SPECIES OF THE GENUS ALCHEMILLA L. (ROSACEAE): CHEMICAL COMPOSITION, BIOLOGICAL ACTIVITY AND USE IN MEDICINE (REVIEW)

  • Ирина (Irina) Евгеньевна (Evgenievna) Лобанова (Lobanova) Central Siberian Botanical Garden, Siberian Branch of the Russian Academy of Sciences Email: irevlob@ngs.ru
  • Галина (Galina) Ивановна (Ivanovna) Высочина (Vysochina) Central Siberian Botanical Garden, Siberian Branch of the Russian Academy of Sciences Email: vysochina_galina@mail.ru
  • Наталья (Natal'ya) Алексеевна (Alekseevna) Мазуркова (Mazurkova) State Scientific Center of Virology and Biotechnology "Vector" Email: mazurkova@vector.nsc.ru
  • Татьяна (Tat'yana) Абдулхаиловна (Abdulkhailovna) Кукушкина (Kukushkina) Central Siberian Botanical Garden, Siberian Branch of the Russian Academy of Sciences Email: kukushkina-phyto@yandex.ru
  • Екатерина (Ekaterina) Игоревна (Igorevna) Филиппова (Filippova) State Scientific Center of Virology and Biotechnology "Vector" Email: filipova_ei@vector.nsc.ru
Keywords: Alchemilla L., chemical composition, biological activity, use in medicine

Abstract

Data about on taxonomy of Alchemilla L.genus, distribution of Alchemilla species in world flora, use in traditional and official medicine of the different countries are presented. Questions of chemical composition, biological activity and pharmacological studying are considered. It is shown that in the last decades in Russia there is an active research of Alchemilla species at the level of regional and local floras. Species of this difficult genus in the systematic relation are offered to be used as the vegetable medicinal raw materials of different function containing compounds of different chemical classes and possessing a wide range of biological activity. As a result of complex studying with application of the latest methods of a research and standardization of vegetable raw materials a lady's mantle on existence and content of the main active ingredients 13 types of the Alchemilla species growing in Russia have been recommended for medical application. For the first time researches on antiviral activity of preparations from plant extracts of Alchemilla vulgaris L.s.I concerning some RNA - and DNA - genomic viruses are discussed. Analysis of the literature data reveals the prospects for the use of species of the genus Alchemilla.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Author Biographies

Ирина (Irina) Евгеньевна (Evgenievna) Лобанова (Lobanova), Central Siberian Botanical Garden, Siberian Branch of the Russian Academy of Sciences

кандидат биологических наук, старший  научный сотрудник

Галина (Galina) Ивановна (Ivanovna) Высочина (Vysochina), Central Siberian Botanical Garden, Siberian Branch of the Russian Academy of Sciences

доктор биологических наук, профессор, главный научный сотрудник

Наталья (Natal'ya) Алексеевна (Alekseevna) Мазуркова (Mazurkova), State Scientific Center of Virology and Biotechnology "Vector"

доктор биологических наук, заведующая лабораторией препаратов природного происхождения отдела профилактики и лечения особо опасных инфекций

Татьяна (Tat'yana) Абдулхаиловна (Abdulkhailovna) Кукушкина (Kukushkina), Central Siberian Botanical Garden, Siberian Branch of the Russian Academy of Sciences

старший научный сотрудник

Екатерина (Ekaterina) Игоревна (Igorevna) Филиппова (Filippova), State Scientific Center of Virology and Biotechnology "Vector"

научный сотрудник

References

Tikhomirov V.N. Flora Vostochnoy Yevropy. [Flora of Eastern Europe]. St. Petersburg, 2001, vol. 10, pp. 470–531. (in Russ.).

Gehrke B., Bräuchler C., Romoleroux K., Lundberg M., Heubl G., Eriksson T. Molecular Phylogenetic and Evolution, 2008, vol. 47, pp. 1030–1044. DOI: 10.1016/j.ympev.2008.03.004.

Marzieh B.F., Kobra C.K., Robabeh S.S. Taxonomy and Biosystematics, 2014, vol. 21, pp. 21–30.

Flora Tsentral'noy Sibiri. II Rozotsvetnyye – Astrovyye [Flora of Central Siberia. II Rosaceae - Astrovae], ed. L.I. Malyshev, G.A. Peshkova. Novosibirsk, 1979, 1047 p. (in Russ.).

Popov M.G. Flora Sredney Sibiri. [Flora of Central Siberia]. Moscow – Leningrad, 1957, vol. 1, 554 p. (in Russ.).

Konspekt flory Sibiri. Sosudistyye rasteniya. [Summary of the flora of Siberia. Vascular plants]. Novosibirsk, 2005, 362 p. (in Russ.).

Zhukova O.V. Populyatsionnoye issledovaniye mikrovidov manzhetki Alchemilla vulgaris L.s.I., Rosaceae: avtoref. dis. … kand. biol. nauk. [A population-based study of microvidia cuffs Alchemilla vulgaris L.s.I., Rosaceae: Abstract. dis. ... Cand. biol. sciences]. Yoshkar-Ola, 2008, 24 p. (in Russ.).

Zorina Ye.V. Farmakognosticheskoye izucheniye vidov roda Alchemilla L. Permskogo kraya: avtoref. dis. … kand. farm. nauk. [Pharmacognostic study of species of the genus Alchemilla L. Perm Territory: Abstract. dis. ... Cand. farm sciences]. Perm', 2009, 24 p. (in Russ.).

Artem'yeva V.V., Guseva Ye.A. Novyye tekhnologii, 2010, no. 1, pp. 121–124. (in Russ.).

Filimonova T.V. Analiz vidov roda Alchemilla v Murmanskoy oblasti: sistematika, geografiya, ekologiya: avtoref. dis. … kand. biol. nauk. [Analysis of the species of the genus Alchemilla in the Murmansk region: systematics, geography, ecology: author. dis. ... Cand. biol. sciences]. St. Petersburg, 2007, 24 p. (in Russ.).

Babayan M.S. Farmakognosticheskre izucheniye manzhetki trinadtsatilopastnoy: avtoref. dis. …kand. farm. nauk. [Pharmacognostic study of the thirteen-lip cuff: Author. dis. ... Cand. farm sciences]. Pyatigorsk, 2015, 24 p. (in Russ.).

Chkalov A.V. Vidovoy sostav i ekologo-tsenoticheskaya kharakteristika manzhetok Alchemilla L. v lokal'nykh florakh Nizhegorodskogo Povolzh'ya: avtoref. dis. … kand. biol. nauk. [Species composition and ecological-cenotic characteris-tics of Alchemilla L. cuffs in local floras of the Nizhny Novgorod Volga region: Author. dis. ... Cand. biol. sciences]. Nizhniy Novgorod, 2009, 24 p. (in Russ.).

Bayeva V.M. Farmakognosticheskoye izucheniye lekarstvennykh rasteniy s ispol'zovaniyem molekulyarno-biologicheskikh metodov: avtoref. dis. … dokt. farm. nauk. [Pharmacognostic study of medicinal plants using molecular biological methods: Abstract. dis. ... Dr. farm sciences]. Moscow, 2009, 48 p. (in Russ.).

Kharitontsev B.S. Problemy izucheniya rastitel'nogo pokrova Sibiri: materialy VI Mezhdunarodnoy nauchnoy konfer-entsii. [Problems of studying the plant cover of Siberia: proceedings of the VI International Scientific Conference]. Tomsk, 2017, p. 176. (in Russ.).

Glazunova K.P. Apomiksis u vostochnoyevropeyskikh predstaviteley roda Alchemilla L.: avtoref. dis. … kand. biol. nauk. [Apomixis in Eastern European representatives of the genus Alchemilla L .: Abstract. dis. ... Cand. biol. sciences]. Moskva, 1983, 24 p. (in Russ.).

Lekarstvennyye rasteniya i ikh primeneniye. [Medicinal plants and their use]. Minsk, 1974, 592 p. (in Russ.).

Dikorastushchiye lekarstvennyye rasteniya [Wild medicinal plants], ed. A.F. Gammerman, I.D. Yurkevich. Minsk, 1968, 390 p. (in Russ.).

Chopik V.I., Dudcheko L.G., Krasnova A.N. Dikorastushchiye poleznyye rasteniya Ukrainy. [Wild useful plants of Ukraine]. Kiev, 1983, 397 p. (in Russ.).

Shimanskaya V.Ye. Lekarstvennyye rasteniya narodnoy meditsiny severo-zapadnykh oblastey Ukrainskoy SSR: avtoref. dis. … kand. biol. nauk. [Medicinal plants of traditional medicine of the north-western regions of the Ukrainian SSR: author. dis. ... Cand. biol. sciences]. Lviv, 1966, 20 p. (in Russ.).

Shotadze V.Ye. Sbornik trudov Tbilisskogo nauchno-issledovatel'skiy khimiko-farmatsevticheskiy instituta. [Collected Works of the Tbilisi Chemical and Pharmaceutical Research Institute]. Tbilisi, 1960, vol. 9, pp. 119–135. (in Russ.).

Stanilova M., Gorgorov R., Trendafilova A., Nikolova M., Vitkova A. Natural Product Communications, 2012, vol. 7(6), pp. 761–766.

Hoppe H.A. Drogenkunde. Berlin; New York, 1975, vol. 1, 1311 p.

Larin I.V., Agababyan Sh.M., Rabotnov T.A., Lyubskaya A.F., Larina V.K., Kasimenko M.A. Kormovyye rasteniya senokosov i pastbishch SSSR. [Fodder plants of haymakings and pastures of the USSR]. Moscow; Leningrad, 1956, vol. 3, 879 p. (in Russ.).

Poletiko O.M., Mishenkova A.P. Dekorativnyye travyanistyye rasteniya otkrytogo grunta. [Decorative grassy plants of an open ground]. Leningrad, 1967, 207 p. (in Russ.).

Murav'yeva D.A. Uchenyye zapiski Pyatigorskogo farmatsevticheskogo institutata, 1957, vol. 2, pp. 188–197. (in Russ.).

Sedova A.B., Votinova T.I., Shestakova Yu.V. Nauchnyye trudy, 1997, vol. 36, pp. 249–255. (in Russ.).

Pavlov N.V. Rastitel'noye syr'ye Kazakhstana. [Vegetable raw materials of Kazakhstan]. Moscow, 1947, 550 p. (in Russ.).

Vays R.F., Fintel'mann F. Fitoterapiya. Rukovodstvo. [Herbal Medicine. Manual]. Moscow, 2004, 552 p. (in Russ.).

Dimins F., Mikelsone V., Kaneps M. Proceedings of the Latvian Academy of Sciences, Section B: Natural, Exact and Applied Sciences, 2013, vol. 67(4/5), pp. 433–436, DOI: 10.2478/prolas-2013-0067

Shrivastava R., John G. Clinical Drug Investigation, 2006, vol. 26(10), pp. 567–573, DOI: 10.2165/00044011-200626100-00003.

Jayanegara A., Marquardt S., Kreuzer M., Leiber F. Journal of the Science of Food and Agriculture, 2011, vol. 91(10), pp. 1863–1870, DOI: 10.1002/jsfa.4398.

Rastitel'nyye resursy SSSR. Tsvetkovyye rasteniya, ikh khimicheskiy sostav, ispol'zovaniye. T. 3. Semeystva Hydran-geaceae-Haloragaceae. [Plant resources of the USSR. Flowering plants, their chemical composition, use. Vol. 3. Families Hydrangeaceae-Haloragaceae]. Leningrad, 1987, 326 p. (in Russ.).

Nosal' M.A., Nosal' I.M. Lekarstvennyye rasteniya i sposoby ikh primeneniya v narode. [Medicinal plants and methods for their use in people]. Kiev, 1959, 256 p. (in Russ.).

Ĭordanov D., Nikolov P., Boĭchinov A. Fitoterapiya. [Phytotherapy]. Sofiya, 1970, p. 91. (in Russ.).

Fraisse D., Carnat A., Carnat A.-P., Lamaison J.-L. Annales Pharmaceutiques Francaises, 1999, vol. 57 (5), pp. 401–405.

Sokolowska-Wozniak A. Herba Polonica, 1997, vol. 43(4), pp. 388–392.

Kaya B., Menemen Y., Saltan F.Z. African Journal of Traditional, Complementary and Alternative Medicines, 2012, vol. 9 (3), pp. 418–425, DOI: 10.4314/ajtcam.v9i3.18

Chelombit'ko V.A., Ayrapetova A.Yu., Nersesyan I.A. Razrabotka, issledovaniye i marketing novoy farmatsevtich-eskoy produktsii. [Development, research and marketing of pharmaceutical products]. Pyatigorsk, 2005, no. 60, pp. 70–71. (in Russ.).

Babayan M.S., Chelombit'ko V.A. Razrabotka, issledovaniye i marketing novoy farmatsevticheskoy produktsii. [Devel-opment, research and marketing of pharmaceutical products]. Pyatigorsk, 2010, no. 65. pp. 9–11. (in Russ.).

Chelombit'ko V.A., Orlovskaya T.V., Lozovitskaya-Shcherbinina Ye.F., Shamilov A.A., Grigoryan E.R., Okhremchuk A.V., Babayan M.S. Vopr. biol., med. i farm. Khimii, 2012, no. 4, pp. 39–43. (in Russ.).

Ergene B., Bahadir A.O., Bakar F., Saltan G., Nebioglu S. Ankara Universitesi Eczacilik Fakultesi Dergisi, 2010, vol. 39 (2), pp. 145–154.

Schimmer O., Escheibach H. Pharmazie, 1997, vol. 52 (6), pp. 476–478.

Felser C., Schimmer O. Planta Med., 1999, vol. 65, no. 7, pp. 668–670, DOI: 10.1055/s-2006-960845.

Bandyukova V.A. Rastitel'nyye resursy, 1969, vol. 5, no. 4, pp. 590–600. (in Russ.).

Tuka L., Tàmaş M. Farmacia (RSR), 1977, vol. 25 (4), pp. 247–252.

Duckstein S.M., Lotter E.M., Meyer U., Lindequist U., Stintzing F.C. Zeitschrift fuer Naturforschung, C: Journal of Biosciences, 2012, vol. 67(11/12), pp. 529–540, DOI: 10.1515/znc-2012-11-1201

Trendafilova A., Todorova M., Nikolova M., Gavrilova A., Vitkova A. Natural Product Communications, 2011, vol. 6 (12), pp. 1851–1854.

Trendafilova A, Todorova M., Gavrilova A., Vitkova A. Biochemical Systematics and Ecology, 2012, vol. 43, pp. 156–158. DOI: 10.1016/j.bse.2012.03.013.

Nikolova M., Dincheva I., Vitkova A., Badjakov I. Intern. J. Pharm. Sciences and Research, 2012, vol. 3 (3), pp. 802–804.

Kukenov M.K. Flavonoidosoderzhashchiye rasteniya yugo-vostoka Kazakhstana. [Flavonoid plants in the southeast of Kazakhstan]. Alma-Ata, 1984, 216 p. (in Russ.).

Iskakova B.A., Rakhmadiyeva S.B., Yerzhanova M.S. Tez. mezhvuz. konf.-konkursa mol. uchen. i spets. Kaz. gos. un-ta im. S.M. Kirova. Ch. 1. [Abstracts of the interuniversity conference-competition of young scientists and specialists of Kazakhstan State University. C.M. Kirov. Part 1]. Alma-Ata, 1990, p. 141. (in Russ.).

Iskakova B.A., Rakhimov K.D., Rakhmadiyeva S.B., Yerzhanova M.S. 8-aya Konf. mol. uchenykh - khimikov Irkut. un-ta: tez. dokl. [8th Conf. Young scientists-chemists of Irkutsk University. Theses of reports]. Irkutsk, 1990, p. 78. (in Russ.).

Iskakova B.A., Rakhmadieva S.B., Erzhanova M.S. Khimiya Prirodnykh Soedinenii, 1991, vol. 6, pp. 853–854.

Bandyukova V.A., Shynkarenko A.L. Farmatsevtycheskyy zhurnal, 1965, no. 6, pp. 37–41. (in Russ.).

Vogl H. Monatsh, 1923, vol. 44, pp. 19–28.

Schneider R. Ber. scwheiz. botan. Ges., 1950, vol. 60, pp. 244–315.

Mikhaylova V.P., Lushpa O.U. Lekarstvennyye rasteniya Kazakhstana. [Medicinal plants of Kazakhstan]. Alma-Ata, 1966, pp. 139–152. (in Russ.).

Artem'yeva V.V., D'yakova I.N., Bochkareva I.I. Vestn. Adygeyskogo gos. universiteta, 2016, no. 1 (176), pp. 94–98. (in Russ.).

Bate-Smith E.C. Bot. J. Linn. Soc., 1962, vol. 58 (371), pp. 95–173.

Krzaczek T. Farm. pol., 1984, vol. 40 (8), pp. 475–477.

Hrytsyk L.M., Tuchak N.I., Hrytsyk A.R. Farmatsevtycheskyy zhurnal, 2013, no. 3, pp. 83–87. (in Russ.).

Kaya B., Menemen Y., Saltan F.Z. Pakistan J. of Botany., 2012, vol. 44 (2), pp. 595–597.

Ayaz F.A., Hayirlioglu-Ayaz S. Biologia, 2001, vol. 56 (4), pp. 449–453.

Zhivet'yev M.A., Rudikovskaya Ye.G., Dudareva L.V., Papkina A.V., Graskova I.A., Voynikov V.K. Rastitel'nyye resursy, 2013, vol. 49, no. 3, pp. 404–410. (in Russ.).

Kacharava N., Badridze G., Chigladze L., Kurdadze T., Chkhubianishvili E., Chanishvili S. Journal of Biological Phys-ics and Chemistry, 2011, vol. 11(3), pp. 113–117, DOI: 10.4024/15KA11A.jbpc.11.03.

Olafsdottir E.S., Omarsdottir S., Jaroszewski J.W. Biochemical Systematics and Ecology, 2001, vol. 29 (9), pp. 959–962, DOI:10.1016/S0305-1978(01)00038-2.

Wehmer C. Die Pflanzenstoffe, Jena, 1929, vol. 1, 640 p.

Sokolowska-Wozniak A., Krzaczek T. Herba Polonica, 1993, vol. 39 (4), pp. 173–178.

Hayirlioglu-Ayaz S., Beyazoglu O. Grasas y Aceites, 1999, vol. 50 (5), pp. 341–344.

Matthaus B., Oezcan M.M. Botanical Studies, 2014, vol. 55 (1), pp. 1–6, DOI: 10.1186/s40529-014-0048-4.

Smetannikova A.I. Fiziol.-biokhim. issled. rasteniy Yakutii. Dokl. yubil. nauch. Sessii [Fiziol.-biochemical. researches plants of Yakutia. Report anniversary scientific session]. 1974, pp. 152–160. (in Russ.).

Luk'yanova L.M., Markovskaya Ye.F. Yestestvennaya sreda i biologicheskiye resursy Kraynego Severa. Mat. biogeo-graf. nauch. konf. [Natural environment and biological resources of the Far North. Materials of biogeographical scien-tific conference]. 1975, pp. 13–19. (in Russ.).

Bazhanova N.V., Gevorkyan A.G. Dokl. AN ArmSSR, 1970, vol. 50, no. 2, pp. 251–257. (in Russ.).

Babayan M.S., Chelombit'ko V.A. Chemistry of Natural Compounds, 2007, vol. 43 (2), pp. 241–242.

Grytsyk L.M., Tuchak N.I., Stasiv T.G., Grytsyk A.R. Pharma Innovation, 2013, vol. 2(4), pp. 50–53.

Babayan M.S., Chelombit'ko V.A. Izv. vuzov. Sev.-Kavk. regiona. Yestestv. nauki, 2009, no. 4, pp. 68–69. (in Russ.).

Falchero L., Coppa M., Esposti S., Tava A. Journal of Essential Oil Research, 2008, vol. 20 (6), pp. 542–545, DOI: 10.1080/10412905.2008.9700084.

Falchero L., Coppa M., Esposti S., Tava A. Journal of Essential Oil Research, 2009, vol. 21(6), pp. 549–552, DOI: 10.1080/10412905.2009.9700241.

Juranovic Cindric I., Zeiner M., Pozgaj M., Silic T., Stingeder G. Journal of Trace Elements in Medicine and Biology, 2015, vol. 31, pp. 274–278, DOI: 10.1016/j.jtemb.2014.09.008.

Lesovaya ZH.S., Pisarev D.M., Novikov O.O., Romanova T.A. Nauchnyye vedomosti Belgorodskogo universiteta. Seriya Meditsina. Farmatsiya, 2010, Vol. 22 (93), no. 12/2, pp. 145–149. (in Russ.).

Kukushkina T.A., Zykov A.A., Obukhova L.A. Aktual'nyye problemy sozdaniya novykh lekarstvennykh preparatov prirodnogo proiskhozhdeniya. Mater. VII Mezhdunar. s"yezda. [Actual problems of creating new drugs of natural origin. Proceedings of the VII Intern. congress]. St. Petersburg, 2003, pp. 64–69. (in Russ.).

Bayeva V.M., Sasov S.A. Farmatsiya, 2007, no. 8, pp. 9–10. (in Russ.).

D'Agostino M., Dini I., Ramundo E., Senatore F. Phytotherapy Research, 1998, vol. 12, pp. 162–163.

Fuchs K. Zur Kenntnis der Inhaltsstoffe von Prunus spinosa L. und einiger Rosaceenarten. Dissertation. München, 1959, 230 p.

Bandyukova V.A. Rastitel'nyye resursy, 1969, vol. 5, no. 4, pp. 490–600. (in Russ.).

Fraisse D., Heitz A., Carnat A., Carnat A.P., Lamaison J.L. Fitoterapia, 2000, vol. 71 (4), pp. 463–464, DOI: 10.1016/S0367-326X(00)00145-3.

Lamaison J.L., Carnat A., Petitjean-Freytet C., Carnat A.P. Annales Pharmaceutiques Francaises, 1991, vol. 49 (4), pp. 186–189.

Dimins F., Mikelsone V., Kaneps M. Proceedings of the Latvian Academy of Sciences. Section B: Natural, Exact and Applied Sciences, 2013, vol. 67 (4/5), pp. 433–436, DOI: 10.2478/prolas-2013-0067.

Kiselova Y., Ivanova D., Chervenkov T., Gerova D., Galunska B., Yankova T. Phytotherapy Research, 2006, vol. 20 (11), pp. 961–965. DOI: 10.1002/ptr.1985.

Andreyeva V.Yu, Kalinkina G.I. Khimiya rastitel'nogo syr'ya, 2000, no. 2, pp. 79–85. (in Russ.).

Andreyeva V.Yu., Angaskiyeva A.S. Khimiya rastitel'nogo syr'ya, 2011, no. 2, pp. 149–151. (in Russ.).

Glazunova K.P., Bayeva V.M. 5-y Rossiyskiy natsional'nyy kongress "Chelovek i lekarstvo". [5th Russian National Congress "Man and Medicine"]. Moscow, 1998, p. 358. (in Russ.).

Murin I.I., Bayeva V.M. Farmatsiya, 2009, no. 7, pp. 23–25. (in Russ.).

Szentmihalyi K., Csedo K., Then M. Olaj Szappan Kozmetika, 2004, vol. 53 (1), pp. 37–40.

Geiger C., Scholz E., Rimpler H. Planta Medica., 1994, vol. 60 (4), pp. 384–385, DOI: 10.1055/s-2006-959510.

Shaldayeva T.M. Khimiya rastitel'nogo syr'ya, 2013, no. 1, pp. 239–241. (in Russ.).

Andreyeva V.Yu., Kalinkina G.I. Khimiya rastitel'nogo syr'ya, 2000, no. 1, pp. 85–88. (in Russ.).

Andreyeva V.Yu. Vliyaniye ekstrakta manzhetki obyknovennoy na morfofunktsional'nyye svoystva eritrotsitov pri ser-dechno-sosudistoy patologii: avtoref. dis. … kand. biol. nauk. [The effect of the extract of the cuff ordinary on the mor-phofunctional properties of erythrocytes in cardiovascular pathology: abstract. dis. ... Cand. biol. sciences]. Tomsk, 2001, 24 p. (in Russ.).

Graskova I.A., Dudareva L.V., Zhivet'yev M.A., Stolbikova A.V., Sokolova N.A., Voynikov V.K. Khimiya rastitel'nogo syr'ya, 2011, no. 4, pp. 223–230. (in Russ.).

Hadjieva P., Palacartcheva E., Dyulgerov A., Tzvetkova A. Bulgarian Chemistry and Industry, 2000, vol. 71(1-2), pp. 56–57.

Murin I.I. Fitokhimicheskoye i farmakologicheskoye izucheniye travy manzhetki: avtoref. dis. … kand. farm. nauk. [Phytochemical and pharmacological study of cuff grass: author. dis. ... Cand. farm sciences]. Moskva, 2011, 24 p. (in Russ.).

Trefilova M.S. Vestnik PGFA, 2009, no. 5, pp. 200–202. (in Russ.).

Baszynski T. Roczniki Nauk Rolniczych. Ser. F., 1961, vol. 74, pp. 757–762.

Virtanen A.I., Ettala T. Acta Chemica Scandinavica, 1957, vol. 11, pp. 182–184.

Beguin Ch. Pharmaceutica Acta Helvetiae, 1931, vol. 6, pp. 195–200.

Teslov C.V., Makarova L.S. Nauchnyye trudy Permsk. farmats. in-ta, 1969, pp. 217–223. (in Russ.).

Tuka L., Popescu H. Clujul med., 1979, vol. 52 (1), pp. 78–83.

Usta C., Yildirim A.B., Turker A.U. Biotechnology & Biotechnological Equipment, 2014, vol. 28 (2), pp. 306–315, DOI: 10.1080/13102818.2014.909708.

Schimmer O., Lindenbaum M. Planta Medica., 1995, vol. 61(2), pp. 141–145, DOI: 10.1055/s-2006-958034.

Iskakova B.A., Rakhmadiyeva S.B. Fitontsidy. Bakterial'nyye bolezni rasteniy. [Phytoncides. Bacterial plant diseases]. Kiev; Lviv, 1990, vol. 1, p. 101. (in Russ.).

Denev P., Kratchanova M., Ciz M., Lojek A., Vasicek O., Blazheva D., Nedelcheva P., Vojtek L., Hyrsl P. Acta Bio-chimica Polonica, 2014, vol. 61(2), pp. 359–367.

Neagu E., Paun G., Albu C., Radu G.-L. J. of the Taiwan Institute of Chemical Engineers, 2015, vol. 52, pp. 1–6, DOI: 10.1016/j.jtice.2015.01.026.

Condrat D., Szabo M.-R., Radu D., Lupea A.X. Oxidation Communications, 2009, vol. 32 (4), pp. 924–929.

Oktyabrsky O. Vysochina G., Muzyka N., Samoilova Z., Kukushkina T., Smirnova G. Journal of Applied Microbiolo-gy, 2009, vol. 106(4), pp. 1175–1183, DOI: 10.1111/j.1365-2672.2008.04083.x.

Benaiges A., Armengol R., Betes C., Girones E., Marcet P. Cosmetic News, 1997, vol. 20 (117), pp. 423–426.

Jonadet M., Meunier M.T., Villie F., Bastide J.P., Lamaison J.L. J. de Pharmacologie, 1986, vol. 17(1), pp. 21–27.

Schimmer O., Haefele F., Krueger A. Mutation Research, Genetic Toxicology Testing, 1988, vol. 206 (2), pp. 201–208, DOI: 10.1016/0165-1218(88)90161-9.

Petcu P., Andronescu E., Gheorgheci V., Cucu-Cabadaief L., Zsigmond Z. Clujul Medical., 1979, vol. 52 (3), pp. 266–270.

Khanturina G.R. Izv. Nats. Ak. nauk Resp. Kazakhstan. Ser. biol., 2010, no. 1, pp. 78–81. (in Russ.).

Lobanova I.Ye., Filippova Ye.I., Vysochina G.I., Mazurkova N.A. Rast. mir Aziatskoy Rossii, 2016, no. 2 (22), pp. 64–72. (in Russ.).

Mazurkova N.A., Filippova Ye.I., Makarevich Ye.V., Lobanova I.Ye., Vysochina G.I. Sb. nauch. trudov Vseross. konf., posvyashch. 95-letiyu so dnya rozhd. prof. A.I. Shretera. [Collection of scientific papers of the All-Russian Conf., Dedicated to the 95th anniversary of the birth of prof. A.I. Schroeter]. Moscow, 2014, pp. 30–32. (in Russ.).

Vysochina G.I., Petruk A.A., Kukushkina T.A., Lobanova I.Ye., Filippova Ye.I., Makarevich Ye.V., Mazurkova N.A. Novyye dostizheniya v khimii i khim. tekhnol. rast. syr'ya. Mat. VI Vseross. konf. s mezhdunar. uch. [New advances in chemistry and chemical technology of plant materials. Materials of the VI All-Russian Conf. with international participa-tion]. Barnaul, 2014, pp. 139–141. (in Russ.).

Filippova Ye.I., Kukushkina T.A., Lobanova I.Ye., Vysochina G.I., Mazurkova N.A. Fundamental'nyye issledovaniya, 2015, vol. 23, no. 2, pp. 5139–5144. (in Russ.).

Mazurkova N.A., Kukushkina T.A., Vysochina G.I., Ibragimova ZH.B., Lobanova I.Ye., Filippova Ye.I., Mazurkov O.Yu., Makarevich Ye.V., Shishkina L.N., Agafonov A.P. Razrabotka i registratsiya lekarstvennykh sredstv, 2016, no. 1(14), pp. 118–127. (in Russ.).

Patent 2580304 (RU). 2016. (in Russ.).

Filippova Ye.I. Byull. eksper. biologii i meditsiny, 2017, vol. 163, no. 3, pp. 359–362. (in Russ.).

Borodin Yu.I., Selyatitskaya V.G., Obukhova L.A., Pal'chikova N.A., Odintsov S.V., Kukushkina T.A. Byullyuten' eksperimental'noy biologii i meditsiny, 1999, vol. 127, no. 6, pp. 697–699, DOI: 10.1007/BF02433301. (in Russ.).

Borodin YU.I., Golovnev V.A., Goncharov A.B., Zykov A.A., Tyulyubayev A.D. Byullyuten' SO RAMN, 2003, no. 2 (108), pp. 73–80. (in Russ.).

Patent 1073966 (USSR). 1983. (in Russ.).

Patent 2128516 (RU). 1999. (in Russ.).

Zykov A.A., Golovnev V.A., Belkina O.M. Byull. Sib. otd. AMN SSSR, 2000, no. 1, pp. 63–64. (in Russ.).

Shevtsov A.R. Morfologicheskiye preobrazovaniya v selezenke krysy pri sindrome dlitel'nogo sdavlivaniya v usloviyakh korrektsii bioflavonoidami manzhetki obyknovennoy: avtoref. dis. … kand. med. nauk. [Morphological transformations in the rat spleen with prolonged squeezing syndrome under the conditions of bioflavonoid correction of the cuff ordi-nary: Abstract. dis. ... Cand. medical. sciences]. Novosibirsk, 2008, 24 p. (in Russ.).

Plotnikov M.B., Koltunov A.A., Aliyev O.I., Kalinkina G.I., Berezovskaya T.P. Tr. 1-oy Vseross. konf. po botanicheskomu resursovedeniyu. [Proceedings of the 1st All-Russian Conference on Botanical Resource Manage-ment]. St. Petersburg, 1996, p. 221. (in Russ.).

Goncharov A.B. Patomorfologicheskiye izmeneniya v regionarnykh limfaticheskikh uzlakh serdtsa pri povtornom metabolicheskom infarkte miokarda i pri yego korrektsii bioflavonoidami v eksperimente: avtoref. dis. … kand. med. nauk. [Pathomorphological changes in the regional lymph nodes of the heart during repeated metabolic myocardial in-farction and its correction by bioflavonoids in the experiment: author. dis. ... Cand. medical sciences]. Novosibirsk, 2002, 24 p. (in Russ.).

Aliyev O.I. Farmakologicheskaya korrektsiya sindroma povyshennoy vyazkosti krovi pri serdechno-sosudistoy patologii: avtoref. dis. … dokt. med. nauk. [Pharmacological correction of the syndrome of increased blood viscosity in cardiovascular pathology: Abstract. dis. ... Dr. medical sciences]. Tomsk, 2004, 48 p. (in Russ.).

Zhanayeva S.Ya. Izmeneniya lizosom pecheni krys pri intoksikatsii gerbitsidom 2,4-dikhlorfenoksiuksusnoy kislotoy i korrektsii polifenol'nym kompleksom iz list'yev manzhetki obyknovennoy (Alchemilla vulgaris L.): avtoref. dis. … kand. biol. nauk. [Changes in the lysosomes of the rat liver during intoxication with the herbicide 2,4-dichlorophenoxyacetic acid and the correction of the polyphenol complex from the cuff of the ordinary cuff (Alchemilla vulgaris L.): Abstract. dis. ... Cand. biol. sciences]. Novosibirsk, 2000, 24 p. (in Russ.).

Borodin Yu.I., Zykov A.A., Golovnev V.A., Gorchakov V.N. 5-y Ross. nats. kongr. "Chelovek i lekarstvo". [5th Rus-sian National Congress "Man and medicine"]. Moscow, 1998, p. 30. (in Russ.).

Luk'yanova Ye.S. Morfofunktsional'nyye izmeneniya pecheni i pochek v razlichnyye periody sindroma dlitel'nogo sdavlivaniya i na fone primeneniya ksenobiotikov: avtoref. dis. … dokt. med. nauk. [Morphofunctional changes in the liver and kidneys in different periods of the syndrome of prolonged compression and against the background of the use of xenobiotics: autoref. dis. ... Dr. medical sciences]. Novosibirsk, 2006, 48 p. (in Russ.).

Patent 2429852 (RU). 2011. (in Russ.).

Czgan F.Ch., Frohne D., Holtzel Ch. Teedrogen und Phytopharmaka, Stuttgart, 1997, 668 p.

Pharmacopée Française. IX Edition. 5-e suppl., Juillet, 1979.

European Pharmacopeia. Monograph., 2008, 1387 p.

Zorina Ye.V., Oleshko G.I., Sedova A.B. Farmatsiya, 2009, no. 1, pp. 11–15. (in Russ.).

Fecka I. Journal of AOAC International, 2009, vol. 92 (2), pp. 410–418.

Stern K.I. Vestnik PGFA, 2009, no. 5, pp. 196–197. (in Russ.).

Smolyakova I.M., Andreyeva V.YU., Kalinkina G.I., Avdeyenko S.N., Shchetinin P.P. Khimiko-farmatsevticheskiy zhurnal, 2011, vol. 45, no. 11, pp. 27–30. (in Russ.).

Oleshko G.I., Yarygina T.I., Zorina Ye.V., Reshetnikova M.D. Farmatsiya, 2011, no. 3, pp. 14–17. (in Russ.).

ALCHEMILLA L. (ROSACEAE)
Published
2019-03-06
How to Cite
1. Лобанова (Lobanova)И. (Irina) Е. (Evgenievna), Высочина (Vysochina)Г. (Galina) И. (Ivanovna), Мазуркова (Mazurkova)Н. (Natal’ya) А. (Alekseevna), Кукушкина (Kukushkina)Т. (Tat’yana) А. (Abdulkhailovna), Филиппова (Filippova)Е. (Ekaterina) И. (Igorevna) SPECIES OF THE GENUS ALCHEMILLA L. (ROSACEAE): CHEMICAL COMPOSITION, BIOLOGICAL ACTIVITY AND USE IN MEDICINE (REVIEW) // chemistry of plant raw material, 2019. № 1. P. 5-22. URL: http://journal.asu.ru/cw/article/view/4032.
Section
Reviews