ECOLOGICAL AND HYGIENIC ASSESSMENT OF THE QUALITY OF BURDOCK ROOTS OF LARGE FLORA OF URBANIZED TERRITORIES OF THE CENTRAL BLACK EARTH REGION
UDK 615.322:574.24
Abstract
The roots of the bladder are mainly used in the form of aqueous extracts, and the pharmacological effect is due to water-soluble compounds based on polysaccharides. The study of the peculiarities of accumulation of this group of compounds is relevant. The aim of this study the relationship between the accumulation of heavy metals and arsenic and biologically active substances in the roots of ordinary burdock, collected on the territory of the Voronezh region in biogeocenoses experiencing various anthropogenic effects. In the Voronezh region, 51 points of harvesting plant raw materials were selected. The study of the content of heavy metals and arsenic in the roots of the bladder, the sum of polysaccharides in terms of fructose and the sum of extractive substances extracted by water was conducted according to pharmacopeic methods. The total amount of gravimetrically precipitated water-soluble polysaccharides was determined by a previously developed and validated patented procedure. Correlation coefficients were analyzed to examine in detail the effects of heavy metals and arsenic on the accumulation of biologically active substances. Of the samples examined, some do not meet the requirements of the regulatory documentation for arsenic content. Significant physiological barriers have been identified to the accumulation of ecotoxicants in the roots of common burdock, which is especially noticeable for elements such as lead, mercury, arsenic, cadmium, cobalt and chromium. The raw material can selectively concentrate copper and zinc. In eight samples prepared under urbocenosis conditions, this indicator was below the minimum numerical value. Low correlation of the content of large sum of gravimetrically determined polysaccharides and extractive substances in samples of burdock roots was revealed. extracted with water, containing heavy metals and arsenic, wherein the numerical value of the sum of the polysaccharides in terms of fructose is largely dependent on the concentration of toxic elements in the plant; which is probably due to the formation of strong metal-monosaccharide complexes, which make it difficult to obtain colored complexes of monomer sugars with a complexing agent during spectrophotometric determination.
Downloads
Metrics
References
Velikanova N.A. Ekologicheskaya otsenka sostoyaniya lekarstvennogo rastitel'nogo syr'ya (na primere Polygonum aviculare L. i Plantago major L.) v urbousloviyakh goroda Voronezha i yego okrestnostey: avtoref. dis. ... kand. biol. nauk. [Ecological assessment of the state of medicinal plant raw materials (using the example of Polygonum aviculare L. and Plantago major L.) in the urban conditions of the city of Voronezh and its environs: abstract of thesis. dis. ...cand. biol. Sci.]. Voronezh, 2013, 21 p. (in Russ.).
D'yakova N.A., Slivkin A.I., Gaponov S.P., Samylina I.A. Vestnik Voronezhskogo gosudarstvennogo universiteta. Seriya: Khimiya, Biologiya, Farmatsiya, 2019, no. 3, pp. 73–78. (in Russ.).
D'yakova N.A., Slivkin A.I., Gaponov S.P. Razrabotka i registratsiya lekarstvennykh sredstv, 2019, no. 8(1), pp. 73–77. DOI: 10.33380/2305-2066-2019-8-1-73-77. (in Russ.).
D'yakova N.A. Vestnik IrGSKhA, 2019, no. 95, pp. 19–30. (in Russ.).
Lin S.C., Lin C.H., Lin C.C., Lin Y.H., Chen C.F., Chen I.C., Wang L.Y.J. Journal of Biomedical Science, 2002, vol. 9(5), pp. 401–409. DOI: 10.1007/BF02256533.
Nascimento B.A.C., Gardinassi L.G., Silveira I.M.G., Gallucci M.G., Tom M.A., Oliveira J.F.D., Moreira M.R.A., Meirelles A.F.G, Faccioli L.H., Silva C.T., Zoccal K.F. Medicines, 2019, vol. 6(3), p. 81. DOI: 10.3390/medicines6030081.
Tang Y., Lou Z., Yang L., Wang H. European Food Research and Technology, 2015, vol. 240, pp. 1203–1209. DOI: 10.1007/s00217-015-2423-0.
Chan Y.S., Cheng L.N., Wu J.H., Chan E., Kwan Y.W., Lee S.M.Y., Leung G.P.H., Yu P.H.F., Chan S.W. Inflam-mopharmacology Actions, 2011, vol. 19(5), pp. 245–254. DOI: 10.1007/s10787-010-0062-4.
Annunziata G., Barrea L., Ciampaglia R. Phytotherapy Research, 2019, vol. 33(9), pp. 2213–2220. DOI: 10.1002/ptr.6416.
Kardosova A., Ebringerova A. International Journal of Biological Macromolecules, 2003, vol. 33, pp. 135–140. DOI: 10.1016/S0141-8130(03)00079-5.
D'yakova N.A., Samylina I.A., Slivkin A.I., Gaponov S.P., Myndra A.A., Shushunova T.G. Khimiko-farmatsevticheskiy zhurnal, 2015, no. 9, pp. 35–38. DOI: 10.30906/0023-1134-2015-49-9-35-38. (in Russ.).
Kurkin V.A. Farmakognoziya. [Pharmacognosy]. Samara, 2004, 1179 p. (in Russ.).
Carlotto J., de Souza L.M, Baggio C.H., de P Werner M.F., Maria-Ferreira D., Sassaki G.L., Iacomini M., Cipria-ni T.R. International Journal of Biological Macromolecules, 2016, vol. 91, pp. 954–960. DOI: 10.1016/j.ijbiomac.2016.06.033.
Mkrtchian T.A., Snapian G.G., Nikogosian G.A. Ukrainian Biochemical Journal, 1998, vol. 1, pp. 98–105.
Al-Snafi A.E. International Journal for Pharmaceutical Research Scholars, 2014, vol. 3, pp. 663–670.
Wang H.Y., Yang J.S., Pao Y.H. Acta Pharmaceutica Sinica, 1993, vol. 28, pp. 911–917.
Kolomiyets N.E., Boyev R.S., Zhalnina L.V., Tikhomirova V.A., Kashapov D.R., Bondarchuk R.A., Novozheyeva T.P., Abramets N.Yu., Safronov S.M., Ali A.K.Kh. Khimiya rastitel'nogo syr'ya, 2021, no. 2, pp. 29–57. DOI: 10.14258/jcprm.2021028315. (in Russ.).
Gosudarstvennaya farmakopeya Rossiyskoy Federatsii. XIV izdaniye. [State Pharmacopoeia of the Russian Federation. XIV edition]. Moscow, 2018, vol. 4, 1883 p. (in Russ.).
Gosudarstvennaya farmakopeya Rossiyskoy Federatsii. XIV izdaniye. [State Pharmacopoeia of the Russian Federation. XIV edition]. Moscow, 2018, vol. 2, 1449 p. (in Russ.).
Bondarchuk S.S., Bondarchuk I.S. Statobrabotka eksperimental'nykh dannykh v MS Exsel. [Statistical processing of experimental data in MS Excel]. Tomsk, 2018, 433 p. (in Russ.).
Rebrova O.Yu. Statisticheskiy analiz meditsinskikh dannykh. Primeneniye paketa prikladnykh programm STATISTICA. [tatistical analysis of medical data. Using the STATISTICA application package]. Moscow, 2000, 312 p. (in Russ.).
Copyright (c) 2024 chemistry of plant raw material
This work is licensed under a Creative Commons Attribution 4.0 International License.
This work is licensed under a Creative Commons Attribution 4.0 International License.
The authors, which are published in this journal, agree to the following conditions:
1. Authors retain the copyright to the work and transfer to the journal the right of the first publication along with the work, at the same time licensing it under the terms of the Creative Commons Attribution License, which allows others to distribute this work with the obligatory indication of the authorship of this work and a link to the original publication in this journal .
2. The authors retain the right to enter into separate, additional contractual agreements for the non-exclusive distribution of the version of the work published by this journal (for example, to place it in the university depository or to publish it in a book), with reference to the original publication in this journal.
3. Authors are allowed to post their work on the Internet (for example, in a university repository or on their personal website) before and during the review process of this journal, as this may lead to a productive discussion, as well as more links to this published work.