COMPARATIVE PHYTOCHEMICAL STUDY OF BUDS AND BARK OF SOME SPECIES OF THE GENUS CRATAEGUS L.

UDC 615.322: 547.9 + 543.544

  • Vladimir Aleksandrovich Kurkin Samara State Medical University http://orcid.org/0000-0002-7513-9352 Email: Kurkinvladimir@yandex.ru
  • Yulia Andreevna Angreeva Samara State Medical University Email: andreevaaya@yandex.ru
  • Olga Evgenievna Pravdivtseva Samara State Medical University Email: o.e.pravdivtseva@samsmu.ru
  • Alina Valitovna Zhdanova Samara State Medical University Email: a.v.zhdanova@samsmu.ru
  • Anna Samara State Medical University Email: kurkina-av@yandex.ru
  • Tatjana Samara National Research University named after academician S.P. Korolev Email: tanya.zhavkina@yandex.ru
  • Tatjana Scientific Society "Professional Association of Natural Therapists" Email: KiselevaTL@yandex.ru
Keywords: Crataegus sanguinea Pall., Crataegus submollis Sarg., Crataegus flabellata (Bosc ex Spach) K. Koch, hawthorn bark, hawthorn buds, flavonoids, TLC, spectrophotometry

Abstract

The cultivation of plants of the genus Crataegus L., (Rosaceae family) is associated with constant pruning of plant branches, which can be carried out in early spring. At the same time, a large amount of phytomass is formed, which is lignified shoots with buds that are not currently used. Not only official Crataegus sanguinea Pall. are cultivated on the territory of the Russian Federation, but North American species such as Crataegus submollis Sarg. and Crataegus flabellata (Bosc ex Spach) K.Koch. The aim of the study is a comparative phytochemical study of the composition of the kidneys and bark of some species of the genus Crataegus L. Buds and bark of Crataegus sanguinea Pall., Crataegus submollis Sarg. and Crataegus flabellata (Bosc ex Spach) K. Koch were harvested in early April 2023 on the territory of the Botanical Garden of Samara University. The air-dried buds and bark were examined by thin-layer chromatography on plates "Sorbfil". The quantitative content of the sum of flavonoids was determined using direct spectrophotometry in the case of analysis of reduced forms of flavonoids and differential spectrophotometry in the case of analysis of oxidized forms of flavonoids. As a result of the study conducted by thin-layer chromatography, it was possible to detect flavonoids in the bark and buds of all the studied hawthorn species. The buds and bark of the Crataegus flabellata (Bosc ex Spach) K. Koch prevail in the content of reduced forms of flavonoids, which is 20.00±0.89% and 13.27±0.59%. The buds and bark of some wild and cultivated hawthorn species contain significant amounts of both reduced and oxidized forms of flavonoids and may be suitable for medical use.

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Author Biographies

Vladimir Aleksandrovich Kurkin , Samara State Medical University

Head of the Department of Pharmacognosy with Botany and Fundamentals of Phytotherapy, Doctor of Pharmaceutical Sciences, Professor

Yulia Andreevna Angreeva, Samara State Medical University

postgraduate student of the Department of Pharmacognosy with Botany and the Basics of Phytotherapy

Olga Evgenievna Pravdivtseva , Samara State Medical University

Professor of the Department of Pharmacognosy with Botany and Fundamentals of Phytotherapy

Alina Valitovna Zhdanova, Samara State Medical University

Associate Professor of the Department of Fundamental and Clinical Biochemistry with Laboratory Diagnostics

Anna, Samara State Medical University

Head of the Department of Pharmaceutical Technology with a Course in Biotechnology

Tatjana, Samara National Research University named after academician S.P. Korolev

начальник отдела дендрологии Ботанического сада Самарского университета

Tatjana, Scientific Society "Professional Association of Natural Therapists"

Director of the Research Center, President

References

Gosudarstvennaya Farmakopeya Rossiyskoy Federatsii. XIV izd. [State Pharmacopoeia of the Russian Federation. XIV edition]. Moscow, 2018. URL: http://femb.ru/femb/pharmacopea.php. (in Russ.).

Kurkina A.V. Flavonoidy farmakopeynykh rasteniy: monografiya. [Flavonoids of pharmacopoeial plants: monograph]. Samara, 2012, 290 p. (in Russ.).

Kurkin V.A., Morozova T.V., Zaytseva Ye.N., Pravdvitseva O.Ye., Volkova N.A., Gamirova G.F. Okhrana truda i tekhnika bezopasnosti v uchrezhdeniyakh zdravookhraneniya, 2017, no. 11, pp. 29–35. (in Russ.).

Kurkin V.A., Volkova N.A., Pravdivtseva O.Ye., Zaytseva Ye.N., Tsibina A.S., Klimova A.I. Nauka i innovatsii v meditsine, 2022, vol. 7, no. 3, pp. 202–205. DOI: 10.35693/2500-1388-2022-7-3-202-205. (in Russ.).

Morozova T.V., Kurkina A.V., Pravdivtseva O.Ye., Dubishchev A.V. Izvestiya Samarskogo nauchnogo tsentra RAN, 2015, vol. 17, no. 5(3), pp. 959–963. (in Russ.).

Morozova T.V., Kurkin V.A., Dubishchev A.V., Kurkina A.V., Pravdivtseva O.Ye., Volkova N.A. Farmatsiya, 2017, vol. 66, no. 4, pp. 37–39. (in Russ.).

European Pharmacopoeia, 8-th ed. Strasbourg, 2014, vol. 1, 1456 p.

Gosudarstvennaya Farmakopeya Respubliki Belarus'. [State Pharmacopoeia of the Republic of Belarus]. Minsk, 2007, vol. 2, 471 p. (in Russ.).

Derev'ya i kustarniki SSSR. [Trees and shrubs of the USSR]. Moscow; Leningrad, 1954, vol. 3, 872 p. (in Russ.).

urkin V.A., Pravdivtseva O.Ye., Shaykhutdinov I.Kh., Kurkina A.V., Zaytseva Ye.N., Volkova N.A. Vidy roda bo-yaryshnik (Crataegus L.): standartizatsiya i sozdaniye lekarstvennykh preparatov: monografiya. [Species of the genus hawthorn (Crataegus L.): standardization and creation of medicinal products. Monograph]. Samara, 2020, 118 p. (in Russ.).

Kurkin V.A., Volkova N.A., Pravdivtseva O.Ye. Farmatsevticheskoye delo i tekhnologiya lekarstv, 2022, no. 1, pp. 26–31. DOI: 10.33920/med-13-2202-03. (in Russ.).

Morozova T.V., Volkova N.A., Kurkin V.A., Pravdivtseva O.Ye., Rozno S.A., Zhavkina T.M. Vestnik Permskoy gosudarstvennoy farmatsevticheskoy akademii, 2017, no. 19, pp. 204–205. (in Russ.).

Rastitel'nyye resursy SSSR: Tsvetkovyye rasteniya, ikh khimicheskiy sostav, ispol'zovaniye; Semeystva Hy-drangeaceae – Haloragaceae. [Plant resources of the USSR: Flowering plants, their chemical composition, use; Families Hydran-geaceae – Haloragaceae]. Leningrad, 1987, pp. 34–42. (in Russ.).

Kurkin V.A., Morozova T.A., Pravdivtseva O.Ye. Khimiya rastitel'nogo syr'ya, 2017, no. 3, pp. 169–173. DOI: 10.14258/jcprm.2017031286. (in Russ.).

Morozova T.V., Kurkin V.A., Pravdivtseva O.Ye., Rozno S.A., Zhavkina T.M. Aspirantskiy vestnik Povolzh'ya, 2018, no. 1-2, pp. 22–24. DOI: 10.17816/2075-2354.2018.18.22-24. (in Russ.).

Sagaradze V.A. Farmakognosticheskoye issledovaniye i standartizatsiya perspektivnogo lekarstvennogo rasti-tel'nogo syr'ya – «Tsvetki s list'yami» vidov roda Boyaryshnik (Crataegus L.) flory Rossiyskoy Federatsii: avtoref. dis. … kand. farm. nauk. [Pharmacognostic study and standardization of promising medicinal plant raw materials – “Flowers with leaves” of species of the genus Hawthorn (Crataegus L.) of the flora of the Russian Federation: author's abstract. diss. … candidate of pharm. sciences]. Moscow, 2019, 24 p. (in Russ.).

Kurkin V.A., Volkova N.A., Pravdivtseva O.Ye., Trifonova P.V., Varina N.R., Stenyayeva V.V., Dubishchev A.V., Agapov A.I. Traditsionnaya meditsina, 2022, no. 3(69), pp. 42–46. DOI: 10.54296/18186173_2022_3_42. (in Russ.).

Volkova N.A. Farmakognosticheskoye issledovaniye syr'ya predstaviteley roda Crataegus L. kak perspektiv-nogo istochnika biologicheski aktivnykh soyedineniy: avtoref. dis. … kand. farm. nauk. [Pharmacognostic study of raw mate-rials of representatives of the genus Crataegus L. as a promising source of biologically active compounds: author's ab-stract. diss. … candidate of pharmaceutical sciences]. Samara, 2023, 23 p. (in Russ.).

Shaykhutdinov I.Kh. Issledovaniye po standartizatsii lekarstvennykh rastitel'nykh preparatov na osnove sy-r'ya vidov roda Boyaryshnik (Crataegus L.): avtoref. dis. … kand. farm. nauk. [Research on standardization of herbal medicines based on raw materials of species of the genus Hawthorn (Crataegus L.): author's abstract. dis. … candidate of pharma-ceutical sciences]. Samara, 2021, 24 p. (in Russ.).

Morozova T.V. Farmakognosticheskoye issledovaniye nekotorykh vidov roda (Crataegus L.): avtoref. dis. … kand. farm. nauk. [Pharmacognostic study of some species of the genus (Crataegus L.): author's abstract. dis. … candidate of pharma. sciences]. Samara, 2019, 24 p. (in Russ.).

Gusakova V.A. Fitokhimicheskoye izucheniye i perspektivy ispol'zovaniya boyaryshnika myagkovatogo (Crataegus submollis Sarg.): avtoref. dis. … kand. farm. nauk. [Phytochemical study and prospects for the use of soft hawthorn (Crataegus submollis Sarg.): author's abstract. dis. … candidate of pharmaceutical sciences]. Samara, 2023, 19 p. (in Russ.).

Published
2024-09-25
How to Cite
1. Kurkin V. A., Angreeva Y. A., Pravdivtseva O. E., Zhdanova A. V., Kurkina A. V., Zhavkina T. M., Kiseleva T. L. COMPARATIVE PHYTOCHEMICAL STUDY OF BUDS AND BARK OF SOME SPECIES OF THE GENUS CRATAEGUS L. // chemistry of plant raw material, 2024. № 3. P. 169-176. URL: http://journal.asu.ru/cw/article/view/13495.
Section
Low-molecular weight compounds