THE ACTIVITY OF INTERMOLECULAR HYDROGEN COMPLEXES OF QUERCETIN WITH GLUCOSE IN REAC-TIONS WITH COTTON OIL PEROXY RADICALS

UDC 547.565:544.421:544.43

  • Natal'ya Ivanovna Belaya Donetsk National University https://orcid.org/0000-0003-3359-3239 Email: nat.iv.belaya@gmail.com
  • Aleksandr Vladimirovich Belyy Donetsk National University Email: a.v.belyj@gmail.com
  • Galina Anatol'yevna Tikhonova Donetsk National University Email: tixonovagala@ya.ru
  • Yaroslav Sergeyevich Udalov Donetsk National University Email: yarikzbest@mail.ru
DOI_disc_logo https://doi.org/10.14258/jcprm.2020036631
Keywords: quercetin, glucose, radical, antioxidant, synergism

Abstract

The presence of a strong synergistic effect of the binary quercetin–glucose composition in the reaction with peroxyl radicals generated during the auto- and initiated oxidation of cottonseed oil was established. The highest antiradical activity showed the synergistic compositions at a ratio of 60 : 40%. The established synergism refers to the type when products, formed during reaction, interacts with peroxy radicals more effectively than the original individual substances. Such products may be intermolecular hydrogen-bonded complexes of quercetin and glucose, the existence of such complexes confirmed by NMR spectroscopy. DFT method showed that the most stable is the donor H-complex, where quercetin acts as a hydrogen donor. A quantitative measure of the electron-donating properties of H complexes – the ionization potential – was calculated in the gas phase. The ionization potential of the donor complex is lower so its reducing ability in reaction with radicals is higher than that of the monomeric antioxidant.This can explain the presence of the maximum synergistic effect in the quercetin-glucose mixture at the ratio of 60 : 40%, when, probably, the proportion of donor H-complexes in the reaction mixture is maximum. Obtained results make it possible to carry out a targeted search for effective antioxidant synergistic flavonoid–carbohydrate compositions in plant extracts.

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Author Biographies

Natal'ya Ivanovna Belaya, Donetsk National University

кандидат химических наук, доцент, доцент кафедры физической химии

Aleksandr Vladimirovich Belyy, Donetsk National University

кандидат химических наук, доцент, декан химического факультета

Galina Anatol'yevna Tikhonova, Donetsk National University

младший научный сотрудник НИЧ кафедры физической химии

Yaroslav Sergeyevich Udalov, Donetsk National University

бакалавр

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Published
2020-10-22
How to Cite
1. Belaya N. I., Belyy A. V., Tikhonova G. A., Udalov Y. S. THE ACTIVITY OF INTERMOLECULAR HYDROGEN COMPLEXES OF QUERCETIN WITH GLUCOSE IN REAC-TIONS WITH COTTON OIL PEROXY RADICALS // chemistry of plant raw material, 2020. № 3. P. 57-65. URL: http://journal.asu.ru/cw/article/view/6631.
Issue
No 3 (2020)
Section
Low-molecular weight compounds

Copyright (c) 2020 chemistry of plant raw material

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