STUDIES ON THE DEVELOPMENT OF THE METHODIC OF STANDARDIZATION OF LEAVES OF CRATAEGUS SANGUINEA PALL.

  • Владимир (Vladimir) Александрович (Aleksandrovich) Куркин (Kurkin) Samara State Medical University http://orcid.org/0000-0002-7513-9352 Email: Kurkinvladimir@yandex.ru
  • Татьяна (Tat'jana) Владимировна (Vladimirovna) Морозова (Morozova) Samara State Medical University Email: tanyfrost@mail.ru
  • Ольга (Ol'ga) Евгеньевна (Evgen'evna) Правдивцева (Pravdivtseva) Samara State Medical University Email: pravdivtheva@mail.ru
Keywords: genus Crataegus L., hawthorn, Crataegus sanguinea Pall., hawthorn’s leaves, hyperoside, flavonoids, spectrophotometry

Abstract

Hawthorn blood-red (Crataegus sanguinea Pall., the family Rosaceae) spreads widely in the Russian Federation. Wherein just flowers and fruits of hawthorn are used as cardiotonic medicines in the medical practice of our country. Hawthorn blood-red leaves are the perspective herbal materials, leaves contain flavonoids ((hyperoside, rhamnoside of vitexin, etc.), ascorbic acid and tannins. The gathering leaves is less time-consuming, unlike the collecting of flowers and fruits, another undoubted advantage of the leaves is long period of gathering raw material. It should be noted that hawthorn leaves together with flowers are used in foreign medicine.

The methodic of quantitative analysis of total flavonoids (calculated on hyperoside) in the Crataegus sanguinea Pall. leaves was carried out. There was determined, that 70% ethanol is optimal extragent. There were studied the dynamics and the level of accumulation of the total flavonoids in the leaves of hawthorn blood-red, which were collected during growing season 2015. The highest content of flavonoids in the leaves of hawthorn blood-red (1,59 ± 0,04%) has been noted in May during the flowering time.

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Author Biographies

Владимир (Vladimir) Александрович (Aleksandrovich) Куркин (Kurkin), Samara State Medical University
заведующий кафедрой фармакогнозии с ботаникой и основами фитотерапии, профессор, доктор фармацевтических наук, тел. (846) 260-33-59
Татьяна (Tat'jana) Владимировна (Vladimirovna) Морозова (Morozova), Samara State Medical University
интерн кафедры фармакогнозии с ботаникой и основами фитотерапии
Ольга (Ol'ga) Евгеньевна (Evgen'evna) Правдивцева (Pravdivtseva), Samara State Medical University
доцент кафедры фармакогнозии с ботаникой и основами фитотерапии

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Published
2017-03-21
How to Cite
1. Куркин (Kurkin)В. (Vladimir) А. (Aleksandrovich), Морозова (Morozova)Т. (Tat’jana) В. (Vladimirovna), Правдивцева (Pravdivtseva)О. (Ol’ga) Е. (Evgen’evna) STUDIES ON THE DEVELOPMENT OF THE METHODIC OF STANDARDIZATION OF LEAVES OF CRATAEGUS SANGUINEA PALL. // chemistry of plant raw material, 2017. № 3. P. 169-173. URL: http://journal.asu.ru/cw/article/view/1286.
Section
Low-molecular weight compounds