NEW APPROACHES TO STANDARDIZATION OF CASSIA LEAVES

  • Владимир (Vladimir) Александрович (Aleksandrovich) Куркин (Kurkin) Samara State Medical University, Chapaevskaia st., 89, Samara, 443099 Email: Kurkinvladimir@yandex.ru
  • Анна (Anna) Анатольевна (Anatol'evna) Шмыгарева (Shmygareva) Samara State Medical University, Chapaevskaia st., 89, Samara, 443099 Email: a.shmygareva@mail.ru
DOI_disc_logo https://doi.org/10.14258/jcprm.201601421
Keywords: Cassia acutifolia Del., leaves anthracenderivatives, flavonoids, naphthalenes, standardization, spectrophotometry, TLC

Abstract

The expediency of the using for the determination of identity of Cassia acutifolia Del. leaves of spectrophotometry and TLC was substantiated. As the results of the chemical study of Cassia acutifolia leaves were isolated the predominant components of this plant – 1,7-dihydroxy-3-carboxyanhraquinone, 8-O-β-D-glucopyranoside of torachrysone, kaempferol-3-O-gentiobioside and on this basis the methodological approaches for standardization of Cassia acutifolia leaves were developed. These methodological approaches consist in the determination not only of anthracenderivatives, but also other diagnostic phenolic compounds, including flavonoids and naphthalenes. The concept of the method of quantitative determination of the total anthracenderivatives by means of spectrophotometry at analytical wavelength 530 nm was developed. The total anthracenderivatives contents of the in Cassia acutifolia leaves are varied with 1,21 to 1,88% (calculated on sennoside B).

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Author Biographies

Владимир (Vladimir) Александрович (Aleksandrovich) Куркин (Kurkin), Samara State Medical University, Chapaevskaia st., 89, Samara, 443099
заведующий кафедрой фармакогнозии с ботаникой и основами фитотерапии, доктор фармацевтических наук,  профессор, тел.: (846) 260-33-59
Анна (Anna) Анатольевна (Anatol'evna) Шмыгарева (Shmygareva), Samara State Medical University, Chapaevskaia st., 89, Samara, 443099
доцент кафедры фармации, кандидат фармацевтических наук

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Published
2016-02-15
How to Cite
1. Куркин (Kurkin)В. (Vladimir) А. (Aleksandrovich), Шмыгарева (Shmygareva)А. (Anna) А. (Anatol’evna) NEW APPROACHES TO STANDARDIZATION OF CASSIA LEAVES // chemistry of plant raw material, 2016. № 1. P. 71-77. URL: http://journal.asu.ru/cw/article/view/421.
Issue
No 1 (2016)
Section
Low-molecular weight compounds

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