PHYTOCHEMICAL STUDY OF CERTAIN WESTERN SIBERIAN CINQUEFOIL SPECIES

UDC 582.711꞉322.192

  • Tatyana Mikhailovna Shaldaeva Central Siberian Botanical Garden SB RAS Email: tshaldaeva@yandex.ru
  • Elena Petrovna Khramova Central Siberian Botanical Garden SB RAS Email: elenakhramova2023@yandex.ru
Keywords: Potentilla, phenolic compounds, antiradical activity

Abstract

The total content of phenolic compounds (according to Folinа-Cecalteu), flavonols, catechins, tannins, phenolic acids, as well as saponins was studied and the antiradical activity in extracts from leaves and inflorescences of eight representatives of the genus Potentilla (Rosaceae) - Potentilla supine, P. argentea, P. anserina, P. bifurcate, P. humifusa, P. longifolia, P. multifida, Р. fruticosa, living in Western Siberia. It has been shown that depending on the species, plant organ and habitat, biologically active compounds are synthesized in different ways. According to the higher content of flavonols, tannins and catechins, leaves and inflorescences are distinguished P. argentea, P. anserina, P. bifurcate и Р. fruticosa. Flavonol content in the leaves of these species varies from 5.49% and in inflorescences to 12.33%. By catechol content Р. f ruticosa (up to 1.5%). There was a significant accumulation of tannins in the leaves and inflorescences of the studied plants up to 3.0% in the leaves and up to 3.32% in the inflorescences P. argentea. The least flavonols and tannins accumulate in the leaves of P. multifida compared to other species. A high saponin content was found in leaves of the species P. anserine (34.94%) and P. fruticosa (21.61%) and in inflorescences of P. argentea (26.37%) and P. anserine (26.24%). The minimum value of saponins in the leaves of P. anserine (6.19%) and in the inflorescences of P. multifida (2.97%). Extracts from P. bifurcate leaves (IC50 = 0.37 mg/ml) and inflorescences (IC50 = 0.30 mg/ml) showed higher antiradical activity. Extracts from P. anserine leaves (IC50 = 2.55 mg/ml) and P. argentea inflorescences (IC50 = 3.59 mg/ml) are less effective.

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Author Biographies

Tatyana Mikhailovna Shaldaeva , Central Siberian Botanical Garden SB RAS

candidate of biological sciences, researcher at the laboratory of phytochemistry

Elena Petrovna Khramova , Central Siberian Botanical Garden SB RAS

Doctor of Biological Sciences, Head of the Phytochemistry Laboratory

References

Kechaykin A.A. Rod Potentilla sensu stricto (Rosaceae) vo flore Altayskoy gornoy strany (AGS): avtoref. diss. ... kand. biol. nauk. [Genus Potentilla sensu stricto (Rosaceae) in the flora of the Altai mountain country (AGS): author's ab-stract. diss. ... candidate of biological sciences]. Novosibirsk, 2016, 17 p. (in Russ.).

Tomczyk M., Paduch R., Wiater A., Pleszczyńska M. Kandefer-Szerszeń M., Szczodrak J. Acta poloniae pharmaceuti-ca, 2013, vol. 70, no. 3, pp. 523–531.

Paduch R., Wiater A., Locatelli M., Pleszczyńska M., Tomczyk M. Current Drug Targets, 2015, vol. 16, pp. 1495–1502. https://doi.org/10.2174/1389450116666141205160444.

Augustynowicz D., Lemieszek M.K., Strawa J.W., Wiater A., Tomczyk M. Int. J. Mol. Sci., 2023, vol. 24, 4836. https://doi.org/10.3390/ijms24054836.

Savel'yeva Ye.Ye., Bulgakova N.A., Lapkina Ye.Z., Chernaya V.V., Kurbatskiy V.I. Razrabotka i registratsiya le-karstvennykh sredstv, 2022, no. 11(4), pp. 20–27. https://doi.org/10.33380/2305-2066-2022-11-4-20-27. (in Russ.).

Augustynowicz D., Latte K.P., Tomczyk M. J. Ethnopharmacol., 2021, vol. 122(2), pр. 184–204. https://doi.org/10.1016/j.jep.2020.113412.

Miliauskas G., van Beek T.A., Venskutonis P.R., Linssen J.P.H., de Waard P., Sudhӧlter E.J. Journal of the Science of Food and Agriculture, 2004, vol. 84, pр. 1997–2009.

Sklyarevskaya N.V., Popov K.V. Farmatsiya, 2013, no. 5, pp. 12–14. (in Russ.).

Romanteyeva Yu.V., Durnova N.A. Byulleten' Botanicheskogo sada Saratovskogo gosuniversiteta, 2015, no. 13, pp. 74–78. (in Russ.).

Bolotova V.Ts., Sklyarevskaya N.V., Popova K.V. Farmatsiya, 2014, no. 6, pp. 56–58. (in Russ.).

Guo T., Qing Wei J., Ping Ma J. Pharmaceutical biology, 2016, vol. 54, no. 5, pp. 807–811. https://doi.org/10.3109/13880209.2015.1080734.

Olennikov D.N., Kashchenko N.I., Chirikova. N.K., Kuz’mina S.S. Molecules, 2015, vol. 20, no. 1, pр. 224–248. https://doi.org/10.3390/molecules20010224.

Khisyamova D.M. Sravnitel'noye farmakognosticheskoye issledovaniye nekotorykh predstaviteley roda Lapchatka (Po-tentilla L.): avtoref. dis. … kand. farm. nauk. [Comparative pharmacognostic study of some representatives of the ge-nus Potentilla L.: author's abstract. dis. … candidate of pharmaceutical sciences]. Samara, 2017, 22 p. (in Russ.).

Zhao Y.-L., Cai G.-M., Hong X., Shan L.-M., Xiao X.-H. Phytomedicine, 2008, vol. 15, no. 4, pp. 253–258. https://doi.org/10.1016/j.phymed.2008.01.00516.

Goryachkina Ye.G. Farmakognosticheskoye issledovaniye nekotorykh predstaviteley roda lapchatka, proizrastayu-shchikh na territorii Vostochnoy Sibiri: avtoref. dis. ... kand. farm. nauk. [Pharmacognostic study of some representa-tives of the genus Potentilla growing in Eastern Siberia: author's abstract. dis. ... candidate of pharmaceutical sciences]. Ufa, 1994, 17 p. (in Russ.).

Khramova Ye.P., Kukushkina T.A., Shaldayeva T.M., Syyeva S.Ya. Khimiya rastitel'nogo syr'ya, 2020, no. 1, pp. 189–197. https://doi.org/10.14258/jcprm.2020015145. (in Russ.).

Yevstropov A.N., Burova L.G., Grek O.R., Zakharova L.N., Volkhonskaya T.A. Byulleten' sibirskoy meditsiny, 2002, no. 4, pp. 27–31. (in Russ.).

Tomczyk M., Paduch R., Wiater A., Pleszczyńska M., Kandefer-szersze M., Szczodrak J. Acta Pol Pharm – Drug Re-search, 2013, vol. 70, pр. 523–531.

Kukushkina T.A., Kostikova V.A., Khramova Ye.P. Khimiya rastitel'nogo syr'ya, 2024, no. 2, pp. 196–206. https://doi.org/10.14258/jcprm.20240212561. (in Russ.).

Gosudarstvennaya farmakopeya RF, 14-ye izd. [State Pharmacopoeia of the Russian Federation, 14th edition]. Mos-cow, 2018, vol. 4, pp. 6081–6083. (in Russ.).

Denisenko T.A., Vishnikin A.B., Tsyganok L.P. Analitika i kontrol', 2015, vol. 19, no. 4, pp. 373–380. https://doi.org/10.15826/analitika.2015.19.4.012. (in Russ.).

Fedoseyeva L.M. Khimiya rastitel'nogo syr'ya, 2005, no. 2, pp. 45–50. (in Russ.).

Pisarev D.I. i dr. Khimiya rastitel'nogo syr'ya, 2009, no. 4, pp. 197–198. (in Russ.).

Tohidi B., Rahimmalek M., Arzani A. Food Chem., 2017, vol. 220, pp. 153–161. https://doi.org/10.1016/j.foodchem.2016.09.203.

Kumarasamy Y., Byres M., Cox P.J., Jaspars M., Nahar L., Sarker S.D. Phytotherapy Research, 2007, vol. 21, nо. 7, pр. 615–621.

Gawron-Gzella A., Witkowska-Banaszczak E., Bylka W., Dudek-Makuch M., Odwrot A., Skrodzka N. Pharmaceuti-cal Chemistry Journal, 2016, vol. 50, no. 4, pp. 244–249. https://doi.org/10.1007/s11094-016-1431-0.

Wang L.-Y., Kou Y.-X., Wu G.-L., Wang Y.-J. Conserv Genet Resour., 2009, vol. 51, pр. 698–706. https://doi.org/10.1111/j.1744-7909.2009.00818.x.

Syrpas M., Subbarayadu K., Kitrytė V., Rimantas P.V. Antioxidants, 2020, vol. 9, 457. https://doi.org/10.3390/antiox9060457.

Podolak I., Galanty A., Sobolewska D. Phytochem Rev., 2010, vol. 9, pp. 425–474. https://doi.org/10.1007/s11101-010-9183-z.

Trineyeva O.V. Razrabotka i registratsiya lekarstvennykh sredstv, 2017, no. 4 (21), pp. 180–197. (in Russ.).

Published
2025-09-30
How to Cite
1. Shaldaeva T. M., Khramova E. P. PHYTOCHEMICAL STUDY OF CERTAIN WESTERN SIBERIAN CINQUEFOIL SPECIES // Chemistry of plant raw material, 2025. № 3. P. 272-282. URL: https://journal.asu.ru/cw/article/view/15272.
Section
Low-molecular weight compounds