FRUITS OF SORBUS AUCUPARIA L. ARE SOURCE DRUG FOR INCREASE OF TUMORS EFFECTIVENESS CHEM-OTHERAPY
Abstract
The composition of phenolic compounds of extracts of rowanberry (Sorbus aucuparia L.) fruit, prepared with 40% ethanol and 95% acidified ethanol was studied. Differences in the content of flavonoids, including anthocyanins, and phenolic acids have been established. It was found that the most efficiently increases the antimetastatic activity of cyclophosphamide extract of rowan fungi on 95% acidified ethanol enriched with anthocyanins. The purpose of the study was to: study the effect of hydroalcoholic extracts of rowan fungi on the development of Lewis lung carcinoma and the antitumor activity of cyclophosphamide; to reveal the most effective extract containing a phenolic complex, for further study as a promising drug.
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