LIPOPHILIC COMPOUNDS OF THE AERIAL PART OF GOLDEN DOCK (RUMEX MARITIMUS L., POLYGONACEAE)
UDC 543.544:[582.657.2+615.322]
Abstract
Plant lipophilic compounds, which include carotenoids, chlorophylls, fat-soluble vitamins, have a number of important pharmacological properties: anti-inflammatory, wound healing, antioxidant, antibacterial, etc. Lipophilic substances composition of golden dock (Rumex maritimus L.), a plant of the Polygonaceae family that is promising for application in medical practice, is little studied. The aim of the study was to identify and quantify lipophilic substances contained in the aerial organs of R. maritimus. Using TLC and HPLC methods, the carotenoids β-carotene, lutein, zeaxanthin, as well as vitamins phylloquinone and α-tocopherol were detected in the plant. Total carotenoid content in the aerial part was 5.06±0.04 mg %, which is comparable to such pharmacopoeial raw materials as rowan fruits (Sorbi aucupariae fructus). The high content of phylloquinone was found both in the plant’s entire aerial part (up to 1.90 mg %), in leaves (up to 4.87 mg%) and fruits (up to 2.07 mg%), which allows us to consider the plant under study as a source of vitamin K1. Based on scientific literature suggesting the notable wound-healing properties of carotenoids and phylloquinone, as well as their positive effects on the visual system, we propose to use the R. maritimus herb as an external wound-healing agent and as a potential treatment and preventive measure for visual organ disorders.
Downloads
References
Khasanova S.R., Kudashkina N.V., Gusakova V.A., Zhalalova N.K. Khimiya rastitel'nogo syr'ya, 2021, no. 4, pp. 373–380. https://doi.org/10.14258/jcprm.2021048804. (in Russ.).
Sannikova Ye.G., Kompantseva Ye.V., Popova O.I., Ayrapetova A.Yu. Khimiya rastitel'nogo syr'ya, 2019, no. 2, pp. 119–127. https://doi.org/10.14258/jcprm.2019024077. (in Russ.).
Lozovitskiy D.A. Nauchnyye rezul'taty biomeditsinskikh issledovaniy, 2017, vol. 3, no. 1, pp. 56–62. https://doi.org/10.18413/2313-8955-2017-3-1-56-62. (in Russ.).
Vitale S., Colanero S., Placidi M., Di Emidio G., Tatone C., Amicarelli F., D'Alessandro A.M. Molecules, 2022, vol. 27, no. 11, 3566. https://doi.org/10.3390/molecules27113566.
Johra F.T., Bepari A.K., Bristy A.T., Reza H.M. Antioxidants, 2020, vol. 9, no. 11, 1046. https://doi.org/10.3390/antiox9111046.
Nolan J.M., Mulcahy R., Power R., Moran R., Howard A.N. J. Alzheimers Dis., 2018, vol. 64, no. 2, pp. 367–378. https://doi.org/10.3233/JAD-180160.
Fiedor J., Burda K. Nutrients, 2014, vol. 6, no. 2, pp. 466–488. https://doi.org/10.3390/nu6020466.
Trineyeva O.V., Rudaya M.A., Slivkin A.I. Vestnik VGU. Seriya: Khimiya. Biologiya. Farmatsiya, 2021, no. 4, pp. 126–131. (in Russ.).
Shea M.K., Booth S.L. Advances in Nutrition, 2022, vol. 13, no. 1, pp. 350–351. https://doi.org/10.1093/advances/nmab133.
Yang H.Y., Dong S.S., Zhang C.H., Wu W.L., Lyu L.F., Li W.L. Russ. J. Plant. Physiol., 2020, vol. 67, pp. 76–84. https://doi.org/10.1134/S1021443720010252.
Ravisankar P., Reddy A., Nagalakshmi B., Koushik O., Kumar B.V., Anvith P.S. IOSR Journal of Pharmacy, 2015, vol. 5, no. 11, pp. 12–28.
Petkova N.I., Petrova K.B., Bliznakova M.I., Paskalev D.N., Galunska B.T. Nefrologiya, 2018, vol. 22, no. 1, pp. 29–37. https://doi.org/10.24884/1561-6274-2018-22-1-29-37. (in Russ.).
Hemmati A.A., Houshmand G., Ghorbanzadeh B., Nemati M., Behmanesh M.A. Indian J. Pharmacol., 2014, vol. 46, no. 4, pp. 409–412. https://doi.org/10.4103/0253-7613.135953.
Pazyar N., Houshmand G., Yaghoobi R., Hemmati A.A., Zeineli Z., Ghorbanzadeh B. Indian J. Pharmacol., 2019, vol. 51, no. 2, pp. 88–92. https://doi.org/10.4103/ijp.IJP_183_18.
Markiewicz A., Tyszczuk B., Pasikowska M., Zielinski K., Polguj A., Budzisz E. Journal of Clinical & Experimental Dermatology Research, 2018, vol. 9, no. 4, 1000455. https://doi.org/10.4172/2155-9554.1000455.
Camacho-Barcia M.L., Bulló M., Garcia-Gavilán J.F., Ruiz-Canela M., Corella D., Estruch R., Fitó M., García-Layana A., Arós F., Fiol M., Lapetra J., Serra-Majem L., Pintó X., García-Arellano A., Vinyoles E., Sorli J.V., Salas-Salvadó J. JAMA Ophthalmol., 2017, vol. 135, no. 6, pp. 657–661. https://doi.org/10.1001/jamaophthalmol.2017.1076.
Mong M.A. Nutrients, 2023, vol. 15, no. 8, 1948. https://doi.org/10.3390/nu15081948.
Luksha E.A., Pogodin I.S., Ivanova E.V. Butlerov communications, 2015, vol. 41, no. 3, pp. 103-108. (in Russ.).
Podgurskaya V.V., Luksha E.A., Gushchina E.S., Savchenko I.A., Korneeva I.N., Kalinkina G.I. Khimiya Ras-titel'nogo Syr'ya, 2021, no. 2, pp. 59–78. DOI: 10.14258/jcpim.2021027498. (in Russ.).
Hinna H., Abdullah S.T., Ansari S.H., Alam M.S. Hamdard Medicus, 2007, vol. 50, no. 3, pp. 31–33.
Uddin K., Rahman A., Islam A. International Journal of Advanced Research, 2014, vol. 2, no. 11, pp. 459–469.
Hossain M.S., Rashid A.H.M.A., Rahman M.M., Sadhu S.K. Journal of Applied Pharmaceutical Science, 2015, vol. 5, no. 3, pp. 056–060. https://doi.org/10.7324/JAPS.2015.510.S10.
Vasas A., Orbán-Gyapai O., Hohmann J. Journal of ethnopharmacology, 2015, vol. 175, pp. 198–228. https://doi.org/10.1016/j.jep.2015.09.001.
Topno S.C., Sinha M.R. Journal of Pharmacognosy and Phytochemistry, 2018, vol. 7, no. 1, pp. 371–376.
Podgurskaya V.V., Luksha E.A., Savchenko I.A., Korneeva I.N., Ivanova E.V., Kalinichenko A.M. Journal of Siberi-an Medical Sciences, 2022, vol. 6, no. 1, pp. 38–45. DOI: 10.31549/2542-1174-2022-6-1-38-45. (in Russ.).
Agarwal J.S., Rastogi R.P., Srivastava O.P. Current Science, 1976, vol. 45, no. 17, pp. 619–620.
Alam M.K., Rana Z.H., Kabir N., Begum P., Kawsar M., Khatun M., Ahsan M., Islam S.N. Current Nutrition & Food Science, 2020, vol. 16, no. 7, pp. 1088–1097. https://doi.org/10.2174/1573401315666191209095515.
Trineyeva O.V., Voropayeva S.V., Slivkin A.I. Sorbtsionnyye i khromatograficheskiye protsessy, 2013, vol. 13, no. 2, pp. 213–219. (in Russ.).
Yusprianto M., Zaharah T.A., Silalahi I.H. Jurnal Kimia Sains dan Aplikasi, 2021, vol. 24, no. 4, pp. 126–135. https://doi.org/10.14710/jksa.24.4.126-135.
Luksha E.A., Pogodin I.S., Kalinkina G.I., Kolomiets N.E., Velichko G.N. Modern problems of science and education, 2014, no. 3, 736. URL: https://science-education.ru/ru/article/view?id=13736 (accessed: 13.02.2024). (in Russ.).
Sausserde R., Kampuss K. Proceedings of the 9th Baltic Conference on Food Science and Technology “Food for Con-sumer Well-Being”. Jelgava, 2014, pp. 13–18.
Pechinskiy S.V., Kuregyan A.G., Zilfikarov I.N. Aktual'nyye problemy meditsiny, 2013, vol. 22, no. 11 (154), pp. 26–31. (in Russ.).
Skrotskaya O.V., Punegov V.V. Samarskiy nauchnyy vestnik, 2021, vol. 10, no. 3, pp. 112–116. https://doi.org/10.17816/snv2021103116. (in Russ.).
Zhbanova Ye.V., Chizhkova M.B. Izbrannyye voprosy sovremennoy nauki: monografiya. Chast' XXIV. [Selected is-sues of modern science: monograph. Part XXIV]. Moscow, 2017, 70 p. (in Russ.).
Halder M., Petsophonsakul P., Akbulut A.C., Pavlic A., Bohan F., Anderson E., Maresz K., Kramann R., Schurgers L. International journal of molecular sciences, 2019, vol. 20, no. 4, 896. https://doi.org/10.3390/ijms20040896.
Copyright (c) 2025 Chemistry of plant raw material

This work is licensed under a Creative Commons Attribution 4.0 International License.

This work is licensed under a Creative Commons Attribution 4.0 International License.
The authors, which are published in this journal, agree to the following conditions:
1. Authors retain the copyright to the work and transfer to the journal the right of the first publication along with the work, at the same time licensing it under the terms of the Creative Commons Attribution License, which allows others to distribute this work with the obligatory indication of the authorship of this work and a link to the original publication in this journal .
2. The authors retain the right to enter into separate, additional contractual agreements for the non-exclusive distribution of the version of the work published by this journal (for example, to place it in the university depository or to publish it in a book), with reference to the original publication in this journal.
3. Authors are allowed to post their work on the Internet (for example, in a university repository or on their personal website) before and during the review process of this journal, as this may lead to a productive discussion, as well as more links to this published work.







