ANALYSIS OF ACETONE, CHLOROFORM AND DIETHYL ETHER EXTRACTS OF ARTEMISIA ABSINTHIUM L., ARTEMISIA ARMENIACA LAM. AND ARTEMISIA LATIFOLIA LEDEB.

UDC 577.13 577.19

  • Stanislav Gennad'yevich Rzhevsky All-Russian Research Institute of Forest Genetics, Breeding and Biotechnology Email: slavaosin@yandex.ru
  • Mikhail Andreyevich Potapov Voronezh State University Email: amidines@mail.ru
  • Khidmet Safarovich Shikhaliev Voronezh State University
DOI_disc_logo https://doi.org/10.14258/jcprm.20230111293
Keywords: Wormwood, Armenian wormwood, Broad-leaf wormwood, essential oil herbs, gas chromatograph-mass spectroscopy

Abstract

This paper presents the results of the analysis of acetone, chloroform and diethyl ether extracts of three types of wormwood: Artemisia absinthium L., Artemisia armeniaca Lam. and Artemisia latifolia Ledeb., performed by gas chromatography–mass spectroscopy. β-myrcene was found in chloroform extracts of A. absinthium and A. latifolia from biologically active substances; in extracts of A. armeniaca and A. latifolia, pinene; 3,6-difluoro-4-[1-hydroxy-2-(methiamino)ethyl]benzene-1,2-diol, ethyl palmitate, β-phellandrene are specific for A. absinthium; for A. armeniaca, herniarin and d-limonene; for A. latifolia, γ-sitosterol and farnesol. In acetone extracts of all three types, such biologically active substances as γ-sitosterol, phytol were found; extracts of A. absinthium and A. armeniaca revealed α-cubeben; in extracts of A. armeniaca and A. latifolia – vitamin E; in extracts of A. absinthium and A. latifolia – azafrin. Specific for these extracts of A. absinthium were β-phellandrene, estafiantin, β-elemen, yangambin, β-santalol, caryophyllene, lycopene; for A. armeniaca, α-phellandrene and γ-element; for A. latifolia – hematoporphyrin and laminitol. In the diethyl ether extract of A. absinthium, such biologically active substances as arborescin and yangambin were found; in the extract of A. armeniaca – D-limonene; A. latifolia extract contains hematoporphyrin. Based on the data obtained, it should be assumed that preparations of these plant species may have antibacterial, antioxidant, and anti-inflammatory activity.

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Author Biographies

Stanislav Gennad'yevich Rzhevsky, All-Russian Research Institute of Forest Genetics, Breeding and Biotechnology

младший научный сотрудник

Mikhail Andreyevich Potapov, Voronezh State University

ведущий инженер кафедры органической химии

Khidmet Safarovich Shikhaliev, Voronezh State University

доктор химических наук, профессор

References

Takhtadzhan A.L. Konspekt flory Kavkaza. [Abstract of the flora of the Caucasus]. St. Petersburg, Moscow, 2008, vol. 3-1, 469 p. (in Russ.).

Gosudarstvennaya farmakopeya Rossiyskoy Federatsii, 13 izdaniye. [State Pharmacopoeia of the Russian Federation, 13th edition]. Moscow, 2015, vol. 2, 1004 p. (in Russ.).

Mojarrab M., Lagzianb M., Emamic S.A., Asilic J., Tayarani-Najaranb Z. Revista Brasileira de Farmacognosia, 2013, vol. 23, no. 5, pp. 783−788.

Mojarrab M., Shiravand A., Delazar A. The Scientific World Journal, 2014, vol. 6. DOI: 10.1155/2014/825370.

Otto M. Sovremennyye metody analiticheskoy khimii. [Modern methods of analytical chemistry]. Moscow, 2003, vol. 2, 64 p. (in Russ.).

Mitić-Culafić D., Zegura B., Nikolić B., Vuković-Gacić B., Knezević-Vukcević J., Filipic M. Food and Chemical Toxi-cology, 2009, vol. 47, no. 1, pp. 260–266. DOI: 10.1016/j.fct.2008.11.015.

da Silva A.C., Lopes P.M., de Azevedo M.M., Costa D.C., Alviano C.S., Alviano D.S. Molecules, 2012, vol. 17, no. 6, pp. 6305–6316. DOI: 10.3390/molecules17066305.

Chen G.T., King M., Gusovsky F., Creveling C.R., Daly J.W., Chen B.H., Nie J.Y., Kirk K.L. Journal of Medicinal Chemistry, 1993, vol. 36, no. 24, pp. 3947–3955.

Saeed N.M., El-Demerdash E., Abdel-Rahman H.M., Algandaby M.M., Al-Abbasi F.A., Abdel-Naim A.B. Toxicology and Applied Pharmacology, 2012, vol. 264, no. 1, pp. 84–93. DOI: 10.1016/j.taap.2012.07.020.

Cheng Z., Jiang J., Yang X., Chu H., Jin M., Li Y. et al. Environmental toxicology and pharmacology, 2018, vol. 54, pp. 28−33. DOI: 10.1016/j.etap.2018.05.005.

Belikov V.G. Uchebnoye posobiye po farmatsevticheskoy khimii. [Pharmaceutical Chemistry Study Guide]. Moscow, 1979, 552 p. (in Russ.).

Aydin T., Erol H.S., Cakir A., Yildirim S., Salam Y.S., Halici M. Journal Pharmaceutical Care & Health Systems, 2017, no. 4, p. 22. DOI: 10.4172/2376-0419-C1-023.

Farré-Armengol G., Filella I., Llusià J., Peñuelas J. Molecules, 2017, vol. 22, no. 7. DOI: 10.3390/molecules22071148.

Moon Y.S., Lee H.S., Lee S.E. Applied Biological Chemistry, 2018, vol. 61, no. 2, pp. 243–250. DOI: 10.1007/s13765-018-0352-x.

Savasteyeva A.V., Perunova N.B., Ivanova Ye.V., Chelpachenko O.V. Uspekhi meditsinskoy mikologii, 2014, vol. 12, pp. 61–63. (in Russ.).

Rioja A., Pizzey A.R., Marson C.M., Thomas N.S. FEBS Letters, 2000, vol. 467, no. 2–3, pp. 291–295.

Sain S., Naoghare P.K., Devi S.S., Daiwile A., Krishnamurthi K., Arrigo P., Chakrabarti T. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 2014, vol. 13, no. 1, pp. 45–55.

Gerson F.B.S., Dunckld G.G. Nature, 1963, vol. 200, p. 679.

Sankar M., Ramachandran B., Pandi B., MutharasaPpan N., Ramasamy V., Prabu P.G. et al. Frontiers in molecular bi-osciences, 2021, vol. 8, article 637122. DOI: 10.3389/fmolb.2021.637122.

Gao K., Song Y.P., Song A. BioData mining, 2020, vol. 13, no. 1, pp. 1–20.

McGinty D., Letizia C.S., Api A.M. Food and Chemical Toxicology, 2010, no. 48, pp. 59–63.

Aydarkhanov B.B., Lokshina E.A., Lenskaya Ye.G. Voprosy meditsinskoy khimii, 1989, vol. 35, no. 3, pp. 2–9. (in Russ.).

Yang S., Chou G., Li Q. Phytomedicine, 2018, vol. 47, pp. 12–22. DOI: 10.1016/j.phymed.2018.04.042.

Park S.Y., Jung W.J., Kang J.S., Kim C.M., Park G., Choi Y.W. International journal of molecular medicine, 2015, vol. 35, no. 2, pp. 525–532. DOI: 10.3892/ijmm.2014.2031.

Palacios-Espinosa J.F., Núñez-Aragón P.N., Gomez-Chang E., Linares E., Bye R., Romero I. Molecules, 2021, vol. 26, no. 12, p. 3654. DOI: 10.3390/molecules26123654.

Castro-Faria-Neto H.C., Araújo C.V., Moreira S., Bozza P.T., Thomas G., Barbosa-Filho J.M. et al. Planta medica, 1995, vol. 61, no. 2, pp. 106–112.

Paulpandi M., Kannan S., Thangam R., Kaveri K., Gunasekaran P., Rejeeth C. Phytomedicine, 2012, vol. 19, no. 3-4, pp. 231–235. DOI: 10.1016/j.phymed.2011.11.006.

Krylov I.A., Uteshev D.B. Eksperimental'naya i klinicheskaya farmakologiya, 2002, vol. 65, no. 2, pp. 76–78. (in Russ.).

Siqueira H.D.S., Neto B.S., Sousa D.P., Gomes B.S., da Silva F.V., Cunha F.V.M., Wanderley C.W.S., Pinheiro G., Cândido A.G.F., Wong D.V.T., Ribeiro R.A., Lima-Júnior R.C.P., Oliveira F.A. Life Science, 2016, vol. 160, pp. 27–33. DOI: 10.1016/j.lfs.2016.07.008.

Nunes T.A., Costa L.H., De Sousa J.M.S., De Souza V.M.R., Rodrigues R.R.L., Val M.D.C.A., Pereira A.C.T.D.C., Ferreira G.P., Da Silva M.V., Da Costa J.M.A.R., Véras L.M.C., Diniz R.C., Rodrigues K.A.D.F. Chem Biol Interact., 2021, vol. 339, article 109429. DOI: 10.1016/j.cbi.2021.109429.

Klimentov M.N., Zaynetdinov M.R., Yakovlev A.A. Sovremennyye tendentsii razvitiya nauki i tekhnologiy, 2016, no. 4-2, p. 35. (in Russ.).

Tserkovskiy D.A., Aleksandrova Ye.N., Laptsevich T.P., Istomin Yu.P. Biomedical Photonics, 2014, vol. 3, no. 2, pp. 18–23. (in Russ.).

Howard A.J., Ozer C., Oak Z. Carless H.A.J., Oak O.Z. Tetrahedron Letters, 1991, vol. 32, no. 13, pp. 1671–1674.

Martins A., Mignon R., Bastos M., Batista D., Neng N.R., Nogueira J.M., Vizetto-Duarte C., Custódio L., Varela J., Rauter A.P. Phytother Res., 2014, vol. 28, no. 9, pp. 1329–1334. DOI: 10.1002/ptr.5133.

Published
2023-03-13
How to Cite
1. Rzhevsky S. G., Potapov M. A., Shikhaliev K. S. ANALYSIS OF ACETONE, CHLOROFORM AND DIETHYL ETHER EXTRACTS OF ARTEMISIA ABSINTHIUM L., ARTEMISIA ARMENIACA LAM. AND ARTEMISIA LATIFOLIA LEDEB. // chemistry of plant raw material, 2023. № 1. P. 181-192. URL: http://journal.asu.ru/cw/article/view/11293.
Issue
No 1 (2023)
Section
Low-molecular weight compounds

Copyright (c) 2023 chemistry of plant raw material

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