THE FATTY ACID COMPOSITION OF OIL FROM SILYBUM MARIANUM,CULTIVATED IN SAMARA REGION
Abstract
The fruits of milk thistle [(Silybum marianum (L.) Gaertn.), Composite family] are widely used in medical practice as a hepatoprotective agent because they contain flavolignans. However, besides flavolignans, an important group of bioactive compounds of fruit is a fatty oil. The aim of the research was to study the fatty acid composition of milk thistle fruit oil by means of chromatographic-mass spectrometric methods. The object of the study was the oil obtained in the factory "Samaralektravy" from the fruits of milk thistle, cultivated industrially in the Samara region. It was identified 15 fatty acids. The main identified components were unsaturated linoleic (C18:2; 34.8 ± 3.0%) and oleic acids (C18:1; 25,7 ± 3,5%), and the saturated stearic (C18:0; 11,4 ± 1,0 %), palmitic (C16:0; 9,9 ± 0,2%), arachidic (C20: 0; 6,9 ± 0,6%) and behenic acids (C22:0; 3,8 ± 0,4%). The oil contained 61% unsaturated fatty acids and 39% saturated fatty acids. The gas chromatographic method can be useful for identification of a potential pharmaceutical substance "Milk thistle oil”.Downloads
Metrics
References
Kurkin V.A. Farmakognoziia. [Pharmacognosy]. 3 ed. Samara, 2016, 1279 p. (in Russ.).
Kurkin V.A., Zapesochnaia G.G. Khimiia prirodnykh soedinenii, 1987, no. 1, pp. 11–34. (in Russ.).
Kurkin V.A. Khimiko-farmatsevticheskii zhurnal, 2003, vol. 37, no. 4, pp. 27–41. (in Russ.).
Lutsenko S.V., Fel'dman N.B., Lutsenko E.V., Bykov V.A. Rastitel'nye flavolignany. Biologicheskaia aktivnost' i terapevticheskii potentsial. [Plant flavolignanes. Biological activity and therapeutic potential]. Moscow, 2006, 235 p. (in Russ.).
Samigullina L.I., Lazareva D.N. Eksperimental'naia i klinicheskaia farmakologiia, 2004, vol. 67, no. 4, pp. 77–80. (in Russ.).
Sokol'skaia T.A. Khimiko-farmatsevticheskii zhurnal, 2000, vol. 34, no. 9, pp. 27–30. (in Russ.).
Ismaili S.A., Harhar H., Gharby S. et al. Journal of Materials and Environmental Science, 2016, vol. 7, no. 6, pp. 2208–2213.
EMA/HMPC/294188/2013 Committee on Herbal Medicinal Products (HMPC), Assessment report on Silybum maria-num (L.) Gaertn., fructus, 2015.
GOST 31665-2012. Masla rastitel'nye i zhiry zhivotnye. Poluchenie metilovykh efirov zhirnykh kislot. [The state stand-ard is 31665-2012. Vegetable oils and animal fats. Preparation of methyl esters of fatty acids]. Moscow, 2012. (in Russ.).
Subbotina M.A. Tekhnika i tekhnologiia pishchevykh proizvodstv, 2009, no. 4, pp. 54–57. (in Russ.).
This work is licensed under a Creative Commons Attribution 4.0 International License.
The authors, which are published in this journal, agree to the following conditions:
1. Authors retain the copyright to the work and transfer to the journal the right of the first publication along with the work, at the same time licensing it under the terms of the Creative Commons Attribution License, which allows others to distribute this work with the obligatory indication of the authorship of this work and a link to the original publication in this journal .
2. The authors retain the right to enter into separate, additional contractual agreements for the non-exclusive distribution of the version of the work published by this journal (for example, to place it in the university depository or to publish it in a book), with reference to the original publication in this journal.
3. Authors are allowed to post their work on the Internet (for example, in a university repository or on their personal website) before and during the review process of this journal, as this may lead to a productive discussion, as well as more links to this published work.
