COMPONENT COMPOSITION AND BIOLOGICAL ACTIVITY OF ESSENTIAL OILS OF GENUS DRACOCEPHALUM L.

  • Yerlan Melsuly Suleimen LN Gumilev Eurasian National University
  • Anar Bazarovna Myrzagaliyeva S. Amanzholov East Kazakstan State University, 30-th Guards division str., 34, Oskemen, 070019
  • Zharkyn Аbykenovich Ibatayev The Institute of Applied Chemistry, L.N. Gumilyov Eurasian National University, К. Satbayev str., 2, Astana, 010008
  • Zhanar Baktybaevna Iskakova The Institute of Applied Chemistry, L.N. Gumilyov Eurasian National University, К. Satbayev str., 2, Astana, 010008
  • Talant Nurzhakypovich Samarkhanov S. Amanzholov East Kazakstan State University, 30-th Guards division str., 34, Oskemen, 070019
  • Balzhan Zaruetovna Medeubayeva S. Amanzholov East Kazakstan State University, 30-th Guards division str., 34, Oskemen, 070019

Аннотация

This article presents data on the study of the chemical composition, antiradical and cytotoxic activity of three species of the genus Dracocephalum L., which grow in East Kazakstan. Essential oils are obtained from aerial parts of plants D. nutans, D. ruyschiana, D. thymiflorum and the average yield of oil was 0,2%. The chemical composition of essential oils were determined by the GC/MS.

Cytotoxic activity of essential oils was determined by the survival of Artemia salinaaquatic crustaceans. Essential oils of D. nutans, D. ruyschiana and D. thymiflorum in all concentrations (1–10 mg/mL) tested exhibit acute lethal toxicity – all larvae were died. Antiradical activity was determined by the method based on colorimetry of free radicals (DPPH). The experimental results showed that essential oils from D. nutans, D. ruyschiana and D. thymiflorum at all tested concentrations (0,1–1,0 mg/mL) exhibited low antiradical activity compared with the standard drug – butylhydroxyanisole.

 

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Биографии авторов

Yerlan Melsuly Suleimen, LN Gumilev Eurasian National University
the Insitiute of Applied Chemistry
Anar Bazarovna Myrzagaliyeva, S. Amanzholov East Kazakstan State University, 30-th Guards division str., 34, Oskemen, 070019
Doctor of biological sciences, Professor, Vice-rector for academic and educational work
Zharkyn Аbykenovich Ibatayev, The Institute of Applied Chemistry, L.N. Gumilyov Eurasian National University, К. Satbayev str., 2, Astana, 010008
Candidate of Chem. Science, Leading Researcher of theInstitute ofApplied Chemistry 
Zhanar Baktybaevna Iskakova, The Institute of Applied Chemistry, L.N. Gumilyov Eurasian National University, К. Satbayev str., 2, Astana, 010008

Candidate of Chem. Science, Leading Researcher of theInstitute ofApplied Chemistry

 

Talant Nurzhakypovich Samarkhanov, S. Amanzholov East Kazakstan State University, 30-th Guards division str., 34, Oskemen, 070019

Master of geography, Senior Researcher

Balzhan Zaruetovna Medeubayeva, S. Amanzholov East Kazakstan State University, 30-th Guards division str., 34, Oskemen, 070019

Master of chemistry, Senior teacher of department of chemistry 

Литература

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Опубликован
2016-09-02
Как цитировать
[1]
Suleimen, Y.M., Myrzagaliyeva, A.B., IbatayevZ.А., Iskakova, Z.B., Samarkhanov, T.N. и Medeubayeva, B.Z. 2016. COMPONENT COMPOSITION AND BIOLOGICAL ACTIVITY OF ESSENTIAL OILS OF GENUS DRACOCEPHALUM L. Химия растительного сырья. 4 (сен. 2016), 83-88. DOI:https://doi.org/10.14258/jcprm.2016041340.
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Низкомолекулярные соединения