DEVELOPMENT OF METHODS OF QUALITY CONTROL OF GINSENG TINCTURA

  • Владимир Александрович Куркин Samara State Medical University, ul. Chapaevskaia, 89, Samara, 443099 (Russia) Email: Kurkinvladimir@yandex.ru
  • Алина Сергеевна Акушская Samara State Medical University, ul. Chapaevskaia, 89, Samara, 443099 (Russia) Email: akushskaya.as@gmail.com
DOI_disc_logo https://doi.org/10.14258/jcprm.1302177
Keywords: ginseng, Panax ginseng C.A. Meyer, tincture, saponins, thin-layer chromatography, spectrophotometry, standardization

Abstract

There were developed the techniques of qualitative and quantitative analysis of ginseng tinctures (Panax ginseng C.A. Meyer).

Thin-layer chromatography (in the solvent system chloroform – methanol – water, 26 : 14 : 3; detection in the visible range after reaction with phosphowolframic acid) and UV/Visible spectroscopy of native tincture (maximum of absorption at 268±2 nm) and total saponins, purified on polyamide and reacted with 70% sulphuriс acid (maximum of absorption at 280±2 nm, 400±2 nm and 526±2 nm).

The method of quantitative determination of total saponins in tinctura of ginseng by means of direct spectrophotometry (analytical wave-length at 526 nm) was developed. The contents of the total saponins are varied with 0,42% to 0,61% (calculated on ginsenoside Rg1)

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Author Biographies

Владимир Александрович Куркин, Samara State Medical University, ul. Chapaevskaia, 89, Samara, 443099 (Russia)
заведующий кафедрой фармакогнозии с ботаникой и основами фитотерапии, доктор фармацевтических наук, профессор, тел.: (846) 260-33-59
Алина Сергеевна Акушская, Samara State Medical University, ul. Chapaevskaia, 89, Samara, 443099 (Russia)
клинический интерн, тел.: (846) 260-33-59

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Published
2013-06-10
How to Cite
1. Куркин В. А., Акушская А. С. DEVELOPMENT OF METHODS OF QUALITY CONTROL OF GINSENG TINCTURA // chemistry of plant raw material, 2013. № 2. P. 177-182. URL: http://journal.asu.ru/cw/article/view/jcprm.1302177.
Issue
No 2 (2013)
Section
Low-molecular weight compounds

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