A COMPARATIVE STUDY OF THE COMPONENT COMPOSITION OF THE HERBS OF SOME SPECIES OF THE GENUS ACHILLEA L.

UDК 615.322

  • Anastasia Igorevna Vaskova Samara State Medical University Email: a.i.vaskova@samsmu.ru
  • Ирина Владимировна Соколова Samara State Medical University Email: i.v.sokolova@samsmu.ru
  • Vladimir Aleksandrovich Kurkin Samara State Medical University http://orcid.org/0000-0002-7513-9352 Email: Kurkinvladimir@yandex.ru
Keywords: yarrow, Achillea, herbs, flavonoids, phenylpropanoids, high performance liquid chromatography, spectrophotometry

Abstract

The article presents the results of a comparative study of the component composition of herbs of some species of the genus Achillea L. growing in the Samara region - common yarrow (Achillea millefolium L.), cartilaginous yarrow (Achillea cartilaginea (Ledeb. ex Rchb.) and noble yarrow (Achillea nobilis (L.). Spectrophotometry and high performance liquid chromatography were used as methods of investigation.

As a result of comparative spectrophotometric analysis of water-alcoholic extracts of common yarrow herbs, yarrow cartilaginous herbs and noble yarrow herbs revealed that the absorption curve of their UV spectra is due mainly to hydroxycinnamic alcohols, in particular chlorogenic and caffeic acids (290 sh. and 330 nm). When aluminum (III) chloride solution was added to the water-alcoholic extracts of yarrow herb from the studied species, a bathochromic shift of the long-wave band at 400 nm was observed due to the flavonoids.

The content of total flavonoids in the plant raw material is: common yarrow - 0.68±0.01%, cartilaginous yarrow - 0.65±0.02%, noble yarrow - 0.69±0.02%.

Chlorogenic acid, cynaroside, cosmosiin, apigenin and luteolin were identified in water-alcoholic extracts from the above described species using HPLC method. In addition, the presence of caffeic acid was detected in the water-alcoholic extracts of noble yarrow herbs.

The content of cosmosiin in the plant raw material is: common yarrow - 0.61±0.01%, cartilaginous yarrow - 0.56±0.02%, noble yarrow - 0.62±0.02%.

The results of the study can be used in the development of regulatory documentation for medicinal plant material "Yarrow herb" for inclusion in the State Pharmacopoeia of the Russian Federation.

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Author Biographies

Anastasia Igorevna Vaskova , Samara State Medical University

postgraduate student of the Department of Pharmacognosy with Botany and the Basics of Phytotherapy

Ирина Владимировна Соколова, Samara State Medical University

chief specialist of the scientific and educational center "Pharmacy"

Vladimir Aleksandrovich Kurkin , Samara State Medical University

Head of the Department of Pharmacognosy with Botany and Basics of Herbal Medicine, Doctor of Pharmaceutical Sciences

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Published
2024-02-14
How to Cite
1. Vaskova A. I., Соколова И. В., Kurkin V. A. A COMPARATIVE STUDY OF THE COMPONENT COMPOSITION OF THE HERBS OF SOME SPECIES OF THE GENUS ACHILLEA L. // chemistry of plant raw material, 2024. № 1. P. 140-147. URL: http://journal.asu.ru/cw/article/view/13002.
Section
Low-molecular weight compounds