СРАВНИТЕЛЬНОЕ ИЗУЧЕНИЕ ХИМИЧЕСКОГО СОСТАВА ЭФИРНЫХ МАСЕЛ MELILOTUS OFFICINALIS И MELILOTUS ALBUS, ПРОИЗРАСТАЮЩИХ В АСТРАХАНСКОЙ ОБЛАСТИ:

Anatoly Valerievich  Velikorodov; Aleksey Pavlovich  Laktionov; Svyatoslav Borisovich  Nosachev; Lyudmila Viktorovna  Morozova

doi:10.14258/jcprm.20250214516

Anatoly Valerievich Velikorodov Astrakhan Tatishchev State University http://orcid.org/0000-0001-9802-8252 Email: avelikorodov.chem@rambler.ru
Aleksey Pavlovich Laktionov Astrakhan Tatishchev State University Email: alaktionov@list.ru
Svyatoslav Borisovich Nosachev Astrakhan Tatishchev State University Email: sbn86chem@yandex.ru
Lyudmila Viktorovna Morozova Astrakhan Tatishchev State University Email: botanika_shaumyna@list.ru

https://doi.org/10.14258/jcprm.20250214516

Keywords: Melilotus officinalis, Melilotus albus, hydrodistillation, essential oil, coumarin, dihydrocoumarin, carvone hydrate, caryophyllene, actinidin, palmitic acid di-2-ethylhexyl ester, humulene

Abstract

Using the hydrodistillation method, samples of essential oil were obtained from the ground parts of Melilotus officinalis and Melilotus albus, growing wild in the Astrakhan region during the flowering phase. The duration of the steam distillation process was established experimentally based on studying the dynamics of changes in the yield of essential oil over time. The yield of essential oil was determined in % based on the weight of absolutely dry raw materials. The highest yield of essential oil is obtained from plants during the flowering phase (0.8–0.9%). Using gas-liquid chromatography, a quantitative analysis of the main components of the essential oil samples of M. officinalis and M. albus was carried out. The quantitative content of essential oil components was calculated from the areas of gas chromatographic peaks without using correction factors. Qualitative analysis was performed by comparing linear retention indices. The main component of the essential oil of M. officinalis and M. albus is coumarin, the content of which is 86.37 and 80.02%, respectively. In the essential oil of M. albus, the major components are also di-2-ethylhexyl ester of palmitic acid (10.5%), carvone hydrate (1.49%), and humulene (1.10%). Other major components of M. officinalis essential oil besides coumarin are phenylethyl alcohol (3.19%), caryophyllene (2.15%), actinidin (1.39%), and dihydrocoumarin (1.29%).

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Author Biographies

Anatoly Valerievich Velikorodov , Astrakhan Tatishchev State University

Doctor of Chemical Sciences, Professor, Professor of the Department of Fundamental and Applied Chemistry

Aleksey Pavlovich Laktionov , Astrakhan Tatishchev State University

Doctor of Biological Sciences, Associate Professor, Professor of the Department of Fundamental Biology

Svyatoslav Borisovich Nosachev , Astrakhan Tatishchev State University

Candidate of Chemical Sciences, Associate Professor, Associate Professor of the Department of Fundamental and Applied Chemistry

Lyudmila Viktorovna Morozova , Astrakhan Tatishchev State University

Candidate of Biological Sciences, Associate Professor, Associate Professor of the Department of Fundamental Biology

References

Talovina G.V. Rod Melilotus Mill. vo flore Rossii i sopredel'nykh stran: sistematika, geografiya, ekologiya, strategiya sokhraneniya: diss. … kand. biol. nauk. [Genus Melilotus Mill. in the flora of Russia and adjacent countries: systemat-ics, geography, ecology, conservation strategy: diss. … Cand. of Biological Sciences]. St. Petersburg, 2011, 234 p. (in Russ.).

Laktionov A.P. Flora Astrakhanskoy oblasti. [Flora of the Astrakhan Region]. Astrakhan', 2009, 296 p. (in Russ.).

Usmanova N.K., Bobakulov Kh.M., Karimov A.M., Sasmakov S.A., Botirov E.Kh., Azimova Sh.S., Abdullayev N.D. Khimiya rastitel'nogo syr'ya, 2022, no. 1, pp. 161168. https://doi.org/10.14258/jcprm.20220110514. (in Russ.).

Gudzenko A.V., Vinogradov B.A. World Applied Sci. J., 2014, vol. 29, no. 2, pp. 171174. https://doi.org/10.5829/idosi.wasj.2014.29.02.1240.

Yefremov A.A., Zykova I.D., Tselukovskaya M.M. Khimiya rastitel'nogo syr'ya, 2012, no. 3, pp. 111114. (in Russ.).

Zykova I.D., Yefremov A.A. Khimiya rastitel'nogo syr'ya, 2012, no. 4, pp. 109112. (in Russ.).

Quijano-Celis C.E., Pino J.A., Morales G. Journal of Essential Oil-Bearing Plants, 2010, vol. 13, no. 3, pp. 313315. https://doi.org/10.1080/0972060X.2010.10643826.

Usmanova N.Q., Bobakulov K.M., Botirov E.K. SJFSU, 2023, vol. 29, no. 1, pp. 5559. https://doi.org/10.56292/SJFSU/vol29iss1/a117.

Grud'ko I.V., Kovaleva A.M., Kolesnik Ya.S. GISAP: Medical Science, Pharmacology, 2017, no. 14, pp. 3435. (in Russ.).

Ed-Dahmani I., El fadili M., Kandsi F., Conte R., El Atki Y., Kara M., Assouguem A., Touijer H., Lfitat A., Nouioura G., Slighoua M., Ullah R., Al-Tamimi J.H., Taleb M., Abdellaoui A. ACS Omega, 2024, vol. 9, no. 8, pp. 92369246. https://doi.org/10.1021/acsomega.3c08314.

Khan S., Shinwari M.I., Haq A., Ali K.W., Rana T., Badshah M., Khan S.A. Pak. J. Bot., 2018, vol. 50, no. 4, pp. 15911598.

Anwer S., Shamim S., Ahmed S., Hasan M.M., Azhar I. Eur. J. Med. Ser. B, 2015, vol. 3, no. 2, pp. 8085. https://doi.org/10.13187/ejm.s.b.2015.3.80.

Liu Yu.-T., Gong P.-H., Xiao F.-Q., Shao S., Zhao D.-Q., Yan M.-M., Yang X.-W. Molecules, 2018, vol. 23, arti-cle 271. https://doi.org/10.3390/molecules23020271.

Horváth G., Csikós E., Andres E.V., Bencsik T., Tokátsy A., Gulyás-Fekete G., Turcsi E., DeliJ., Szȍke È., Ka-mény Á., Payrits M., Szente L., Kocsis M., Molnár P., Helyes Z. Molecules, 2021, vol. 26, article 503. https://doi.org/10.3390/molecules26020503.

Pleşca-Manea L., Pârvu A.E., Pârvu M., Taamaş M., Buia R., Puia M. Phytotherapy Research, 2002, vol. 16, no. 4, pp. 316319. https://doi.org/10.1002/ptr.875.

Sheikh N.A., Desai T.R., Patel R.D. Pharmacogn. J., 2016, vol. 8, no. 3, pp. 239242. https://doi.org/10.5530/pj.2016.3.11.

Al-Snafi A.E. IOSR Journal of pharmacy, 2020, vol. 10, no. 1, pp. 2326.

Pravila sbora i sushki lekarstvennykh rasteniy. [Rules for collecting and drying medicinal plants]. Moscow, 1985, 321 p. (in Russ.).

Tkachev A.V. Issledovaniye letuchikh veshchestv rasteniy. [Study of plant volatile substances]. Novosibirsk, 2008, 969 p. (in Russ.).

Velikorodov A.V., Kovalev V.B., Tyrkov A.G., Degtyarev O.V. Khimiya rastitel'nogo syr'ya, 2010, no. 2, pp. 143146. (in Russ.).

Velikorodov A.V., Pilipenko V.N., Pilipenko T.A., Tyrkov A.G. Khimiya rastitel'nogo syr'ya, 2017, no. 4, pp. 117120. https://doi.org/10.14258/jcprm.2017042041. (in Russ.).

Zykova I.D., Yefremov A.A. Sibirskiy meditsinskiy zhurnal, 2013, no. 5, pp. 112114. (in Russ.).

Attobrakh N.K., Khusnetdinova L.Z., Dubrovnaya S.A., Akulov A.N. AgroEkoInfo, 2020, no. 3. URL: http://agroecoinfo.narod.ru/journal/STATYI/2020/3/st_304.pdf. (in Russ.).

Pan Y., Liu T., Wang X., Sun J. J. Enzyme Inhib. Med. Chem., 2022, vol. 37, no. 1, pp. 616628. https://doi.org/10.1080/14756366.2021.2024526.

Bhattarai N., Kumbhar A.A., Pokharel Y.R., Yadav P.N. Mini-Rev. Med. Chem., 2021, vol. 21, no. 19, pp. 29963029. https://doi.org/10.2174/1389557521666210405160323.

Zhang J., Di H., Luo K., Jahufer Z., Wu F., Duan Z., Stewart A., Yan Z., Wang Y. Molecules, 2018, vol. 23, no. 4, ar-ticle 810. https://doi.org/10.3390/molecules23040810.