STUDY OF THE COMPOSITION OF ORGANIC ACIDS IN THE LEAVES OF THE SEA BUCKTHORN OF THE CIR-CULAR (HIPPOPHAE RHAMNOIDES L.)
UDC 615.19.072
Abstract
Sea buckthorn (Hippophae rhamnoides L.) is a promising medicinal plant for harvesting not only fruits, but also leaves as a medicinal plant raw material (MPRМ). Leaf extracts have antioxidant, anti-inflammatory, antibacterial, antiviral, adaptogenic and immunostimulatory properties due to the complex of biologically active substances (BAS) (tannins, organic acids and flavonoids), which confirms their value as MPRM for the development of herbal medicines (HMP) on their basis. The aim of the work was to study the composition of organic acids (including amino acids) of sea buckthorn leaves of various phenological phases of the harvest. The object of the study is the dried leaves of sea buckthorn of three phenological phases of plant life (I – the phase of fruit set, II – the phase of single fruit ripening, III – the phase of mass ripening of fruits) collected on the territory of the Voronezh region and dried leaves of sea buckthorn in 2021. The objectives of the study included a comprehensive study of the composition of the fraction of organic acids in leaves (free and bound) using the methods of chemical and physicochemical analysis. The data obtained showed that, in general, the qualitative composition of the BAS of the group of acids of the studied leaf phenophases is similar to each other, but differs quantitatively. For the harvesting of this medicinal product on an industrial scale, from the point of view of the content of the total organic acids, the harvesting phase can be recommended, since early deleafing can lead to a decrease in the accumulation of valuable BAS groups in fruits – the source of the pharmacopoeial preparation «Oil of Hippophaës».
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Mel'nikov O.M., Vereshchagin A.L., Koshelev Yu.A. Khimiya Rastitel'nogo Syr'ya, 2010, no. 2, pp. 113–116. (in Russ.).
Kukina T.P., Shcherbakov D.N., Gen'sh K.V., Tulysheva Ye.A., Sal'nikova O.I., Grazhdannikov A.Ye., Koloso-va Ye.A. Khimiya Rastitel'nogo Syr'ya, 2016, no. 1, pp. 37–42. DOI: 10.14258/jcprm.2016011100. (in Russ.).
Jaroszewska A., Biel W. Chilean journal of agricultural research, 2017, vol. 77(2), pp. 155–162. DOI: 10.4067/S0718-58392017000200155.
Criste A., Urcan A.C., Bunea A., Furtuna F.R.P., Olah N.K., Madden R.H., Corcionivoschi N. Molecules, 2020, vol. 25(5), article 1170. DOI: 10.3390/molecules25051170.
Dharam P.A., Amrit K.S., Jyoti K., Tanveer N. Indo Global Journal of Pharmaceutical Sciences, 2012, vol. 2(2), pp. 108–113.
Saggu S., Divekar H.M., Gupta V., Sawhney R.C., Banerjee P.K., Kumar R. Food Chem Toxicol., 2007, vol. 45(4), pp. 609–617. DOI: 10.1016/j.fct.2006.10.008.
Tkacz K., WojdyłoIgor A., Turkiewicz P., Nowicka P. Journal of Food Composition and Analysis, 2021, vol. 103, arti-cle 104107. DOI: 10.1016/j.jfca.2021.104107.
Usha T., Middha S.K., Goyal A.K., Karthik M., Manoj D., Faizan S., Goyal P., Prashanth H., Pande V. The Journal of Biomedical Research, 2014, vol. 28(5), pp. 406–415. DOI: 10.7555/JBR.28.20130110.
Vijayaraghavan R., Gautam A., Kumar O., Pant S.C., Sharma M., Singh S., Kumar H.T., Singh A.K., Nivsarkar M., Kaushik M.P., Sawhney R.C., Chaurasia O.P., Prasad G.B. Indian Journal of Experimental Biology, 2006, vol. 44(10), pp. 821–831.
Murzakhmetova M.K. et al. Actualscience, 2015, vol. 1, no. 5(5), pp. 26–28. (in Russ.).
Tsybikova D.Ts., Rasputina D.B., Zalykeyeva D.N. Biologiya, khimiya i farmakologiya oblepikhi. [Biology, chemistry and pharmacology of sea buckthorn]. Novosibirsk, 1983, pp. 107–110. (in Russ.).
Chukayev S.A., Rodnayeva O.A. Byulleten' Vostochno-Sibirskogo nauchnogo tsentra Sibirskogo otdeleniya Rossiyskoy akademii meditsinskikh nauk, 2009, no. 2(66), pp. 140–142. (in Russ.).
Osmolovskaya N.G., Kuchayeva L.N., Novak V.A. Fiziologiya rasteniy, 2007, vol. 54, no. 3, pp. 381–388. (in Russ.).
Bayraktar V. Biotechnologia Acta, 2013, vol. 6, no. 3, pp. 97–106.
Kretovich V.L. Biokhimiya rasteniy. [Plant biochemistry]. Moscow, 1986, 503 p. (in Russ.).
Arnal-Schnebellen B. Entsiklopediya lekarstvennykh rasteniy. [Encyclopedia of medicinal plants]. Reader’s Digest, 2004, 351 p. (in Russ.).
Valiyeva N.G. Uchenyye zapiski Kazanskoy gosudarstvennoy akademii veterinarnoy meditsiny im. N.E. Baumana, 2010, vol. 203, pp. 44–48.
Gosudarstvennaya farmakopeya SSSR XI izd. [State Pharmacopoeia of the USSR XI ed.]. Moscow, 1990, vol. 2, pp. 147–148. (in Russ.).
Gosudarstvennaya farmakopeya Rossiyskoy Federatsii. XIV izd. [State Pharmacopoeia of the Russian Federation. XIV ed.]. Moscow, 2018. URL: http://femb.ru/femb/pharmacopea.php (in Russ.).
Trineyeva O.V., Rudaya M.A., Slivkin A.I., Safonova Ye.F. Khimiya Rastitel'nogo Syr'ya, 2019, no. 1, pp. 139–146. (in Russ.).
Trineyeva O.V., Slivkin A.I., Dmitriyeva A.V. Razrabotka i registratsiya lekarstvennykh sredstv, 2014, no. 9, pp. 136–142. (in Russ.).
Trineyeva O.V., Rudaya M.A., Slivkin A.I., Dubovitskikh M.A. Sorbtsionnyye i khromatograficheskiye protsessy, 2020, vol. 2, no. 2, pp. 277–283. (in Russ.).
Trineyeva O.V., Rudaya M.A., Slivkin A.I. Razrabotka i registratsiya lekarstvennykh sredstv, 2019, vol. 8, no. 1, pp. 38–42. (in Russ.).
Geiss F. Osnovy tonkosloynoy khromatografii. [Fundamentals of thin layer chromatography]. Moscow, 1999, 405 p. (in Russ.).
Kirkhner Yu. Tonkosloynaya khromatografiya. [Thin layer chromatography]. Moscow, 1981, pp. 402–407. (in Russ.).
Rudakov O.V., Vostrov I.A., Fedorov S.V. Sputnik khromatografista. Metody zhidkostnoy khromatografii. [The chro-matographer's companion. Liquid chromatography methods]. Voronezh, 2004, 528 p. (in Russ.).
Sharshunova M., Shvarts V., Mikhalets Ch. Tonkosloynaya khromatografiya v farmatsii i klinicheskoy biokhimii. [Thin-layer chromatography in pharmacy and clinical biochemistry]. Moscow, 1980, vol. 2, 610 p. (in Russ.).
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