СУБКРИТИЧЕСКАЯ ВОДА КАК ИНСТРУМЕНТ ДЛЯ ПОЛУЧЕНИЯ ФИТОКОМПОЗИЦИЙ МЕТАБОЛИТОВ С ВЫСОКОЙ АНТИОКСИДАНТНОЙ АКТИВНОСТЬЮ ИЗ ЛУЗГИ ГРЕЧИХИ (FAGOPYRUM ESCULENTUM):

Nikolai Ivanovich Borisenko; Salima Salimovna Khizrieva; Sergey Nikolaevich  Borisenko; Elena Vladimirovna Maksimenko; Ksenia Olegovna  Shchedrina

doi:10.14258/jcprm.20250215979

Nikolai Ivanovich Borisenko Research Institute of Physical and Organic Chemistry, Southern Federal University Email: boni1912@gmail.com
Salima Salimovna Khizrieva Research Institute of Physical and Organic Chemistry of the Southern Federal University Email: hizrieva@sfedu.ru
Sergey Nikolaevich Borisenko Research Institute of Physical and Organic Chemistry, Southern Federal University Email: sn.borisenko@gmail.com
Elena Vladimirovna Maksimenko Research Institute of Physical and Organic Chemistry, Southern Federal University Email: maksimenkoev52@mail.ru
Ksenia Olegovna Shchedrina Research Institute of Physical and Organic Chemistry, Southern Federal University Email: kshchedrina@sfedu.ru

https://doi.org/10.14258/jcprm.20250215979

Keywords: subcritical water, antioxidant activity, buckwheat husk (Fagopyrum esculentum, polyphenols, flavonoids, polysaccharides, diphenylpicrylhydrazyl (DPPH)

Abstract

Secondary plant metabolite (SPM) extracts with high antioxidant activity (AOA) are increasingly attracting attention as biologically active additives. Green chemistry methods are increasingly being considered for their production. In the presented work, subcritical water medium (SBW) in the temperature range from 120 to 220 °C was used to obtain phytocompositions with high antioxidant activity from common buckwheat husk (BH) (Fagopyrum esculentum). The use of SBW medium for extraction processes allows not only to increase the extraction of SPM from the plant matrix, but also to achieve a change in the phytochemical profile of the obtained extracts, which will determine the AOA of the resulting compositions. It has been demonstrated that the AOA of phytocompositions obtained from buckwheat husk (Fagopyrum esculentum) depends on the extraction conditions and is determined by the polyphenolic profile of the BHE extracts determined by UV/Vis spectrophotometry. It has been shown that the content of polyphenolic compounds and the AOA of the extracts depend on the extraction conditions (temperature of SBW). It has been demonstrated that the extract obtained from BHE in the SBW medium at 220 °C demonstrates the maximum AOA (EC₅₀ = 18.2 μg/ml) among the obtained extracts. The presented results demonstrate the prospects of using SBW for obtaining extracts from BHE with a high content of polyphenols for the development of pharmaceuticals and food additives with high AOA.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Author Biographies

Nikolai Ivanovich Borisenko, Research Institute of Physical and Organic Chemistry, Southern Federal University

Doctor of Chemical Sciences, Chief Researcher

Salima Salimovna Khizrieva, Research Institute of Physical and Organic Chemistry of the Southern Federal University

Candidate of Chemical Sciences, Junior Researcher

Sergey Nikolaevich Borisenko, Research Institute of Physical and Organic Chemistry, Southern Federal University

Candidate of Chemical Sciences, Researcher

Elena Vladimirovna Maksimenko, Research Institute of Physical and Organic Chemistry, Southern Federal University

Researcher

Ksenia Olegovna Shchedrina, Research Institute of Physical and Organic Chemistry, Southern Federal University

student

References

Buchilina A.S., Gun'kova P.I., Ishevskiy A.L., Barakova N.V., Moskvicheva Ye.V., Fomicheva T.I. Vestnik Mezhdu-narodnoy akademii kholoda, 2021, no. 2, pp. 64–72. https://doi.org/10.17586/1606-4313-2021-20-2-64-72. (in Russ.).

Zhukova N.V., Fetisova A.K. Pishchevaya promyshlennost', 2018, no. 11, pp. 37–41. (in Russ.).

Klintsevich V.N., Flyurik Ye.A. Trudy BGTU. Seriya 2: Khimicheskiye tekhnologii, biotekhnologiya, geoekologiya, 2020, no. 1 (229), pp. 68–81. (in Russ.).

Karimova E.R., Yamansarova E.T., Kukovinets O.S., Abdullin M.I. Vestnik bashkirskogo universiteta, 2011, vol. 16, no. 4, pp. 1167–1169. (in Russ.).

Urazova Ya.V. Tekhnologii i oborudovaniye khimicheskoy, biotekhnologicheskoy i pishchevoy promyshlennosti, 2020, pp. 56–58. (in Russ.).

Shekurov V.N., Tarenko B.I., Shekurov K.V. Vestnik Kazanskogo tekhnologicheskogo universiteta, 2014, vol. 17, no. 7, pp. 205–207. (in Russ.).

Zhang Z., Fan S., Duncan G.J., Morris A., Henderson D., Morrice P., Russell W.R., Duncan S.H., Neacsu M. Inter-national Journal of Molecular Sciences, 2023, vol. 24, no. 22, 16310. https://doi.org/10.3390/ijms242216310.

Song C., Ma C., Xiang D. International Journal of Molecular Sciences, 2019, vol. 20, no. 3, 524. https://doi.org/10.3390/ijms20030524.

Dziedzic K., Górecka D., Kucharska M., Przybylska B. Food Research International, 2012, vol. 47, no. 2, pp. 279–283. https://doi.org/10.1016/j.foodres.2011.07.020.

Huang Y., Li F., Meng J., Chen W. Bio Resources, 2018, vol. 13, no. 3, pp. 5153–5163. https://doi.org/10.15376/biores.13.3.5153-5163.

Kovalev V.N., Konkina I.A. Farmatsevticheskiy zhurnal, 1991, no. 3, pp. 72–74. (in Russ.).

Kadritskaya Ye.A. Razrabotka tekhnologii melanina iz luzgi grechikhi i yego ispol'zovaniye v sostave konditerskoy glazuri: dis. ... kand. tekhn. nauk. [Development of technology of melanin from buckwheat husk and its use in confec-tionery glaze: diss. ... Cand. of Technical Sciences]. Yekaterinburg, 2023, 153 p. (in Russ.).

Myagchilov A.V., Sokolova L.I. Khimiya rastitel'nogo syr'ya, 2011, no. 2, pp. 123–126. (in Russ.).

Bashmakov D.I., Lukatkin A.S. Ekologo-fiziologicheskiye aspekty akkumulyatsii i raspredeleniya tyazhelykh metallov u vysshikh rasteniy. [Ecological and physiological aspects of accumulation and distribution of heavy metals in higher plants]. Saransk, 2009, 236 p. (in Russ.).

Anisimova M.M., Kurkin V.A., Yezhkov V.N. Izvestiya Samarskogo nauchnogo tsentra Rossiyskoy akademii nauk, 2010, vol. 12, no. 1-8, pp. 2011–2014. (in Russ.).

Semwal R.B, Joshi S.K., Semwal R.B., Semwal D.K. Phytochemistry Letters, 2021, vol. 46, pp. 119–128. https://doi.org/10.1016/j.phytol.2021.10.006.

Sun X.Y., Li L.J., Dong Q.X., Zhu J., Huang Y.R., Hou S.J., Yu X.L., Liu R.T. Journal of neuroinflammation, 2021, vol. 18, no. 1, pp. 1–14. https://doi.org/10.1186/s12974-021-02182-3.

Tigrine C., Bouriche H., Kameli A. Der Pharma Chemica, 2016, vol. 8, no. 20, pp. 344–349.

Sychev I.A., Kalinkina O.V., Laksayeva Ye.A. Rossiyskiy mediko-biologicheskiy vestnik imeni akademika I.P. Pavlova, 2009, no. 4, pp. 143–148. (in Russ.).

Gulpinar A.R., Orhan I.E., Kan A., Senol F.S., Celik S.A., Kartal M. Food research international, 2012, vol. 46, no. 2, pp. 536–543. https://doi.org/10.1016/j.foodres.2011.08.011.

Włoch A., Strugała P., Pruchnik H., Żyłka R., Oszmiański J., Kleszczyńska H. The Journal of Membrane Biology, 2016, vol. 249, no. 1-2, pp. 155–170. https://doi.org/10.1007/s00232-015-9857-y.

Pedreiro S., Figueirinha A., Silva A.S., Ramos F. Coatings, 2021, vol. 11, no. 11, 1393. https://doi.org/10.3390/coatings11111393.

Galkin A.A., Lunin V.V. Uspekhi khimii, 2005, vol. 74, no. 1, pp. 24–40. https://doi.org/10.1070/RC2005v074n01ABEH001167. (in Russ.).

Lekar' A.V., Filonova O.V., Borisenko S.N., Maksimenko E.V., Vetrova Ye.V., Borisenko N.I., Minkin V.I. Sverkhkriticheskiye flyuidy: teoriya i praktika, 2012, vol. 7, no. 4, pp. 4–15. (in Russ.).

Khizrieva S.S., Borisenko S.N., Maksimenko E.V., Zharkova G.V., Borisenko N.I. Khimiya rastitel'nogo syr'ya, 2023, no. 2, pp. 241–251. https://doi.org/10.14258/jcprm.20230211437. (in Russ.).

Vetrova E.V., Maksimenko E.V., Borisenko S.N., Lekar A.V., Borisenko N.I., Minkin V.I. Russian Journal of Physi-cal Chemistry B, 2017, vol. 11, pp. 1202–1206. https://doi.org/10.1134/S1990793117070193.

Maksimenko E.V., Lekar A.V., Borisenko S.N., Khizrieva S.S., Vetrova E.V., Borisenko N.I., Minkin V.I. Russian Journal of Physical Chemistry B, 2018, vol. 12, pp. 1269–1275. https://doi.org/10.1134/S1990793118080092.

Vetrova E.V., Maksimenko E.V., Khizrieva S.S., Bugaeva A.F., Borisenko N.I., Minkin V.I. Journal of natural sci-ence, biology, and medicine, 2017, vol. 8, no. 2, pp. 213–215. https://doi.org/10.4103/0976-9668.210009.

Zemnukhova L.A., Kolzunova L.G., Shkorina E.D. Russian Journal of Applied Chemistry, 2007, vol. 80, no. 6, pp. 1007–1011. https://doi.org/10.1134/S1070427207060316.

Zemnukhova L.A., Shkorina Ye.D., Filippova I.A. Khimiya rastitel'nogo syr'ya, 2005, no. 2, pp. 51–54. (in Russ.).

Zemnukhova L.A., Shkorina Ye.D., Fedorishcheva G.A. Zhurnal prikladnoy khimii, 2005, vol. 78, no. 2, pp. 329–333. (in Russ.).

Zemnukhova L.A., Chernov B.B., Shkorina Ye.D., Shchetinina G.P. Transportnoye delo Rossii, 2006. special issue 7, pp. 149–152. (in Russ.).

Shukla A.K., Iravani S. Green synthesis, characterization and applications of nanoparticles. Elsevier, 2018. https://doi.org/10.1016/B978-0-08-102579-6.00001-0.

Ying S., Guan Z., Ofoegbu P.C., Clubb P., Rico C., He F., Hong J. Environmental Technology & Innovation, 2022, vol. 26, 102336. https://doi.org/10.1016/j.eti.2022.102336.

Józwiak T., Filipkowska U., Kowalkowska A., Struk-Sokoowska J., Werbowy D. Journal of Environmental Chemical Engineering, 2021, vol. 9, no. 2, 105092. https://doi.org/10.1016/j.jece.2021.105092.

Beni A.A., Esmaeili A. Environmental Technology & Innovation, 2020, vol. 17, 100503. https://doi.org/10.1016/j.eti.2019.100503.

Tongdeesoontorn W., Mauer L.J., Wongruong S., Sriburi P., Reungsang A., Rachtanapun P. Polymers, 2021, vol. 13, no. 7, 1117. https://doi.org/10.3390/polym13071117.

Khizrieva S.S., Borisenko S.N., Maksimenko E.V., Zharkova G.V., Borisenko N.I. Khimiya rastitel'nogo syr'ya, 2022, no. 2, pp. 137–146. https://doi.org/10.14258/jcprm.20220210519. (in Russ.).

Tutel'yan V.A., Eller K.I., Aleshko-Ozhevskiy Yu.P. Rukovodstvo po metodam kontrolya kachestva i bezopasnosti biologicheski aktivnykh dobavok k pishche. [Guide to methods of quality control and safety of biologically active food supplements]. Moscow, 2004, vol. 240, pp. 124–126. (in Russ.).

Khizrieva S.S., Borisenko S.N., Maksimenko E.V., Ippolitova A.V., Shchedrina K.O., Borisenko N.I., Minkin V.I. Sverkhkriticheskiye flyuidy: teoriya i praktika, 2024, vol. 19, no. 3, pp. 79–92. https://doi.org/10.34984/SCFTP.2024.19.3.006. (in Russ.).

SUBCRITICAL WATER AS A TOOL FOR OBTAINING PHYTOCOMPOSITIONS OF METABOLITES WITH HIGH ANTIOXIDANT ACTIVITY FROM BUCKWHEAT HUSKS (FAGOPYRUM ESCULENTUM)

UDC 542.06.542.93.547.918.615.322.634.572

Abstract

Downloads

Metrics

Author Biographies

References