CHROMATOGRAPHY-MASS SPECTROMETRIC STUDIES COMPONENT OF CHEMICAL COMPOSITION OF ES-SENTIAL OIL LAURUS NOBILIS L. ABKHAZIA
Abstract
The aim of this work is the gas chromatography-mass spectrometric investigation of the component chemical composition of essential oil of leaves of Laurus nobilis L., grown in a humid subtropical climate of the Republic. Over the last 10–15 years, published data on the high effectiveness of the essential oil as an anti-bacterial agent for a variety ryadya strains, in particular for staphylococcus c higher activity than antibiotic tetracycline; as an anti-cancer agent against a number of pathogenic cells, including against the growth of MCF7 mammary adenocarcinoma, as well as a number of other pharmaceutical applications. The dependence of the composition of the essential oil from the growing region efironosov and its pharmaceutical value determined the relevance of the work. During the study we identified 76 compounds, 74 have been identified: 48 monoterpenes (core: limonene, 1,8-cineole, linalool, sabinol, terpinen-4-ol, α-terpineol, α-terpinene acetate, eugenol, methyl eugenol) and 22 sesquiterpene (basic: caryophyllene, β-elements, caryophyllene oxide). A comparative analysis of the obtained essential oil by steam hydrodistillation and microwave (MW) hydrodistillation. The essential oil obtained by the microwave, increased content of cyclic monoterpenes. So the content of α-pinene in the hydrodistillation of 1,93%, while the microwave method, 4,72%; Sabina content of 7,12 and 12,51%, respectively. Microwave method gives a greater number of severe sesquiterpenes. And the output of individual sesquiterpenes in the microwave method can be up to 2 – 3-fold higher compared to Steam distillation. Thus, the content of caryophyllene 0,48 and 0,23%, respectively; similarly for β-eudesmola 0,06 and 0,02%. A brief literature review on the preparation and properties of essential oil of Laurus nobilis L.
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