ANALYSIS OF GENUS SPECIFIC PHENOLIC COMPOUNDS IN PLANTS OF THE GENUS RHODIOLA SPP. IN A COMPARATIVE ASPECT
UDC 615.074: 615.322
Abstract
Plants of the genus Rhodiola (Crasulaceae) are actively used in folk medicine around the world. The most studied representative of this genus is Rhodiola rosea L., which is an official species in the Russian Federation. But in the folk medicine of Russia and China, other species of the genus Rhodiola are also used. Thus, in the southern part of Eastern Siberia, Rhodiola quadrifida (Pall.) Fisch et Mey is very popular., in Central Asia - Rhodiola heterodonta (Hook. f. & Thomson) Boriss. To introduce these species of the genus Rhodiola into official medicine, it is necessary to determine marker compounds and select standardization criteria. The purpose of this work was to study phenolic alcohols and their glycosides, established as genus specific, in Rhodiola quadrifida and Rhodiola heterodonta in comparison with Rhodiola rosea by high performance thin layer and liquid chromatography. It has been established that rosarin is characteristic only for R. rosea, while salidroside and tyrosol quantitatively prevail in R. heterodonta and R. quadrifida. Based on the obtained results, it can be assumed that the differences in the chromatographic profile of the studied species can be used to confirm the identity, and the identified compounds can be used to standardize the indicated Rhodiola species.
Downloads
Metrics
References
Chiang H.M., Chen H.C., Wu C.S., Wu P.Y., Wen K.C. Journal of Food and Drug Analysis, 2015, vol. 23, no. 3, pp. 359–369. DOI: 10.1016/j.jfda.2015.04.007.
Panossian A., Wikman G., Sarris J. Phytomedicine, 2010, vol. 17, no. 7, pp. 481–93. DOI: 10.1016/j.phymed.2010.02.002.
Gosudarstvennaya farmakopeya Rossiyskoy Federatsii, XIV izdaniye. [State Pharmacopoeia of the Russian Federation, XIV edition]. Moscow, 2018. URL: http://www.femb.ru/femb/pharmacopea.php. (in Russ.).
Kosakowska O., Bączek K., Przybył J. L., Pióro-Jabrucka E., Czupa W., Synowiec A., Gniewosz M., Costa R., Mondello L., Węglarz Z. Molecules, 2018, vol. 23, no. 7, p. 1767. DOI: 10.3390/molecules23071767.
Liu Z., Liu Y., Liu C. et al. Chemistry Central Journal, 2013, vol. 7, 118. DOI: 10.1186/1752-153X-7-118.
Chiu T.F., Chen L.C., Su D.H. et al. BMC Complementary and Alternative Medicine, 2013, vol. 13, 298. DOI: 10.1186/1472-6882-13-298.
Li T., Zhang H. Chemical and Pharmaceutical Bulletin, 2008, vol. 56, no. 6, pp. 807–814. DOI: 10.1248/cpb.56.807.
Lin K.T., Hsu S.W., Lai F.Y. et al. BMC Complementary and Alternative Medicine, 2016, vol. 16, 127. DOI: 10.1186/s12906-016-1108-y.
Qi Y.-J., Cui S., Lu D.-X. et al. Cancer Cell International, 2015, vol. 15, 81. DOI: 10.1186/s12935-015-0225-x.
Yoshikawa M., Shimada H., Matsuda H., Yamahara J., Murakami N. Chemical and Pharmaceutical Bulletin, 1996, vol. 44, no. 9, pp. 1656–1662. DOI: 10.1248/cpb.44.1656.
Grace M.H., Yousef G.G., Kurmukov A.G., Raskin I., Lila M.A. Natural Product Communications, 2009, vol. 4, no. 8, pp. 1053–1058.
Rakhmatullayeva M.M. Farmatsevticheskiy vestnik Uzbekistana, 2015, no. 3, pp. 42–45.
Lee S.-Y., Shi L.-S., Chu H., Li M.-H., Ho C.-W., Lai F.-Y., Huang C.-Y., Chang T.-C. Evidence-Based Complemen-tary and Alternative Medicine, 2013, 284150. DOI: 10.1155/2013/284150.
Wang Q., Ruan X., Jin Z.H., Yan Q.C., Tu S. Journal of Zhejiang University-SCIENCE B, 2005, vol. 6, pp. 477–482. DOI: 10.1631/jzus.2005.B0477.
Methods for Identification of Herbal Drugs and Herbal Drug Preparations. Rhodiola rosea HPTLC Association. USP41-NF36. 2020. URL: https://www.hptlcassociation.org/methods/methods_for_identification_of_herbals.cfm.
Zhao G., Shi A., Fan Z., Du Y. Oncology Reports, 2015, vol. 33, pp. 2553–2560. DOI: 10.3892/or.2015.3857.
Yang D.W., Kang O.H., Lee Y.S., Han S.H., Lee S.W., Cha S.W., Seo Y.S., Mun S.H., Gong R., Shin D.W., Kwon D.Y. International Journal of Molecular Medicine, 2016, vol. 38, pp. 1864–1870. DOI: 10.3892/ijmm.2016.2781.
You L., Zhang D., Geng H. BMC Complementary Medicine and Therapies, 2021, vol. 21, 146. DOI: 10.1186/s12906-021-03307-0.
An J., Yang H., Zhang Q., Liu C., Zhao J., Zhang L., Chen B. Life Sciences, 2016, vol. 147, pp. 46–58.
Yuan Y., Wang Z., Nan B., Yang C., Wang M., Ye H., Xi C., Zhang Y., Yan H. Toxicology, 2021, vol. 461, 152905. DOI: 10.1016/j.tox.2021.152905.
Gao J., Zhou R., You X. Metabolic Brain Disease, 2016, vol. 31, pp. 771–778. DOI: 10.1007/s11011-016-9813-2.
Seo E.-J., Fischer N., Efferth T. Pharmacological Research, 2018, vol. 129, pp. 262–273. DOI: 10.1016/j.phrs.2017.11.030.
Song D., Zhao M., Feng L., Wang P., Li Y., Li W. Biomedicine & Pharmacotherapy, 2021, vol. 142, 111949. DOI: 10.1016/j.biopha.2021.111949.
Copyright (c) 2022 chemistry of plant raw material
This work is licensed under a Creative Commons Attribution 4.0 International License.
This work is licensed under a Creative Commons Attribution 4.0 International License.
The authors, which are published in this journal, agree to the following conditions:
1. Authors retain the copyright to the work and transfer to the journal the right of the first publication along with the work, at the same time licensing it under the terms of the Creative Commons Attribution License, which allows others to distribute this work with the obligatory indication of the authorship of this work and a link to the original publication in this journal .
2. The authors retain the right to enter into separate, additional contractual agreements for the non-exclusive distribution of the version of the work published by this journal (for example, to place it in the university depository or to publish it in a book), with reference to the original publication in this journal.
3. Authors are allowed to post their work on the Internet (for example, in a university repository or on their personal website) before and during the review process of this journal, as this may lead to a productive discussion, as well as more links to this published work.