ANTIBACTERIAL ACTIVITY OF HYSSOPUS OFFICINALIS ESSENTIAL OILS
Abstract
The steam distillation method was used to obtain samples of essential oil of plants of three varieties Hyssopus officinalis L., cultivated in the conditions of the Republic of Belarus. More than 20 components were identified and determined in the essential oils of plants of the varieties Lazurit, Rozotsvetkovy, Zaveya by gas-liquid chromatography. It has been established that the studied varieties of Hyssopus officinalis belong to the pinocamphone chemotype. The main components are pinocamphone (67.6–76.0%), β-pinene, eugenol, limonene, camphene, sabinene, linalool, 1,8-cineole, α-terpineol, α-pinene, γ-terpinene and pinocampheol. The distribution of the enantiomers of a-and b-pinenes, camphene, limonene and linalool was established in the studied samples.
Antimicrobial activity of essential oils and optical isomers of pure β-pinene was investigated on Staphylococcus aureus, Salmonella alony, Bacillus subtilis, Clostridium sp., Escherichia coli Hfr H, Pseudomonas aeruosa by disc method.
It is shown that (+)-β-pinene showed higher antibacterial activity to (-)-β-pinene. The increased content of (+)-β-pinene in the varieties of Hyssopus officinalis with pink (Rosacea variety) and white (Zaveya variety) aureoles of flowers caused a higher antibacterial activity of their essential oils against Gram-negative and Gram-positive bacteria.
Downloads
Metrics
References
Gurinovich L.K. Efirnyye masla: khimiya, analiz i primeneniye. [Essential oils: chemistry, analysis and application]. Moscow, 2005, 192 p. (in Russ.).
Voytkevich C.A. Efirnyye masla dlya parfyumerii i aromaterapii. [Essential oils for perfumes and aromatherapy]. Moscow, 1999, 329 p. (in Russ.).
Atazhanova G.A. Terpenoidy efirnykh masel rasteniy. Rasprostraneniye, khimicheskaya modifikatsiya i biolo-gicheskaya aktivnost'. [Terpenoids of plant essential oils. Distribution, chemical modification and biological activity]. Moscow, 2008, 288 p. (in Russ.).
Dutova S.V. Farmakologicheskiye i farmatsevticheskiye aspekty deystviya izvlecheniy iz syr'ya efirnomaslichnykh rasteniy: avtoref. dis. ... dok. farm. nauk. [Pharmacological and pharmaceutical aspects of the extracts from raw materi-als of essential oil plants: author. dis. ... doc. farm. sciences]. Volgograd, 2016, 39 p. (in Russ.).
Zheleznyak T.G., Vorniku Z.N. Novyye i netraditsionnyye rasteniya i perspektivy ikh ispol'zovaniya, 2017, pp. 34–36. (in Russ.).
Kuznetsova M.A. Lekarstvennoye rastitel'noye syr'ye i preparaty: spravochnoye posobiye. [Medicinal plant materials and drugs: a reference guide]. Moscow, 1987, 191 p. (in Russ.).
Malankina Ye.L. Lekarstvennyye i efirnomaslichnyye kul'tury. [Medicinal and essential oil cultures]. Moscow, 2016, 367 p. (in Russ.).
Mashanov V.I. Pryano-aromaticheskiye rasteniya. [Spicy aromatic plants]. Moscow, 1991, 256 p. (in Russ.).
Berezko M.N., Berezko O.M., Vecher N.N. Zemledeliye i zashchita rasteniy, 2016, no. 5, pp. 58–59. (in Russ.).
Gubanov V.G. Agrarnyy vestnik Urala, 2016, no. 12, pp. 24–26. (in Russ.).
Bespal'ko L.V., Kharchenko V.A., Shevchenko Yu.P., Ushakova I.T. Ovoshchi Rossii, 2016, no. 2, pp. 60–63. (in Russ.).
Kalinichenko L.V., Malankina Ye.L., Kozlovskaya L.N. Izvestiya TSKhA, 2013, no. 5, pp. 171–176. (in Russ.).
Malankina Ye.L., Kalinichenko L.V. Doklady TSKhA, 2011, vol. 283, pp. 658–661. (in Russ.).
Nayda N.M. Izvestiya Sankt-Peterburgskogo gosudarstvennogo agrarnogo universiteta, 2012, no. 26, pp. 15–20. (in Russ.).
Gosudarstvennyy reyestr sortov Respubliki Belarus'. [The state register of varieties of the Republic of Belarus]. Minsk, 2018, 240 p. (in Russ.).
Myadelets M.A., Domrachev D.V., Cheremushkina V.A. Khimiya rastitel'nogo syr'ya, 2012, no. 1, pp. 111–117. (in Russ.).
Nikitina A.S. Farmakognosticheskoye izucheniye zmeyegolovnika moldavskogo (Dracocephalum moldavica L.) i is-sopa lekarstvennogo (Hyssopus officinalis L.) s tsel'yu obosnovaniya primeneniya v farmatsii i meditsine: dis. … kand. farm. nauk. [Pharmacognostic study of the Moldavian serpentine (Dracocephalum moldavica L.) and medicinal hyssop (Hyssopus officinalis L.) in order to justify the use in pharmacy and medicine: dis. ... Cand. farm. science]. Pyatigorsk, 2008, 210 p. (in Russ.).
Rabotyagov V.D., Shibko A.N. Sbornik nauchnykh trudov Gosudarstvennogo Nikitskogo botanicheskogo sada, 2014, vol. 139, pp. 94–106. (in Russ.).
Popova O.I., Chumakova V.V., Nikitina A.S., Tanskaya Yu.V., Gubanova Ye.A. Voprosy biologicheskoy, meditsinskoy i farmatsevticheskoy khimii, 2010, no. 9, pp. 11–17. (in Russ.).
Hristova Y., Wanner J., Jirovetz L., Stappen I., Iliev I., Gochev V. Biotechnology and Biotechnological Equipment, 2015, vol. 29, pp. 592–601.
Jahantigh O., Najafi F., Badi H.N., Khavari-Nejad R.A., Sanjarian F. Journal of Essential Oil Research, 2016, vol. 28(5), pp. 458–464.
Ahl H.A.H.S-Al, Abbas Z.K., Sabra A.S., Tkachenko K.G. Int. J. Plant Sci. Ecol., 2015, vol. 1, no. 2, pp. 49–53.
Fathiazad F., Hamedeyazdan S. Journal of Pharmacologie, 2011, vol. 5, pp. 1959–1965.
Jankovsky M., Landa T. Hort. Sci.Prague., 2002, vol. 29, no.3, pp. 119–123.
Mitic V., Dordevic S. Facta Universit., 2000, vol. 2, no. 2, pp. 105–108.
Sachivko T.V., Gordeyeva A.P., Bosak V.N. Vestnik BGSKhA. 2017, no. 2, pp. 163–166. (in Russ.).
Shreter A.P. Pravila sbora i sushki lekarstvennykh rasteniy (sbornik instruktsiy). [Rules for the collection and drying of medicinal plants (collection of instructions)]. Moscow, 1985, 328 p. (in Russ.).
Konig W.A., Hochmuth D.H. Journal of Chromatographic Science, 2004, vol. 42, pp. 423–439.
Shibko A.N., Aksenov Yu.V. Ekosistemy, ikh optimizatsiya i okhrana, 2011, no. 4, pp. 127–123. (in Russ.).
Zavislak G. Modern Phytomorphology, 2013, vol. 4, pp. 93–95.
Velikorodov A.V., Kovalev V.B., Kurbanova F.Kh., Shchepetova V.Ye. Khimiya rastitel'nogo syr'ya, 2015, no. 3, pp. 71–76. (in Russ.).
Shibko A.N., Rabogyatov V.D., Aksenov Yu.V. Byulleten' Nikitskogo Botanicheskogo sada, 2011, no. 103, pp. 82–85. (in Russ.).
Leite A.M., Lima E.O., Souza E.L., Diniz M.F.F.M., Trajano V.N., Medeiros I.A. Braz. J. Pharmaceutical Sci., 2007, vol. 43, pp. 121–126.
This work is licensed under a Creative Commons Attribution 4.0 International License.
The authors, which are published in this journal, agree to the following conditions:
1. Authors retain the copyright to the work and transfer to the journal the right of the first publication along with the work, at the same time licensing it under the terms of the Creative Commons Attribution License, which allows others to distribute this work with the obligatory indication of the authorship of this work and a link to the original publication in this journal .
2. The authors retain the right to enter into separate, additional contractual agreements for the non-exclusive distribution of the version of the work published by this journal (for example, to place it in the university depository or to publish it in a book), with reference to the original publication in this journal.
3. Authors are allowed to post their work on the Internet (for example, in a university repository or on their personal website) before and during the review process of this journal, as this may lead to a productive discussion, as well as more links to this published work.