THE FIRST DETECTION OF CANNABINOIDS IN SMOKE FROM THE INCENSE OF RHODODENDRON TOMENTOSUM (LEDUM PALUSTRE L.), USED IN THE FOLK SHAMANIC PRACTICE OF THE UDEGE PEOPLE BY HPLC-ESI-MS/MS SPECTROMETRY:

Vasily Ivanovich Dunkay; Mayya Petrovna Razgonova; Alexander Mikhailovich Zakharenko; Alexey Vladimirovich Razgonov; Alexander Mikhailovich Panichev; Kirill Sergeyevich Golokhvast

doi:10.14258/jcprm.20260316678

Vasily Ivanovich Dunkay Siberian Federal Scientific Centre of Agrobiotechnology RAS Email: rarf@yandex.ru
Mayya Petrovna Razgonova N.I. Vavilov All-Russian Institute of Plant Genetic Resources; Far Eastern Federal University https://orcid.org/0000-0002-9732-1649 Email: m.razgonova@vir.nw.ru
Alexander Mikhailovich Zakharenko Siberian Federal Scientific Centre of Agrobiotechnology RAS; Far Eastern Federal University; National Research Tomsk State University Email: zakharenko@sfsca.ru
Alexey Vladimirovich Razgonov N.I. Vavilov All-Russian Institute of Plant Genetic Resources Email: razgonov@dvfu.ru
Alexander Mikhailovich Panichev National Research Tomsk State University Email: m.razgonova@vir.nw.ru
Kirill Sergeyevich Golokhvast Siberian Federal Scientific Centre of Agrobiotechnology RAS; Far Eastern Federal University; National Research Tomsk State University https://orcid.org/0000-0002-4873-2281 Email: golokhvast@sfsca.ru

https://doi.org/10.14258/jcprm.20260316678

Ключевые слова: Ledum palustre, Rhododendron tomentosum, cannabinoids, tandem mass spectrometry, phenolic compounds

Аннотация

Ledum palustre L. has been actively used in ethnomedicine in Mongolia, China and Russian Far East (indigenous peoples: Udege and Evenki) for centuries, as an antioxidant, immunomodulating, anti-inflammatory, vitality-restoring agent. L. palustre contain various phenolic compounds and fatty acids with valuable biological activity. This plant is especially actively used in shamanic and healing practices among the Udege people living in the Primorsky and Khabarovsk Territories, Russia. We used the method of extracting biological substances by incense from the L. palustre using the methods of shamanic practices thanks to the direct participation of the shaman of the Udege people Vasily I. Dunkay. Tandem mass-spectrometry was applied to detect target analytes. 113 different biologically active components have been identified in the L. palustre extracts. For the first time, compounds from the group of cannabinoids were identified in this plant. Also, 74 compounds from other chemical groups were identified for the first time.

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Биографии авторов

Vasily Ivanovich Dunkay, Siberian Federal Scientific Centre of Agrobiotechnology RAS

Researcher

Mayya Petrovna Razgonova, N.I. Vavilov All-Russian Institute of Plant Genetic Resources; Far Eastern Federal University

Chief Researcher, Candidate of Biological Sciences

Alexander Mikhailovich Zakharenko, Siberian Federal Scientific Centre of Agrobiotechnology RAS; Far Eastern Federal University; National Research Tomsk State University

Leading Researcher, Candidate of Chemical Sciences

Alexey Vladimirovich Razgonov, N.I. Vavilov All-Russian Institute of Plant Genetic Resources

Researcher

Alexander Mikhailovich Panichev, National Research Tomsk State University

Chief Researcher, Doctor of Biological Sciences, Professor

Kirill Sergeyevich Golokhvast, Siberian Federal Scientific Centre of Agrobiotechnology RAS; Far Eastern Federal University; National Research Tomsk State University

Director, Doctor of Biological Sciences, Professor of the Russian Academy of Sciences

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