ANTIMICROBIAL AND ANTIRADICAL ACTIVITY OF INDIVIDUAL FRACTIONS OF WILD ROSEMARY ESSEN-TIAL OIL IN THE KRASNOYARSK REGION
UDK 615.322+547.913+543.544
Abstract
The biological activity of Ledum palustre L. essential oil is determined by the content of monoterpenes, sesquiterpenes and their oxygen-containing compounds. But the composition of Ledum palustre essential oil differs not only in plants growing in different regions, but also in plants growing in the same region. The purpose of this work is to determine the component composition and study the biological activity of individual fractions of the essential oil of Ledum palustre, growing in the Krasnoyarsk region. The component composition of the fractions obtained by hydrosteam distillation was determined by gas chromatography-mass spectrometry. Antimicrobial activity was studied by the disk diffusion method against strains of Staphylococcus aureus (MSSA), Staphylococcus aureus (MRSA), Escherichia coli, Pseudomonas aeruginosa and Candida albicans. Antiradical activity was assessed using 2,2-diphenyl-1-picrylhydrazyl radical (DPPH). The dominant components of wild rosemary essential oil fractions are p-cymene, trans-pinene, terpinen-4-ol, δ-cadinene, germacron and β-eleenone. The first two fractions of essential oil, enriched with monoterpenes, showed the highest antimicrobial activity. A correlation was revealed between the value of the antiradical activity of the fractions and the content of sesquiterpene hydrocarbons in the fraction. The essential oil of Ledum palustre is promising for further studies of its biological activity.
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Belousova N.I., Khan V.A., Tkachov A.V. Khimiya rastitel'nogo syr'ya, 1999, no. 3, pp. 5–38. (in Russ.).
Izotov D.V., Tagil'tsev Yu.G., Kolesnikova R.D., Tsyupko V.A. Lesnoy zhurnal, 2010, no. 2, pp. 24–30. (in Russ.).
Shikov A.N., Pozharitskaya O.N., Makarov V.G., Wagner H., Verpoorte R., Heinrich M. Journal of Ethnopharma-cology, 2014, vol. 154, pp. 481–536. DOI: 10.1016/j.jep.2014.04.007.
Dampc A., Luczkiewicz M. Fitoterapia, 2013, vol. 85, pp. 130–143. DOI: 10.1016/j.fitote.2013.01.013.
Kurchenko G.A. Veterinariya. Referativnyy zhurnal, 2009, no. 3, p. 806. (in Russ.).
Mofikoya A.O., Kivimӓenpӓӓ M., Blande J.D., Holopainen J.K. Environmental Pollution, 2018, vol. 240, pp. 775–780. DOI: 10.1016/j.envpol.2018.05.031.
Gaponenko V.P., Levashova O.L. Scientific Journal Scitnce Rise, 2015, no. 11, pp. 14–19. DOI: 10.15587/2313-8416.2015.54483. (in Russ.).
Bukreyeva T.V., Shavarda A.L., Matusevich O.V., Morozov M.A. Rastitel'nyye resursy, 2013, vol. 49, pp. 395–403. (in Russ.).
Ganina M.M., Popova O.I. Voprosy biologicheskoy, meditsinskoy i farmatsevticheskoy khimii, 2014, no. 3, pp. 11–19. (in Russ.).
Turusova Ye.V., Nasakin O.Ye. Khimiko-farmatsevticheskiy zhurnal, 2021, vol. 55, no. 11, pp. 33–39. DOI: 10.30906/0023-1134-2021-55-11-33-39. (in Russ.).
Jesionek A., Kokotkiewicz A., Wlodarska P., Filipowicz N., Bogdan A., Ochocka R., Szreniawa-Sztajnert A., Zabiega-la B., Bucinski A., Luczkiewicz M. Acta Biologica Cracoviensia. Series Botanica, 2016, vol. 58, no. 2, pp. 29–43. DOI: 10.1515/abcsb-2016-0019.
Jesionek A., Poblocka-Olech L., Zabiegala B., Bucinski A., Krauze-Baranowska M., Luczkiewicz M. Journal of Chromatography B, 2018, vol. 1086, pp. 63–72. DOI: 10.1016/j.jchromb.2018.04.006.
Jesionek A., Kokotkiewicz A., Wlodarska P., Zabiegala B., Bucinski A., Luczkiewicz M. Plant Cell Tiss Organ Cult., 2017, vol. 131, pp. 51–64. DOI: 10.1007/s11240-017-1261-0.
Jesionek A., Kokotkiewicz A., Krolicka A., Zabiegala B., Luczkiewicz M. Industrial Crops and Products, 2018, vol. 123, pp. 461–469. DOI: 10.1016/j.indcrop.2018.07.013.
Jesionek A., Kokotkiewicz A., Luczkiewicz M. Medicinal Plants. Domestication, Biotechnology and Regional Im-portance. Springer, 2021, vol. 28, pp. 583–604. DOI: 10.1007/978-3-030-74779-4_18.
Zhang L., Wang Y., Xu M., Hu X. International Journal of Food and Nutritional Science, 2017, vol. 4, no. 1, pp. 8–12. DOI: 10.15436/2377-0619.17.1270.
Korpinen R.I., Välimaa A.-L., Liimatainen J., Kunnas S. Molecules, 2021, vol. 26, article 7121. DOI: 10.3390/molecules26237121.
Judzentiene A., Budiene J., Svediene J., Garjonyte R. Molecules, 2020, vol. 25, article 1676. DOI: 10.3390/molecules25071676.
Judzentiene A. Chemija, 2020, vol. 31, no. 4, pp. 269–277. DOI: 10.6001/chemija.v31i4.4324.
Jesionek A., Kokotkiewicz A., Mikosik-Roczynska A., Ciesielska-Figlon K., Luczkiewicz P., Bucinski A., Daca A., Witkowski J.M., Bryl E., Zabiegala B. Fitoterapia, 2019, vol. 139, article 104402. DOI: 10.1016/j.fitote.2019.104402.
Singh B., Gupta J., Mohan R., Gupta R., Pal K. Research Journal of Pharmacy and Technology, 2021, vol. 14, no. 5, pp. 2907–2912. DOI: 10.52711/0974-360X.2021.00510.
Benelli G., Pavela R., Cianfaglione K., Sender J., Danuta U., Maślanko W., Canale A., Barboni L., Petrelli R., Zep-pa L., Aguzzi C., Maggi F. Food and Chemical Toxicology, 2020, vol. 138, article 111184. DOI: 10.1016/j.fct.2020.111184.
Okhlopkova Zh.M., Chirikova N.K. Fundamental'nyye issledovaniya, 2012, vol. 11, no. 6, pp. 1334–1336. (in Russ.).
Raal A., Orav A., Gretchushnikova Т. Natural Product Research, 2014, vol. 28, no. 14, pp. 1091–1098. DOI: 10.1080/14786419.2014.907287.
Judzentiene A., Budiene J., Misiūnas A., Butkiene R. Chemija, 2012, vol. 23, no. 2, pp. 131–135.
Buzuk A.G., Buzuk G.N. Vestnik farmatsii, 2016, no. 4 (74), pp. 18–25. (in Russ.).
Zhang L., Wang Y., Xu M., Hu X. Journal of Analytical Sciences, Methods and Instrumentation, 2017, vol. 7, pp. 47–55. DOI: 10.4236/jasmi.2017.72005.
Ul'yanovskiy N.V., Kosyakov D.S., Pokryshkin S.A., Bogolitsyn K.G., Ul'yanovskaya O.S. Khimiya rastitel'nogo syr'ya, 2014, no. 4, pp. 153–161. DOI: 10.14258/jcprm.201404201. (in Russ.).
Baldwin T.A., Oberbauer S.F. Arctic Science, 2022, vol. 8, no. 3, pp. 916–934. DOI: 10.1139/as-2020-0055.
Mondal S., Hossain I., Islam M.N. Journal of Pharmacognosy and Phytochemistry, 2017, vol. 6, no. 5, pp. 1016–1019.
Jesionek A., Zabiegala B., Bucinski A., Luczkiewicz M. Acta Poloniae Pharmaceutica – Drug Research, 2019, vol. 76, no. 1, pp. 83–92. DOI: 10.32383/appdr/93932.
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