NEW COMPONENTS OF ALCEA NUDIFLORA EXTRACT AFTER MICROWAVE EXTRACTION
UDC 54.056; 54-79; 543.51
Abstract
Alcea nudiflora (Lindl.) Boiss. (Malvaceae) has a wide area of growth in Central Asia, the Altai territory and Western Siberia and has long been used in folk and traditional medicine. Availability of the resource and long-term application practice makes Alcea nudiflora a promising source of valuable biologically active natural compounds. The chemical composition of A nudiflora has been studied after effective microwave assisted extraction (MAE) performed using solvents with different ability to convert microwave energy into heat: hexane, ethyl acetate, methyl tert-butyl ether (MTBE) and ethyl alcohol (EtOH). The selected MAE conditions enabled us to reduce significantly the extraction time and obtain extracts enriched with new compounds. The chemical composition of aboveground part extracts of Alcea nudiflora (Lindl.) Boiss was studied by applying GC/MS method. 13 acids were discovered for the first time, including 6 aromatic acids and 7 unbranched monobasic acids of unsaturated and saturated series, as well as 11 new neutral compounds, including 7 naphthalene derivatives.
Downloads
Metrics
References
Budantsev A.L. Rastitel'nyye resursy Rossii: Dikorastushchiye tsvetkovyye rasteniya, ikh komponentnyy sostav i biolog-icheskaya aktivnost'. [Plant resources of Russia: Wild flowering plants, their component composition and biological ac-tivity]. Moscow, 2009, vol. 2, 520 p. (in Russ.).
Vvedenskiy A.I. Flora Uzbekistana. [Flora of Uzbekistan]. Tashkent, 1959, vol. 4, 169 p. (in Russ.).
Zykova Ye.Yu., Shaulo D.N., Gatilova Ye.A. Turczaninowia, 2017, vol. 20, no. 4, pp. 44–50. DOI: 10.14258/turczaninowia.20.4.6. (in Russ.).
Al-Snafi A.E. Int. J. Pharmtech Res., 2013, vol. 5, no. 3, pp. 1378–1385.
Sezik E., Yesilada E., Shadidoyatov H., Kulivey Z., Nigmatullaev A.M., Aripov H.N., Takaishi Y., Takeda Y., Hon-da G. J. Ethnopharmacol., 2004, vol. 92, no. 2–3, pp. 197–207. DOI:10.1016/j.jep.2004.02.016.
Zaurov D.E., Belolipov I.V., Kurmukov A.G., Sodombekov I.S., Akimaliev A.A., Eisenman S.W. Medicinal Plants of Central Asia: Uzbekistan and Kyrgyzstan, New York, 2012, pp. 15–275. DOI:10.1007/978-1-4614-3912-7_5.
Azab A. Eur. Chem. Bull., 2016, vol. 5, no. 12, pp. 505–514. DOI: 10.17628/ECB.2016.5.505.
Al-Mamoori F., Al-Janabi R. Int. Res. J. Pharm., 2018, vol. 9, no. 6, pp. 22–28. DOI: 10.7897/2230-8407.09684.
Chaturvedi A.K. Sys. Rev. Pharm., 2018, vol. 9, no. 1, pp. 31–35. DOI:10.5530/srp.2018.1.6.
Vinatoru M., Mason T.J., Calinescu I. Trend Anal. Chem., 2017, vol. 97, pp. 159–178. DOI: 10.1016/j.trac.2017.09.002.
Flora SSSR [Flora of the USSR], ed. B.K. Shishkin. Moscow-Leningrad, 1949, vol. 15, pp. 108–111. (in Russ.).
Kukina T.P., Bayandina I.I., Pokrovskiy L.M. Khimiya rastitel'nogo syr'ya, 2007, no. 3, pp. 39–45. (in Russ.).
Tkachev A.V. Issledovaniye letuchikh veshchestv rasteniy. [Study of plant volatiles]. Novosibirsk, 2008, 969 p. (in Russ.).
Hesse C., Hilp K., Kating H., Schaden G. Arch. Pharm., 1977, vol. 310, no. 10, pp. 792–795. DOI: 10.1002/ardp.19773101006.
Ibrahim S.R.M., Mohamed G.A. Phytochem Rev., 2016, vol. 15, no. 2, pp. 279–295. DOI: 10.1007/s11101-015-9413-5.
Popova V., Ivanova T., Nikolova V., Stoyanova A., Docheva M., Hristeva T., Damyanova S., Nikolov N. N. J. Pharm. Sci. & Res., 2017, vol. 9, no. 11, pp. 2045–2051.
Vasudeva N., Sharma S.K. Pharm. Biol., 2008, vol. 46, no. 3, pp. 145–153. DOI: 10.1080/13880200701575320.
Yoo I.D., Yun B.S., Lee I.K., Ryoo I.J., Choung D.H., Han K.H. Phytochemistry, 1998, vol. 47, no. 5, pp. 799–802.
Wongsa N., Kanokmedhakul S., Kanokmedhakul K., Kongsaeree P., Prabpai S., Pyne S.G. Phytochemistry, 2013, vol. 95, pp. 368–374. DOI: 10.1016/j.phytochem.2013.07.017.
Valiei M., Shafaghat A., Salimi F.J. Med. Plants Res., 2011, vol. 5, no. 32, pp. 6972–6976. DOI: 10.5897/JMPR11.963.
Khidyrova N.K., Rakhmatova M.Zh., Kukina T.P., Shakhidoyatov R.Kh., Shakhidoyatov Kh.M. Chem. Nat. Compd., 2012, vol. 48, no. 2, pp. 180–184. DOI: 10.1007/s10600-012-0199-z.
Ertas A., Boga M., Gazioglu I., Yesil Y., Hasimi N., Ozaslan C., Yilmaz H., Kaplan M. Chiang Mai J. Sci., 2016, vol. 43, no. 1, pp. 89–99.
Dudek M., Matławska I., Szkudlarek M. Acta Pol. Pharm., 2006, vol. 63, no. 3, pp. 207–211.
![](http://journal.asu.ru/public/journals/1/article_8361_cover_ru_RU.jpg)
Copyright (c) 2021 chemistry of plant raw material
![Creative Commons License](http://i.creativecommons.org/l/by/4.0/88x31.png)
This work is licensed under a Creative Commons Attribution 4.0 International License.
This work is licensed under a Creative Commons Attribution 4.0 International License.
The authors, which are published in this journal, agree to the following conditions:
1. Authors retain the copyright to the work and transfer to the journal the right of the first publication along with the work, at the same time licensing it under the terms of the Creative Commons Attribution License, which allows others to distribute this work with the obligatory indication of the authorship of this work and a link to the original publication in this journal .
2. The authors retain the right to enter into separate, additional contractual agreements for the non-exclusive distribution of the version of the work published by this journal (for example, to place it in the university depository or to publish it in a book), with reference to the original publication in this journal.
3. Authors are allowed to post their work on the Internet (for example, in a university repository or on their personal website) before and during the review process of this journal, as this may lead to a productive discussion, as well as more links to this published work.