COMPARATIVE PHYTOCHEMICAL STUDY OF THE AERIAL PARTS OF THE WILD-GROWING AND CULTIVAT-ED CHICORY ORDINARY (CICHORIUM INTYBUS L.)

UDC 615.322

  • Ol'ga Leonidovna Saybel All-Russian Scientific Research Institute of Medicinal and Aromatic Plants Email: olster@mail.ru
  • Andrey Ivanovich Radimich All-Russian Research Institute of Medicinal and Aromatic Plants Email: vilarnii.radimich@mail.ru
  • Grigoriy Vasil'yevich Adamov All-Russian Research Institute of Medicinal and Aromatic Plants Email: grig.adamov@mail.ru
  • Tamara Darizhapovna Dargaeva All-Russian Research Institute of Medicinal and Aromatic Plants Email: olster@mail.ru
Keywords: chicory, hydroxycinnamic acids, coumarins, flavonoids, HPLC-UV, HPLC-MS

Abstract

The search for new plant species that are promising for use as a source of biologically active substances is an actual area of scientific research in the field of chemistry of natural compounds. The object of this study is the chicory (Cichorium intybus L.)

The purpose of our scientific research is to conduct a comparative phytochemical study of the aerial parts of wild-growing and cultivated chicory to establish differences in the qualitative composition and content of secondary metabolites.

As a result of studies by HPLC-MS, in the aerial part of a wild-growing plant, 10 compounds were identified esculletin, chicoriin, chicoric acid, chlorogenic acid, kaftaric acid, isochlorogenic A acid, caffeic acid, isoquercetin, astragalin, rutin. The dominant group of substances are oxycoumarins. The phenolic complex of the cultivated plant has a similar composition of secondary metabolites, however, its derivatives are hydroxycinnamic acid derivatives.

The quantitative content of phenolic compounds in the wild-growing chicory herb was 2.56±0.12%, cultivated – 4.14±0.21%.

Significant differences in the content and qualitative composition of phenolic compounds make it possible to use the chicory of a wild-growing and cultivated population to obtain pharmaceutical substances with various pharmacological effects.

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Author Biographies

Ol'ga Leonidovna Saybel, All-Russian Scientific Research Institute of Medicinal and Aromatic Plants

кандидат фармацевтических наук, руководитель центра химии и фармацевтической технологии

Andrey Ivanovich Radimich, All-Russian Research Institute of Medicinal and Aromatic Plants

старший научный сотрудник отдела фитохимии и стандартизации

Grigoriy Vasil'yevich Adamov, All-Russian Research Institute of Medicinal and Aromatic Plants

научный сотрудник лаборатории атомарно-молекулярной биорегуляции и селекции

Tamara Darizhapovna Dargaeva, All-Russian Research Institute of Medicinal and Aromatic Plants

доктор фармацевтических наук, профессор, главный научный сотрудник отдела фитохимии и стандартизации

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Published
2020-10-22
How to Cite
1. Saybel O. L., Radimich A. I., Adamov G. V., Dargaeva T. D. COMPARATIVE PHYTOCHEMICAL STUDY OF THE AERIAL PARTS OF THE WILD-GROWING AND CULTIVAT-ED CHICORY ORDINARY (CICHORIUM INTYBUS L.) // chemistry of plant raw material, 2020. № 3. P. 187-195. URL: http://journal.asu.ru/cw/article/view/7386.
Section
Low-molecular weight compounds