USE OF ULTRASOUND FOR EXTRACTION OF BIOLOGICALLY ACTIVE SUBSTANCES FROM TAMARIX HISPI-DA WILLD.

UDC 547. 972

  • Shynar Nurlanovna Zhumagaliyeva Al-Farabi Kazakh National University Email: shynarnur@mail.ru
  • Arailym Amanzholkyzy Al-Farabi Kazakh National University Email: arailymamanzholkyzy13@gmail.com
  • Nurgul Adaybaevna Sultanova Al-Farabi Kazakh National University Email: nureu@mail.ru
  • Zharylkasyn Abduakhitovich Abilov Al-Farabi Kazakh National University Email: abilovs51@mail.ru
DOI_disc_logo https://doi.org/10.14258/jcprm.2021038695
Keywords: ultrasonic extraction, Tamarix hispida Willd., biologically active substances, hydrolyzable tannins, UV-spectrometry, antidiabetic activity

Abstract

The extractions of biologically active substances from aerial part of Tamarix hispida Willd. over ultrasound have been studied. The results showed that the output of extractive substances using ultrasound was increased to 37.34% under the following conditions: 10% ethyl alcohol in a raw-extractant ratio (1 : 6) for 25 minutes at a 20–25 °С temperature and an ultrasound frequency of 35 kHz. The extraction was compared with maceration by yield and chemical composition. As a result of optimization, the output of components from the raw material is increased by 3–4 times at ultrasound frequency from 20 to 35 kHz and extraction time is significantly reduced from 48 hours to 30 minutes. It was found that the major substances were hydrolyzable tannins, the content of which are 10% (ultrasonic extraction) and 8% (maceration), respectively. Using UV-spectrometry, it was confirmed that the appearance of a characteristic maximum in the spectrum of the substance to be analyzed corresponds to the area of absorption of gallic acid and its derivatives, which indicates the content of these in the structure of hydrolyzable tannins. The substance shown significant antidiabetic activity (in vitro) at IC 50 = 3.94±0.14 μg/ml.

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Author Biographies

Shynar Nurlanovna Zhumagaliyeva, Al-Farabi Kazakh National University

профессор, доктор химических наук

Arailym Amanzholkyzy, Al-Farabi Kazakh National University

докторант

Nurgul Adaybaevna Sultanova, Al-Farabi Kazakh National University

доцент,  доктор химических наук

Zharylkasyn Abduakhitovich Abilov, Al-Farabi Kazakh National University

профессор, доктор химических наук

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Published
2021-09-27
How to Cite
1. Zhumagaliyeva S. N., Amanzholkyzy A., Sultanova N. A., Abilov Z. A. USE OF ULTRASOUND FOR EXTRACTION OF BIOLOGICALLY ACTIVE SUBSTANCES FROM TAMARIX HISPI-DA WILLD. // chemistry of plant raw material, 2021. № 3. P. 283-289. URL: http://journal.asu.ru/cw/article/view/8695.
Issue
No 3 (2021)
Section
Low-molecular weight compounds

Copyright (c) 2021 chemistry of plant raw material

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