RADIOPROTECTIVE EFFECT OF RAMSON (ÁLLIUM URSÍNUM L.) AND BOG BILBERRY (VACCINIUM ULIGINOSUM L.)

  • Valery E. Tarabanko Institute of Chemistry and Chemical Technology SB RAS, Akademgorodok, 50/24, Krasnoyarsk, 660036
  • Evgeniy T. Rodionov LTD «Dikorosy», Zatonskaya St., 29A, bl. 12, Krasnoyarsk, 660052
  • Ludmila B. Toporkova Scientific Research Institute of Clinical immunology, Siberian Branch, Russian Academy of Medical Sciences, Yadrintsevskaya, 14, Novosibirsk, 630099
  • Muench Sergey IOANESSI GmbH, Innovationspark, Marie-Curie-Str. 8, 51377 Leverkusen
  • Irina A. Orlovskaya LTD «Dikorosy», Zatonskaya St., 29A, bl. 12, Krasnoyarsk, 660052
Ключевые слова: Radioprotector, ramson, Állium Ursínum, bog bilberry, Vaccinium uliginosum, mice, X-ray

Аннотация

Radioprotective properties of the products produced from ramson (Állium Ursínum L.) and bog bilberry (Vaccinium uliginosum L.) were studied. Mice fed with the dried ramson and the bog bilberry extract were irradiated by X-rays (8 Gray). Strong radioprotective effect of these plant products was registered. The ramson demonstrated more radioprotective effect in comparison with bog bilberryextract. The radioprotective effect of Allium is probably determined by cysteine sulfoxides and their degradation products, such as diallyl disulfide and allyl methyl disulfide. The radioprotectors studied increase minimum parameters of erythropoiesis (red blood cell number and hematocrit) by a factor 1,5. Rapid recovery of the parameter of the platelets number of peripheral blood in all groups in comparison with control was registered. The survival ofmice fed with the dried ramson and the bog bilberry extract increased up to 60 and 53%, correspondingly, in comparison with 6,7%in the control group. These substances do not have side effects and contraindications and may be considered as a promising radioprotectors.

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Биографии авторов

Valery E. Tarabanko, Institute of Chemistry and Chemical Technology SB RAS, Akademgorodok, 50/24, Krasnoyarsk, 660036
the head of laboratory for biomass conversion, professor
Evgeniy T. Rodionov, LTD «Dikorosy», Zatonskaya St., 29A, bl. 12, Krasnoyarsk, 660052
General Director of «Dal-Ekspress» Association
Ludmila B. Toporkova, Scientific Research Institute of Clinical immunology, Siberian Branch, Russian Academy of Medical Sciences, Yadrintsevskaya, 14, Novosibirsk, 630099
Senior researcher of laboratory for immunobiology of stem cell, Ph.D
Muench Sergey, IOANESSI GmbH, Innovationspark, Marie-Curie-Str. 8, 51377 Leverkusen
Director of IOANESSI GmbH
Irina A. Orlovskaya, LTD «Dikorosy», Zatonskaya St., 29A, bl. 12, Krasnoyarsk, 660052
the head of laboratory for immunobiology of stem cell, Ph.D

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Опубликован
2015-05-25
Как цитировать
1. Tarabanko V. E., Rodionov E. T., Toporkova L. B., Sergey M., Orlovskaya I. A. RADIOPROTECTIVE EFFECT OF RAMSON (ÁLLIUM URSÍNUM L.) AND BOG BILBERRY (VACCINIUM ULIGINOSUM L.) // Химия растительного сырья, 2015. № 2. С. 253-256. URL: http://journal.asu.ru/cw/article/view/585.
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