the Department of medicinal and aromatic plants

Shalima Shawuti, Istanbul University, Faculty of Medicine

Postdoctoral fellow of the Department of Physiology

İshak Afşin Kariper, Erciyes University

ssociate Professor of the Faculty of Education

Isık Neslişah Korkut, Istanbul University, Faculty of Medicine

Graduate Student of the Department of Physiology

Zerrin Aktaş, Istanbul University, Faculty of Medicine

Professor of the Department of Medical Microbiology

Erdem Kuruca Serap, Istanbul University, Faculty of Medicine

Professor of the Department of Physiology


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Как цитировать
1. Beyatli A., Shawuti S., Kariper İshak A., Korkut I. N., Aktaş Z., Serap E. K. BIOSYNTHESIS, CHARACTERIZATION, ANTIMICROBIAL AND ANTICANCER PROPERTIES OF SILVER AND IRON NANOPARTICLES FROM ROSA CANINA L. EXTRACT // Химия растительного сырья, 2023. № 4. С. 325-334. URL:
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