ELEMENTAL COMPOSITION OF CHAGA MUSHROOM (INONOTUS OBLIQUUS)
UDC 582.284.3: 543.4.5
Abstract
Birch chaga Inonotus obliquus is used as a component of many medicines. This is due to the versatile therapeutic effect associated with the content of a large number of biologically active substances of inorganic, organometallic and organic nature, a high content of macro- and microelements both in a free state and in the form of chelate complexes. To establish the qualitative and quantitative elemental composition of birch chaga, highly sensitive physicochemical methods of analysis were used, such as atomic emission spectroscopy (AES), inductively coupled plasma mass spectrometry (ICP-MS), and neutron activation analysis (NAA). The scientific novelty of this study lies in the conduct of a complex physicochemical elemental layer-by-layer analysis of chaga, the analogs of which have not been found in the available literature. The analyzed samples of birch chaga layers contain the following elements: K, Na, Mg, Ca, Zn, Mn, Cu, Fe, Mo, Co, Cr, P, Br, Se, V, Al, Ba, Li, Ag, Au, Rb, Cs, As, Sb, B, Sr, Pb, Ni, Ti, Be, Ta, U, Th, Sc; the concentration of elements is highest in the outer layer of the fungus. It is noted that the content of both biogenic elements (K, Co, Mn) and potentially toxic (Ag, Br, Rb) is significantly higher than the corresponding clarkes in bios. Differences in the content of elements correlate with modern biochemical concepts of the composition of chaga, and in most cases also correlate with the values of clarkes in bios. The value of the detected toxicant elements does not exceed the MPC.
Downloads
Metrics
References
Shashkina M.Ya., Shashkin P.N., Sergeyev A.V. Khimiko-farmatsevticheskiy zhurnal, 2006, vol. 40, no. 10, pp. 37–44. (in Russ.).
Shashkina M.YA. Shashkin P.N., Sergeyev A.V. Rossiyskiy bioterapevticheskiy zhur-nal: Teoreticheskiy i nauchno-prakticheskiy zhurnal, 2005, vol. 4, no. 4, pp. 59–72. (in Russ.).
Karomatov I.Dzh., Murodova M.M. Biologiya i integrativnaya meditsina, 2017, no. 2, pp. 164–179. (in Russ.).
Zmitrovich I.V., Denisova N.P., Balandaykin M.E. i dr. Formuly farmatsii, 2020, vol. 2, no. 2, pp. 84–93. DOI: 10.17816/phf34803. (in Russ.).
Sysoyeva M.A. Vysokodispersnyye kolloidnyye sistemy i melaniny chagi: monografiya. [Highly dispersed colloidal systems and chaga melanins: monograph]. Kazan', 2013, 228 p. DOI: 10.1007/s11094-017-1601-8. (in Russ.).
Nikitina S.A., Khabibrakhmanova V.R., Sysoyeva M.A. Khimiya rastitel'nogo syr'ya, 2014, no. 3, pp. 191–198. DOI: 10.14258/jcprm.1403185. (in Russ.).
Sysoyeva M.A., Khabibrakhmanova V.R., Gamayurova V.S., Tazeyeva A.Kh. Khimiya rastitel'nogo syr'ya, 2008, no. 3, pp. 119–122. (in Russ.).
Khasanov V.V., Slizhov Yu.G., Chumakov A.A., Bazhina S.V. Khimiya rastitel'nogo syr'ya, 2015, no. 2, pp. 43–48. DOI: 10.14258/jcprm.201502533. (in Russ.).
Nakata T., Taji S., Yamada T. Bioorganic & Medicinal Chemistry, 2007, vol. 15, no. 1, pp. 257–264. DOI: 10.1016/j.bmc.2006.09.064.
Chung M.J. Nutrition research and practice, 2010, vol. 4, no. 3, pp. 177–182. DOI: 10.4162/nrp.2010.4.3.177.
Zheng W. Appl. Microbiol. Biotechnol., 2010, vol. 87, pp. 1237–1254. DOI: 10.1007/s00253-010-2682-4.
Chen H., Fu L., Dong P., Zhang X., Lu X. 3rd International Conference on Bioinformatics and Biomedical Engineer-ing, 2009, pp. 1–4. DOI: 10.1109/ICBBE.2009.5162275.
Liu P., Xue J., Tong S., Dong W., Wu P. Molecules, 2018, vol. 23, no. 8, 1948. DOI: 10.3390/molecules23081948.
Eid J.I., Das B. Sci. Rep., 2020, vol. 10, 7406. DOI: 10.1038/s41598-020-64157-3.
Gracheva N.V., Zheltobryukhov V.F., Golovanchikov A.B. Izvestiya VolgGTU, 2014, no. 7(134), pp. 93–97. (in Russ.).
Sushinskaya N.V., Kurchenko V.P. Teoreticheskaya i prikladnaya ekologiya, 2019, vol. 14, pp. 83–87. DOI: 10.25750/1995-4301-2019-4-083-087. (in Russ.).
Senyuk O., Gorovoj L., Zhidkov A., Kovalyov V., Palamar L., Kurchenko V., Kurchenko N., Schroeder H.-Ch. Ad-vances in chitin science, 2005, vol. 8, pp. 430–434.
Hassan M.A., Rouf R., Tiralongo E., May T.W., Tiralongo J. International journal of molecular sciences, 2015, vol. 16, no. 4, pp. 7802–7838. DOI: 10.3390/ijms16047802.
Yakimov P.A. Stupak M.F. Zol'nyye elementy chagi i preparata iz neye. Chaga i yeye lechebnoye primeneniye pri rake IV stadii. [Ash elements of chaga and preparation from it. Chaga and its therapeutic use in stage IV cancer]. Leningrad, 1959, vol. 9, pp. 50–54. (in Russ.).
Lovkova M.L., Sokolova S.M., Buzuk G.N., Bukhovskiy V.Ya., Ponomareva S.M. Prikladnaya biokhimiya i mikrobiologiya, 1999, no. 35–5, pp. 578–589. (in Russ.).
Sysoyeva M.A., Sysoyeva Ye.V., Nosov A.I., Fatykhova A.Z. Vestnik Kazanskogo tekhnologicheskogo universiteta, 2013, no. 7, pp. 192–195. (in Russ.).
Kuznetsova O.Yu. Razrabotka i registratsiya lekarstvennykh sredstv, 2016, vol. 14, no. 1, pp. 128–141. (in Russ.).
Fedoseyeva G.M. Sibirskiy meditsinskiy zhurnal, 2004, no. 8, pp. 66–69. (in Russ.).
Gyul'byakova Kh.N., Marinina T.F., Kazub V.T. Yevraziyskiy Soyuz Uchenykh. Farmatsevticheskiye nauki, 2019, vol. 55, no. 1, pp. 75–76. (in Russ.).
Otmakhov V.I., Petrova Ye.V. Zhurnal Izvestiya TPU, 2004, vol. 307, no. 6, pp. 51–56. (in Russ.).
Gordeyeva I.V. Mezhdunarodnyy nauchno-issledovatel'skiy zhurnal, 2016, no. 10 (52), pp. 9–11. DOI: 10.18454/IRJ.2016.52.153. (in Russ.).
Gosudarstvennaya farmakopeya RF: 13-ye izd. [State Pharmacopoeia of the Russian Federation: 13th ed.]. Moscow, 2015, 1004 p. (in Russ.).
GSO 8487-2003. Standartnyye obraztsy sostava grafitovogo kollektora mikroprimesey. Komplekt SOG-37. [GSO 8487-2003. Standard samples of the composition of the graphite collector of microimpurities. Set SOG-37]. Yekaterinburg, 2003. (in Russ.).
Alekseyenko V.A. Khimicheskiye elementy v geokhimicheskikh sistemakh. Klarki pochv selitebnykh landshaftov: monografiya. [Chemical elements in geochemical systems. Clarks of soils of residential landscapes: monograph]. Ros-tov-on-Don, 2013, 388 p. (in Russ.).
Litvinova T.N., Vyskubova N.K. Nenasheva L.V. Biogennyye elementy. Kompleksnyye soyedineniya. [Biogenic ele-ments. complex compounds]. Rostov-on-Don, 2009, 283 p. (in Russ.).
Fastovets I.A., Verkhovtseva N.V., Pashkevich Ye.B., Netrusov A.I. Problemy agrokhimii i ekologii, 2017, no. 1, pp. 51–62. (in Russ.).
Mirunalini S., Arulmozhi V., Deeplakshmi K., Krishnaveni M. Notulae Scientia Biologica, 2012, vol. 4, no. 4, pp. 55–61. DOI: 10.15835/nsb448051.
Krutenko V.V. Visnyk problem biolohiyi i medytsyny, 2013, no. 3, pp. 19–24. (in Russ.).
Katola V.M. Byullyuten' fiziologii i patologii dykhaniya, 2014, no. 54, pp. 103–110. (in Russ.).
SanPiN 2.3.2.1078-01. Gigiyenicheskiye trebovaniya bezopasnosti i pishchevoy tsennosti pishchevykh produktov. [SanPiN 2.3.2.1078-01. Hygienic requirements for the safety and nutritional value of food products]. Moscow, 2001. (in Russ.).
Gorbunov A.V., Lyapunov S.M., Okina O.I., Frontas'yeva M.V., Pavlov S.S. Otsenka faktorov, vliyayushchikh na mikroelementnyy sostav bazidial'nykh gribov yevropeyskoy chasti Rossii. [Evaluation of the factors influencing the mi-croelement composition of basidiomycetes of the European part of Russia]. Dubna, 2009, 19 p. (in Russ.).
![](http://journal.asu.ru/public/journals/1/article_9738_cover_ru_RU.png)
Copyright (c) 2022 chemistry of plant raw material
![Creative Commons License](http://i.creativecommons.org/l/by/4.0/88x31.png)
This work is licensed under a Creative Commons Attribution 4.0 International License.
This work is licensed under a Creative Commons Attribution 4.0 International License.
The authors, which are published in this journal, agree to the following conditions:
1. Authors retain the copyright to the work and transfer to the journal the right of the first publication along with the work, at the same time licensing it under the terms of the Creative Commons Attribution License, which allows others to distribute this work with the obligatory indication of the authorship of this work and a link to the original publication in this journal .
2. The authors retain the right to enter into separate, additional contractual agreements for the non-exclusive distribution of the version of the work published by this journal (for example, to place it in the university depository or to publish it in a book), with reference to the original publication in this journal.
3. Authors are allowed to post their work on the Internet (for example, in a university repository or on their personal website) before and during the review process of this journal, as this may lead to a productive discussion, as well as more links to this published work.