CHEMICAL COMPOSITION AND BIOLOGICAL PROPERTIES OF THE KIDNEYS OF POPULUS NIGRA L. OF THE CASPIAN REGION
UDC 582.623.2.581.192.664.64.016.76
Abstract
The chemical composition of low molecular weight organic compounds (NOS) was studied by chromatography-mass spectrometric analysis of Populus nigra L. kidneys. Of the Caspian region and comparative antimicrobial (bactericidal) activity of extractive components with other plants with characteristic antimicrobial properties. The extraction was carried out by percolation in water-alcohol solutions. The study of antimicrobial activity was carried out by the standard CFU method. As a result, 49 compounds were identified, of which 10 remained unidentified. The study of comparative antimicrobial properties of plant extracts showed the complete bactericidal activity of Populus nigra kidneys against opportunistic microorganisms and microflora of air and water, in MIC equal to 0.25 micrograms/ml. Therefore, the NOSES isolated from the kidneys of Populus nigro of the Caspian region have prospects for further study of antioxidant activity for the preparation of biotechnological drugs and pharmaceutical substances.
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Markelov K.A. Caspium Securitatis: zhurnal kaspiyskoy bezopasnosti, 2021, no. 1(1), pp. 11–34. (in Russ.).
Flora Nizhnego Povolzh'ya. Razdel'nolepestnyye dvudol'nyye tsvetkovyye rasteniya (Salicaceae – Droseraceae). Glavnyy botanicheskiy sad im. N.V. Tsitsina RAN. [Flora of the Lower Volga region. Dicotyledonous flowering plants (Salicaceae – Droseraceae). Main Botanical Garden named after. N.V. Tsitsin RAS]. Moscow, 2018, vol. 2-1, 497 p. (in Russ.).
Braslavskiy V.B. Issledovaniye khimicheskogo sostava nekotorykh vidov topolya (Populus L.): dis. … kand. farm. nauk. [Study of the chemical composition of some types of poplar (Populus L.): dis. ...cand. pharm. Sci.]. Samara, 1994, 133 p. (in Russ.).
Braslavskiy V.B., Kurkin V.A., Zhdanov I.P. Rastitel'nyye resursy, 1991, vol. 27, no. 2, pp. 77–81. (in Russ.).
Braslavskiy V.B., Kurkin V.A., Zapesochnaya G.G., Bezrukova N.A. Rastitel'nyye resursy, 1991, vol. 27, no. 3, pp. 130–134. (in Russ.).
Adekenov S.M., Baysarov G.M., Zhabayeva A.N., Suntsova L.P., Dushkin A.V. Khimiya rastitel'nogo syr'ya, 2021, no. 1, pp. 219–226. (in Russ.).
Zapesochnaya G.G., Kurkin V.A., Braslavskiy V.B., Filatova N.V. Khimiya prirodnykh soyedineniy, 2003, no. 4, pp. 263–266. (in Russ.).
Sukhenko L.T. Dikorastushchiye rasteniya flory yuga rossii kak istochnik tsennykh fitokomponentov s protivo-mikrobnymi i bioregulyatornymi svoystvami. [Wild plants of the flora of the south of Russia as a source of valuable phytocomponents with antimicrobial and bioregulatory properties]. Moscow, 2017, 304 p. (in Russ.).
Sentsov M.F., Braslavskiy V.B., Kurkin V.A. Rastitel'nyye resursy, 1997, vol. 33, no. 2, pp. 51–56. (in Russ.).
Astafyeva O.L. Sukhenko L.T., Kurashov E.A., Krylova J.V., Egorov M.A., Bataeva Y.V., Baimukhambetova A.S. Indian journal of pharmaceutical sciences: Indian Pharmaceutical Association, 2018, vol. 80, pр. 434–441. DOI: 10.4172/pharmaceutical-sciences.1000376.
Takha T.V., Nazhmutdinova D.K. Russkiy meditsinskiy zhurnal, 2009, vol. 17 (356), pp. 1072–1074. (in Russ.).
Vichkanova S.A., Tolkachev O.N., Martynova R.G., Arzamastsev Ye.V. Khimiko-farmatsevticheskiy zhurnal, 1982, vol. 16 (12), pp. 107–112. (in Russ.).
Vichkanova S.A., Kolkhir V.K., Krutikova N.M., Adgina V.V., Fateyeva T.V., Sokol'skaya T.A. Trudy VILAR «Khimiya, tekhnologiya, meditsina». [Proceedings of VILAR “Chemistry, technology, medicine”]. Moscow, 2000, pp. 300–309. (in Russ.).
Rastitel'nyye resursy SSSR: Tsvetkovyye rasteniya, ikh khimicheskiy sostav, ispol'zovaniye; semeystva Paeoniaceae - Thymelaeaceae. [Plant resources of the USSR: Flowering plants, their chemical composition, use; family Paeoniaceae - Thymelaeaceae]. Leningrad, 1986, 336 p. (in Russ.).
Ponomarev V.D. Ekstragirovaniye lekarstvennogo syr'ya. [Extraction of medicinal raw materials]. Moscow, 1976, 202 p. (in Russ.).
Patent 1857313 (RU). 2009. (in Russ.).
Kaukhova I.Ye. Rastitel'nyye resursy, 2006, vol. 42, no. 1, pp. 82–91. (in Russ.).
Batayeva Yu.V., Kurashov Ye.A., Krylova Yu.V. Voda: khimiya i ekologiya, 2014, no. 9, pp. 59–68. (in Russ.).
Krylova Yu.V., Kurashov Ye.A., Mitrukova G.G. Khimiya rastitel'nogo syr'ya, 2016, no. 2, pp. 79–88. DOI: 10.14258/jcprm.2016021189. (in Russ.).
Kurashov Ye.A., Krylova Yu.V., Mitrukova G.G. Voda: khimiya i ekologiya, 2012, no. 6, pp. 107–116. (in Russ.).
Isayeva Ye.V., Lozhkina G.A., Ryazanova T.V., Vyalkov A.I., Domrachev D.V., Tkachev A.V. Khimiya rastitel'nogo syr'ya, 2008, no. 1, pp. 63–67. (in Russ.).
Tkachev A.V. Issledovaniye letuchikh veshchestv rasteniy. [Study of plant volatiles]. Novosibirsk, 2008, 969 p. (in Russ.).
Zolotykh D.S., Pozdnyakov D.I., Glushko M.P., Dayronas Zh.V. Khimiya rastitel'nogo syr'ya, 2022, no. 3, pp. 27–47. DOI: 10.14258/jcprm.20220310518. (in Russ.).
Murav'yeva D.A., Samylina I.A., Yakovlev G.P. Farmakognoziya, 4-ye izd. [Pharmacognosy, 4th ed.]. Moscow, 2002, 627 p. (in Russ.).
Kurkin V.A., Braslavskiy V.B., Zapesochnaya G.G. Zhurnal fizicheskoy khimii, 1994, vol. 68, no. 10, pp. 1816–1818. (in Russ.).
Ahmed-Belkacem A., Pozza A., Muñoz-Martínez F., Bates S.E., Castanys S., Gamarro F., Di Pietro A., Pérez-Victoria J.M. Cancer Research, 2005, vol. 65(11), pp. 4852–4860. DOI: 10.1158/0008-5472.can-04-1817.
Lee S., Kim K.S., Park Y., Shin K.H., Kim B.-K. Archives of Pharmacal Research, 2003, vol. 26(1), pp. 43–46. DOI: 10.1007/bf03179930.
Heo M.Y., Sohn S.J., Au W.W. Mutation Research/Reviews in Mutation Research, 2001, vol. 488(2), pp. 135–150. DOI: 10.1016/s1383-5742(01)00054-0.
Rasul A., Millimouno F.M., Ali Eltayb W., Ali M., Li J., Li X. BioMed Research International, 2013, vol. 2013, pp. 1–9. DOI: 10.1155/2013/379850.
Lan X., Wang W., Li Q., Wang J. Molecular Neurobiology, 2015, vol. 53(3), pp. 1794–1801. DOI: 10.1007/s12035-015-9125-2.
Han F., Xiao Y., Lee I.-S. Catalysts, 2021, vol. 11, 1020. DOI: 10.3390/catal11091020.
Braslavskiy V.B., Kurkin V.A., Bakulin B.T. Rastitel'nyye resursy, 1993, vol. 29, no. 4, pp. 77–81. (in Russ.).
Gosudarstvennyy reyestr lekarstvennykh sredstv. [State register of medicines]. Moscow, 2008, vol. 1, 408 p. (in Russ.).
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