PHYTOCHEMICAL STUDY OF AERIAL PARTS OF TARAXACUM OFFICINALE WIGG.

  • Владимир (Vladimir) Александрович (Aleksandrovich) Куркин (Kurkin) Samara State Medical University Email: Kurkinvladimir@yandex.ru
  • Анастасия (Anastasija) Викторовна (Viktorovna) Азнагулова (Aznagulova) Samara State Medical University Email: nastja.beg@mail.ru
DOI_disc_logo https://doi.org/10.14258/jcprm.2017011027
Keywords: Taraxacum officinale Wigg., dandelion, aerial parts, phenylpropanoids, caftaric acid, caffeic acid, chlorogenic acid, flavonoids, tricin, luteolin, cynaroside, triterpene saponins, taraxasterol, TLC, spectrophotometry

Abstract

As the results of the chemical study of the aerial parts of the dandelion (Taraxacum officinale Wigg.) there were isolated for the first time the caftaric acid (21-caffeoyltartaric acid), tricin (5,7,41-trihydroxy-31,51-dimethoxyflavone), caffeic acid, chlorogenic acid, luteolin (5,7,31,41-tetrahydroxyflavone), cynaroside (7-О-b-D-glucopyranoside of 5,7,31,41-tetrahydroxyflavone) and taraxasterol (triterpene saponin), chemical structures of which there were elucidated for the first time by means of 1H-NMR-, 13C-NMR-, UV-spectroscopy, mass spectrometry and several chemical transformations (acid an enzymatic hydrolysis).

There were substantiated the expediency of the using for the determination of identity of the new type of medicinal vegetable raw materials of Taraxacum officinale herbs of TLC by means of the detection of the dominating phenylpropanoid, caftaric acid in the presence of state standard sample of cynaroside, having comparable values of the size of Rf with the analyzed compound.

For pharmacopoeial chromotographic analysis of of Taraxacum officinale herbs there was recommended the using of the chromotographic plates «Sorbfil PTSKH-AF-A-UV» in the solvent system: chloroform n-butanol-ice acetic acid-water in the ratio of 4 : 1 : 2 (detection of compounds on chromatograms in UV light at wavelength 254 nm and by means of the spraying with thealkaline solution of the diazobenzolsulfoacid.

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Author Biographies

Владимир (Vladimir) Александрович (Aleksandrovich) Куркин (Kurkin), Samara State Medical University
доктор фармацевтических наук, профессор, заведующий кафедрой фармакогнозии с ботаникой и основами фитотерапии
Анастасия (Anastasija) Викторовна (Viktorovna) Азнагулова (Aznagulova), Samara State Medical University
аспирант

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Published
2017-01-21
How to Cite
1. Куркин (Kurkin)В. (Vladimir) А. (Aleksandrovich), Азнагулова (Aznagulova)А. (Anastasija) В. (Viktorovna) PHYTOCHEMICAL STUDY OF AERIAL PARTS OF TARAXACUM OFFICINALE WIGG. // chemistry of plant raw material, 2017. № 1. P. 99-105. URL: http://journal.asu.ru/cw/article/view/1027.
Issue
No 1 (2017)
Section
Low-molecular weight compounds

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