SYNTHESIS OF METHYL ESTERS OF (Е,2S,3S)-2-ARYLIDENAMINO-3-METHYLVALERIC ACIDS
Abstract
The convenient method of the preparative synthesis of the chiral methyl esters of (Е,2S,3S)-2-arylidenamino-3-methylvaleric acids – derivatives of benzaldehydes of vanniline row was developed. The structure-smell correlation of the compounds obtained was studied. Structure of the compounds synthesized was confirmed by the data of element analysis, IR, UV, NMR 1H and mass spectra.Downloads
Metrics
References
Nelson D.L., Cox M.M. Lehninger Principles of Biochemistry. 5th Ed. New York, 2009. 1100 p.
Huges A.B. Amino Acids, Peptides and Proteins in Organic Chemistry. Vol. 1. Origins and Synthesis of Amino Acids. Weinheim, 2009. 610 p.
Barrett G.C., Elmore D.T. Amino Acids and Peptides. Cambridge, 1998. 480 p.
Oros G., Ujvary I., Nachman R. Antimicrobial properties of o-carboranyl alanine // J. Amino Acids. 1999. Vol. 17, N2. Pp. 357–368.
Попова Л.А., Юрашевич Н.Я., Черевин М.С., Гулевич Т.Г., Решетова М.Д., Книжников В.А. Ферроценилметильные производные аминокислот // Весцi НАН Беларусi. Сер. хiм. наук. 2006. №2. С. 48–51.
Дикусар Е.А., Поткин В.И., Жуковская Н.А. Синтез хиральных азометинов на основе гидрохлорида метилового эфира L-валина и замещенных бензальдегидов ванилинового ряда. // Журнал органической химии. 2010. Т. 46, вып. 5. С. 655–659.
Дикусар Е.А. Синтез хиральных азометинов на основе гидрохлорида метилового эфира L-3-фенилаланина
и замещенных бензальдегидов ванилинового ряда // Журнал органической химии. 2011. Т. 47, вып. 2. С. 213–216.
Дикусар Е.А., Поткин В.И., Рудаков Д.А., Петкевич С.К. Хиральные производные L-валина, L-лейцина, L-изолейцина и L-α-фенилаланина. // Materiały VII Międzynarodowej Naukowi-Praktycznej Konferencji «Perspektywiczne opracowania są nauką i technikani – 2011». 07–15 Listopada 2011 roku. Vol. 49. Przemyśl, , 2011. Pp. 25–27.
Дайер Д.Р. Приложения абсорбционной спектроскопии органических соединений. М., 1970. С. 92.
Дикусар Е.А., Козлов Н.Г., Поткин В.И., Ювченко А.П., Тлегенов Р.Т. Замещенные бензальдегиды ванилинового ряда в органическом синтезе: получение, применение, биологическая активность. Минск, 2011. 446 с.
Grimes R.N. Carboranes. 2th Ed. Amsterdam ; Boston ; Heidelberg ; London ; New York ; Oxford ; Paris ; San Diego ; San Francisco ; Singapore ; Sydney ; Tokyo, 2011. 1139 p.
This work is licensed under a Creative Commons Attribution 4.0 International License.
The authors, which are published in this journal, agree to the following conditions:
1. Authors retain the copyright to the work and transfer to the journal the right of the first publication along with the work, at the same time licensing it under the terms of the Creative Commons Attribution License, which allows others to distribute this work with the obligatory indication of the authorship of this work and a link to the original publication in this journal .
2. The authors retain the right to enter into separate, additional contractual agreements for the non-exclusive distribution of the version of the work published by this journal (for example, to place it in the university depository or to publish it in a book), with reference to the original publication in this journal.
3. Authors are allowed to post their work on the Internet (for example, in a university repository or on their personal website) before and during the review process of this journal, as this may lead to a productive discussion, as well as more links to this published work.