COMPONENT COMPOSITIONS OF THE ESSENTIAL OIL AND PHENOLIC COMPOUNDS OF THE AERIAL PART OF LOPHANTHUS SCHTSCHUROVSKIANUS

UDK 615.322:547.913

  • Oydin Karimkhon kizi Askarova Namangan Institute of Engineering and Technology Email: oydinasqarova90@gmail.com
  • Khairulla Mamadievich Bobakulov Acad. S.Yu. Yunusov Institute of the Chemistry of Plant Substances AS RUz; National Research University "Tashkent Institute of Irrigation and Agricultural Mechanization Engineers" Email: khayrulla@rambler.ru
  • Adhamjon Askarali ugli Ganiev Acad. S.Yu. Yunusov Institute of the Chemistry of Plant Substances AS RUz Email: adhamjon1385@gmail.com
  • Nargiza Kudratullaevna Usmanova Namangan State University Email: nargiza_unq@mail.ru
  • Sobirjan Anarmatovich Sasmakov Acad. S.Yu. Yunusov Institute of the Chemistry of Plant Substances AS RUz Email: sasmakov@web.de
  • Farhod Bakir ugli Eshboev Acad. S.Yu. Yunusov Institute of the Chemistry of Plant Substances AS RUz Email: botirov-nepi@mail.ru
  • Эркин Хожиакбарович Ботиров Acad. S.Yu. Yunusov Institute of the Chemistry of Plant Substances AS RUz Email: botirov-nepi@mail.ru
  • Shahnoz Sadykovna Azimova Acad. S.Yu. Yunusov Institute of the Chemistry of Plant Substances AS RUz Email: genlab_icps@yahoo.com
DOI_disc_logo https://doi.org/10.14258/jcprm.20240112489
Keywords: Lophanthus schtschurowskianus Kudr., essential oil, GC-MS analysis, antimicrobial activity, phenolic compounds

Abstract

The component composition of the essential oil (EO) obtained by hydrodistillation from the air dried aerial part of the Lophanthus schtschurowskianus (Regel) Lipsky, growing in the Surkhandarya region of the Republic of Uzbekistan, was studied. By the GC-MS method were identified 57 components in the composition of EO, which was 93.8% of the total amount of oil, of which 52 volatile compounds were identified. The main components of the essential oil were 1,8-cineol (13.4%), viridiflorol (8.5%), α-terpineol (4.3%), terpinen-4-ol (4.2%), τ-cadinol (4.1%), β-spatulenol (3.9%), α-p-dimethylstyrene (2.1%). Oxygenated monoterpenes (33.6%) and oxygenated sesquiterpenes (24.7%) predominate in the composition of the essential oil; compounds related to sesquiterpene hydrocarbons (8.6%) were also found. The composition of the EO components of L. schtschurowskianus significantly differs from the EOs of other studied plant species of the genus Lophanthus.

The antibacterial and antifungal activity of the essential oil, as well as various extracts from the aerial parts of L. schtschurowskianus, was studied using a modified agar diffusion method. Gram-positive bacteria were found to be susceptible to all the studied samples. Among the studied samples, the essential oil showed the highest antibacterial activity against Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli.

Three individual phenolic compounds were isolated from various fractions of a 75% alcoholic extract of the aerial part of L. schtschurowskianus, which, based on the study of 1H, 13C NMR, HSQC and HMBC spectra, were identified as caffeic, rosmarinic acids and luteolin.

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Author Biographies

Oydin Karimkhon kizi Askarova, Namangan Institute of Engineering and Technology

basic doctoral student of the Department of Chemical Technologies

Khairulla Mamadievich Bobakulov, Acad. S.Yu. Yunusov Institute of the Chemistry of Plant Substances AS RUz; National Research University "Tashkent Institute of Irrigation and Agricultural Mechanization Engineers"

Candidate of Chemical Sciences, Head of the Laboratory of Physical Research Methods

Adhamjon Askarali ugli Ganiev, Acad. S.Yu. Yunusov Institute of the Chemistry of Plant Substances AS RUz

basic doctoral student of the laboratory of physical research methods

Nargiza Kudratullaevna Usmanova, Namangan State University

basic doctoral student of the Department of Chemistry

Sobirjan Anarmatovich Sasmakov, Acad. S.Yu. Yunusov Institute of the Chemistry of Plant Substances AS RUz

Doctor of Biological Sciences, senior researcher at the Laboratory of Molecular Genetics

Farhod Bakir ugli Eshboev, Acad. S.Yu. Yunusov Institute of the Chemistry of Plant Substances AS RUz

junior researcher at the Laboratory of Molecular Genetics

Эркин Хожиакбарович Ботиров, Acad. S.Yu. Yunusov Institute of the Chemistry of Plant Substances AS RUz

Doctor of Chemical Sciences, Professor, Head of the Laboratory of Chemistry of Terpenoids and Phenolic Compounds

Shahnoz Sadykovna Azimova, Acad. S.Yu. Yunusov Institute of the Chemistry of Plant Substances AS RUz

Doctor of Biological Sciences, Professor, Head of the Laboratory of Molecular Genetics

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Published
2024-03-07
How to Cite
1. Askarova O. K. kizi, Bobakulov K. M., Ganiev A. A. ugli, Usmanova N. K., Sasmakov S. A., Eshboev F. B. ugli, Ботиров Э. Х., Azimova S. S. COMPONENT COMPOSITIONS OF THE ESSENTIAL OIL AND PHENOLIC COMPOUNDS OF THE AERIAL PART OF LOPHANTHUS SCHTSCHUROVSKIANUS // chemistry of plant raw material, 2024. № 1. P. 234-241. URL: http://journal.asu.ru/cw/article/view/12489.
Issue
No 1 (2024)
Section
Low-molecular weight compounds

Copyright (c) 2024 chemistry of plant raw material

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