THE COMPONENT COMPOSITION OF THE TRAGOPOGON ORIENTALIS VOLATILE CONSTITUENTS AND ITS BIOLOGICAL ACTIVITY

  • Yerlan Melsuly Suleimen Institute of Applied Chemistry, L.N. Gumilyov Eurasian National University
  • Gulsana Galimzhankyzy Sissengaliyeva Institute of Applied Chemistry, L.N. Gumilyov Eurasian National University
  • Margarita Yulaevna Ishmuratova E.A. Buketov Karaganda State University
  • Roza Ilemisovna Jalmakhanbetova Institute of Applied Chemistry, L.N. Gumilyov Eurasian National University; Kazak University of Technology and Business

Аннотация

The purpose of this study is the chemical investigation of the composition of Tragopogon orientalis volatile constituents (VC) and studying of its biological activity.

This article presents the results of research on the study of the chemical composition of species Tragopogon, as well as data of antiradical and cytotoxic activity. To study the dried and crushed aboveground part of the plant (leaves, flowers and stems) was taken. The raw material was collected in the flowering phase, growing in Northern Kazakstan. The VC was isolated from the plant of Tragopogon orientalis by hydrodistillation method on the Clevenger type  apparatus. The chemical composition of the VC was determined by GC/MS.

The cytotoxic activity of the VC was determined by the survival rate of sea shrimp Artemia salina. VC of T. orientalis in all studied concentrations (1–10 mg ml-1) exhibit acute lethal toxicity - all larvae die. Antiradical activity was determined by the method of colorimetry of free radicals (DPPH). The experimental results showed that the VC of T. orientalis at all tested concentrations (0.1–1.0 mg ml-1) exhibit low antiradical activity compared with the butylhydroxyanisole standard drug.

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Биографии авторов

Yerlan Melsuly Suleimen, Institute of Applied Chemistry, L.N. Gumilyov Eurasian National University

Candidate of Chem. Sciences, PhD, Director of the Institute of Applied Chemistry, Professor of Chemistry Department of L.N. Gumilev

Margarita Yulaevna Ishmuratova, E.A. Buketov Karaganda State University

Candidate of biological Sciences, Professor of botany Department of Karaganda state University

Roza Ilemisovna Jalmakhanbetova, Institute of Applied Chemistry, L.N. Gumilyov Eurasian National University; Kazak University of Technology and Business

Кафедра "Химия, химическая технология и экология", ассоциированный профессор, доктор химических наук

Литература

Sampietro D.A., Lizarraga E.F., Ibatayev Zh.A., Omarova A.B., Suleimen Ye.M., Catalán C.A.N. Natural Product Research: Formerly Natural Product Letters, 2016, vol. 30, pp. 1950–1955. DOI: 10.1080/14786419.2015.1091453.

Suleimen Ye.М., Ibatayev Zh.А., Iskakova Zh.B., Ishmuratova М.Yu. Chem. Nat. Compd., 2016, vol. 52, no. 1, pp. 171–172. DOI: 10.1007/s10600-016-1583-x.

Suleimen Ye.M., Ibataev Zh.A., Iskakova Zh.B., Ishmuratova M.Yu., Ross S.A., Martins C.H.G. Chem. Nat. Compd., 2016, vol. 52, no. 1, pp. 173–175. DOI: 10.1007/s10600-016-1584-9.

Kirillov V., Stikhareva T., Suleimen Ye., Serafimovich M., Kabanova S., Mukanov B. Natural Product Research: Formerly Natural Product Letters, 2016, vol. 31, pp. 117–123. DOI: 10.1080/14786419.2016.1214832.

Sampietro D.A., de los A. Gomez A., Jimenez C.M., Lizarraga E.F., Ibatayev Zh.A., Suleimen Ye.M., Catalán C.A. Natural Product Research: Formerly Natural Product Letters., 2017, vol. 31, pp. 1464–1467. DOI: 10.1080/14786419.2016.1258560.

Suleimen E.M., Myrzagaliyeva A.B., Ibatayev Zh.A., Iskakova Zh.B., Samarkhanov T.N., Medeubayeva B.Z. Khimiya Rastitel'nogo Syr'ya, 2016, no. 4, pp. 83–88. DOI: 10.14258/jcprm.2016041340.

Suleimen E.M., Gorovoi P.G., Dudkin R.V., Ibataev Zh.A., Ross S.A. Chem. Nat. Compd., 2017, vol. 53, no. 2, pp. 388–389. DOI: 10.1007/s10600-017-2001-8.

Zhunusova M.A., Suleimen Ye.M., Iskakova Zh.B., Ishmuratova M.Yu., Abdullabekova R.M. Chem. Nat. Compd., 2017, vol. 53, no. 4, pp. 775–777. DOI: 10.1007/s10600-017-2118-9.

Suleimen Ye.M., Zhanzhaxina А.Sh., Sissengalieva G.G., Iskakova Zh.B., Ishmuratova М.Yu. Chem. Nat. Compd., 2018, vol. 54, no. 3, pp. 595–596. DOI: 10.1007/s10600-018-2420-1.

Suleimen Ye.M., Iskakova Zh.B., Dudkin R.V., Gorovoi P.G. Chem. Nat. Compd., 2018, no. 3, pp. 507–508. DOI: 10.1007/s10600-018-2421-0.

Pavlov N.V. Flora Kazakhstana. [Flora of Kazakhstan]. Alma-Ata, 1966, 450 p. (in Russ.).

Kamyshev N.S. Flora Tsentral'nogo Chernozem'ya i yeye analiz. [Flora of the Central Black Earth Region and its anal-ysis]. Voronezh, 1978, 116 p. (in Russ.).

Budantseva A.L., Lesiovskaya E.E. Dikorastushchiye poleznyye rasteniya Rossii. [Wild useful plants of Russia]. St. Pe-tersburg, 2001, 130 p. (in Russ.).

Chuhno V., Rozhko N. Lekarstvennyye rasteniya. Illyustrirovannyy entsiklopedicheskiy slovar'. [Medicinal plants. Il-lustrative encyclopedic dictionary]. Moscow, 2007, 768 p. (in Russ.).

Bubenchikova V.N., Trembalya Ya.S., Prokhorova S.A. Nauchnyye vedomosti Belgorodskogo gosudarstvennogo uni-versiteta. Seriya: Yestestvennyye nauki, 2011, vol. 104, no. 15-2, pp. 82–88. (in Russ.).

Bubenchikova V.N., Prokhorova S.A. Vestnik novykh meditsinskikh tekhnologiy, 2011, vol. 18, no. 3, pp. 272–273. (in Russ.).

Gosudarstvennaya farmakopeya SSSR. [State Pharmacopoeia of the USSR]. Moscow, 1990, vol. 2, 400 p. (in Russ.).

Suleimenov Ye.M. Chem. Nat. Compd., 2009, vol. 45, no. 5, pp. 710–711. DOI: 10.1007/s10600-009-9423-x.

Sawant O., Kadam V.J., Ghosh R. Journal of Herbal Medicine and Toxicology, 2009, vol. 3, pp. 39–44.

Sisengalieva G.G., Suleimen Ye.M., Ishmuratova M.Yu., Iskakova Zh.B., Van Hecke K. Chem. Nat. Compd., 2015, vol. 51, no. 3, pp. 544–547. DOI: 10.1007/s10600-015-1337-1.

Опубликован
2019-04-09
Как цитировать
1. Suleimen Y. M., Sissengaliyeva G. G., Ishmuratova M. Y., Jalmakhanbetova R. I. THE COMPONENT COMPOSITION OF THE TRAGOPOGON ORIENTALIS VOLATILE CONSTITUENTS AND ITS BIOLOGICAL ACTIVITY // Химия растительного сырья, 2019. № 3. С. 103-108. URL: http://journal.asu.ru/cw/article/view/4859.
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Низкомолекулярные соединения