VARIATION OF CONTENT OF URSOLIC AND OLEANOLIC ACIDS IN LEAVES OF PRUNELLA VULGARIS (LA-MIACEAE) GROWING IN NATURE AND IN THE CLIMATIC CHAMBER
Abstract
Prunella vulgaris L. (Lamiaceae) contains a variety of structurally diverse natural products, primarily ursolic acid and oleanolic acid, which possess a wide array of biological properties. The seasonal dynamics of the content of ursolic and oleanolic acids have been determined in leaves of Prunella vulgaris L. growing in natural conditions in the North-West of Russia and in the climatic chamber. In the present study, P. vulgaris was harvested at four developmental stages: vegetation, butonization, blossom and fructification. In sample number 1 (plants grown in the climatic chamber), in phase vegetation and phase butonization, ursolic and oleanolic acids is not detected. In plants grown in the climatic chamber, ursolic and oleanolic acids increased since at blossoming and was maximal at fruiting. In the natural conditions plants (in sample number 2 and 3) the amount of ursolic and oleanolic acids increased since vegetation to budding, was maximal at blossoming and slightly decrease to fruiting.
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