THE COMPARATIVE STUDY OF CHEMICAL COMPOSITION OF HERBS OF PHARMACOPOEIAL SPECIES OF HY-PERICUM L. WITH THE USING OF HIGH PERFORMANCE LIQUID CHROMATOGRAPHY

  • Любовь Николаевна Зимина Samara State Medical University, st. Chapaevskaia, 89, Samara Email: zymynal@gmail.com
  • Владимир Александрович Куркин Samara State Medical University, st. Chapaevskaia, 89, Samara Email: vakur@samaramail.ru
  • Виталий Михайлович Рыжов Samara State Medical University, st. Chapaevskaia, 89, Samara Email: lavr_rvm@mail.ru
DOI_disc_logo https://doi.org/10.14258/jcprm.1301205
Keywords: Hypericum maculatum Grantz., Hypericum perforatum L., herbs, antidepressive activity, flavonoids, hyperoside, rutin, standardization, HPLC

Abstract

The comparative phytochemical study with the using of high performance liquid chromatography of the herbs of Hypericum perforatum L. and Hypericum maculatum Grantz.  was carried out. There were observed the differences in the studied species.  It was established that predominant flavonoid of Hypericum maculatum Grantz. is hyperoside, which has antidepressive activity. It was shown that content of hyperoside in Hypericum maculatum Grantz.  herbs is almost three times higher than in Hypericum perforatum L. (respectively 6,50% and 2,50%). It was determined, that the presence of bisapigenin is characteristic only for Hypericum perforatum L.

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Author Biographies

Любовь Николаевна Зимина, Samara State Medical University, st. Chapaevskaia, 89, Samara
аспирант кафедры фармакогнозии с ботаникой и основами фитотерапии, тел.: (846) 260-33-59, факс: (846) 333-29-76
Владимир Александрович Куркин, Samara State Medical University, st. Chapaevskaia, 89, Samara
заведующий кафедрой фармакогнозии с ботаникой и основами фитотерапии, доктор фармацевтических наук, профессор, тел.: (846) 260-33-59, факс: (846) 333-29-76
Виталий Михайлович Рыжов, Samara State Medical University, st. Chapaevskaia, 89, Samara
ассистент кафедры фармакогнозии с ботаникой и основами фитотерапии, кандидат фармацевтических наук, тел.: (846) 260-33-59, факс: (846) 333-29-76

References

Государственный реестр лекарственных средств. М., 2008. Т. 1. 1398 с.

Куркин В.А. Фармакогнозия : учебник для студентов фармацевтических вузов (факультетов). 2-е изд., перераб. и доп. Самара, 2007. 1239 с.

Зимина Л.Н. Сравнительное химико-фармацевтическое исследование сырья и препаратов зверобоя продырявленного и зверобоя пятнистого // Сборник научных трудов «II Российский фитотерапевтический съезд». М., 2010. С. 132–135.

Published
2013-03-20
How to Cite
1. Зимина Л. Н., Куркин В. А., Рыжов В. М. THE COMPARATIVE STUDY OF CHEMICAL COMPOSITION OF HERBS OF PHARMACOPOEIAL SPECIES OF HY-PERICUM L. WITH THE USING OF HIGH PERFORMANCE LIQUID CHROMATOGRAPHY // chemistry of plant raw material, 2013. № 1. P. 205-208. URL: http://journal.asu.ru/cw/article/view/jcprm.1301205.
Issue
No 1 (2013)
Section
Low-molecular weight compounds

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