ANALYSIS OF THE CHEMICAL COMPOUNDS OF THE PLANT LAGOTIS KOROLKOWII (PLANTAGINACEAE)
UDC 543.544.5.068.7+581.192.2:577.112.3
Abstract
This study is the first to analyze the flavonoids, amino acids, and vitamins present in the Lagotis korolkowii plant distributed in the territory of Uzbekistan. Twenty amino acids were identified in the samples, of which eight were non-essential, eight were essential, and four were conditionally essential. The total amino acid content of the roots was 9.35 mg/g, whereas that of the aerial parts was 68.35 mg/g. According to the comparative analysis, the aerial parts of Lagotis korolkowii were quantitatively richer in amino acids than the roots. Flavonoids in various parts of Lagotis korolkowii were analyzed for the first time. The results showed that the aerial parts of the plant contained kaempferol, rutin, hypolaetin, hyperoside, and apigenin. Additionally, it was found for the first time that Lagotis korolkowii contains large amounts of vitamins B and C and PP. The obtained data allowed us to consider Lagotis korolkowii as a source of flavonoids, valuable amino acids with a wide spectrum of pharmacological activity, and rich in vitamins, which can be used for the development of new food supplements and pharmaceutical substances.
Downloads
Metrics
References
Plants of the World Online. Facilitated by the Royal Botanic Gardens, Kew. URL: https://powo.science.kew.org/.
Sennikov A.N. Flora Uzbekistana [Flora of Uzbekistan]. Tashkent, 2017, vol. 2, 200 p. (in Russ.).
Opredelitel' rasteniy Sredney Azii. Kriticheskiy konspekt flory. [Plant Identification guide of Central Asia. Critical out-line of flora]. Tashkent, 1993, vol. 10, 692 p. (in Russ.)
Li-juan Y., Xiao-dong Y., Shu Y., Jing-feng Z., Hong-bin Z., Liang L. Chemistry of Natural Compounds, 2006, vol. 42(6), pp. 649–651.
Maksudov M.S, Umarova R.U, Tashhadjayev B., Saatov Z., Abdullayeva N. Chemistry of Natural Compounds, 1995, vol. 31(1), pp. 48–54.
Zhu Ji-X., Hai-Yan Y., Wei-Qiong H., Cheng J., Liu Y., Li-Tao Yi, Hong-Yu Ch. Infammopharmacology, 2021, vol. 29, pp. 1187–1200. https://doi.org/10.1007/s10787-021-00844-5.
Zhang D., Tan L., Yao L., Tao W., Gong R., Luo Rong Q., Cao W. Evidence-Based Complementary and Alternative Medicine, 2020, pp. 1–14. https://doi.org/10.1155/2020/9726431.
Lagotis korolkowii (Regel & Schmalh.) Maxim. URL: https://www.plantarium.ru/page/view/item/21921.html (in Russ.).
Panche A.N., Diwan A.D., Chandra S.R. Journal of nutritional science, 2016, vol. 5, e47. https://doi.org/10.1017/jns.2016.41.
Genchi G. Amino acids, 2017, vol. 49. pp. 1521–1533.
Sohibov D. Vitaminlar va ularning inson hayotidagi ahamiyati. [Vitamins and their importance in human life]. Tash-kent, 1991, 99 p. (in Uzb.).
Coven S.A., Strydom D.J. Journal of Analytical Biochemistry, 1988, vol. 17, no. 1, pp. 1–16. https://doi.org/10.1016/0003-2697(88)90512-x.
Imomova M.Y., Abduganiev Y.B. Universum: khimiya i biologiya, 2019, vol. 9(63), pp. 13–18. (in Russ.)
Askarov I.R., Abdullayev Sh.Sh., Mamatkulova S.A. Journal of Chemistry Goodsand Traditional Medicine, 2023, vol 2(2), pp. 84–101.
Imomova M., Karimova S. Journal of Chemistry of Goods and Traditional Medicine, 2022, vol. 1, pp. 70–81.
Mirzaeva Z.O., Askarov I.R., Topvoldiev T. Journal of Chemistry Goodsand Traditional Medicine, 2023, vol. 2, pp. 74–83.
Sarian M.N., Ahmed Q.U., Mat So’ad S.Z., Alhassan A.M., Murugesu S., Perumal V., Latip J. BioMed Research In-ternational, 2017, vol. 1, 8386065. https://doi.org/10.1155/2017/8386065.
Mabry T.S., Markham R.K., Thomson M.B. The systematic identification of flavonoids. Springer-Verlaq, Berlin-Heidelberg-New York, 1970, 151 p.
Badhani B., Sharma N., Kakkar R. Rsc Advances, 2015, vol. 5 (35), pp. 27540–27557.
Wu G. Amino acids, 2009, vol. 37, pp. 1–17. https://doi.org/10.1007/s00726-009-0269-0.
Copyright (c) 2025 chemistry of plant raw material

This work is licensed under a Creative Commons Attribution 4.0 International License.

This work is licensed under a Creative Commons Attribution 4.0 International License.
The authors, which are published in this journal, agree to the following conditions:
1. Authors retain the copyright to the work and transfer to the journal the right of the first publication along with the work, at the same time licensing it under the terms of the Creative Commons Attribution License, which allows others to distribute this work with the obligatory indication of the authorship of this work and a link to the original publication in this journal .
2. The authors retain the right to enter into separate, additional contractual agreements for the non-exclusive distribution of the version of the work published by this journal (for example, to place it in the university depository or to publish it in a book), with reference to the original publication in this journal.
3. Authors are allowed to post their work on the Internet (for example, in a university repository or on their personal website) before and during the review process of this journal, as this may lead to a productive discussion, as well as more links to this published work.







