PHYTOCHEMICAL STUDY OF CERTAIN WESTERN SIBERIAN CINQUEFOIL SPECIES
UDC 582.711꞉322.192
Abstract
The total content of phenolic compounds (according to Folinа-Cecalteu), flavonols, catechins, tannins, phenolic acids, as well as saponins was studied and the antiradical activity in extracts from leaves and inflorescences of eight representatives of the genus Potentilla (Rosaceae) - Potentilla supine, P. argentea, P. anserina, P. bifurcate, P. humifusa, P. longifolia, P. multifida, Р. fruticosa, living in Western Siberia. It has been shown that depending on the species, plant organ and habitat, biologically active compounds are synthesized in different ways. According to the higher content of flavonols, tannins and catechins, leaves and inflorescences are distinguished P. argentea, P. anserina, P. bifurcate и Р. fruticosa. Flavonol content in the leaves of these species varies from 5.49% and in inflorescences to 12.33%. By catechol content Р. f ruticosa (up to 1.5%). There was a significant accumulation of tannins in the leaves and inflorescences of the studied plants up to 3.0% in the leaves and up to 3.32% in the inflorescences P. argentea. The least flavonols and tannins accumulate in the leaves of P. multifida compared to other species. A high saponin content was found in leaves of the species P. anserine (34.94%) and P. fruticosa (21.61%) and in inflorescences of P. argentea (26.37%) and P. anserine (26.24%). The minimum value of saponins in the leaves of P. anserine (6.19%) and in the inflorescences of P. multifida (2.97%). Extracts from P. bifurcate leaves (IC50 = 0.37 mg/ml) and inflorescences (IC50 = 0.30 mg/ml) showed higher antiradical activity. Extracts from P. anserine leaves (IC50 = 2.55 mg/ml) and P. argentea inflorescences (IC50 = 3.59 mg/ml) are less effective.
Downloads
Metrics
References
Kechaykin A.A. Rod Potentilla sensu stricto (Rosaceae) vo flore Altayskoy gornoy strany (AGS): avtoref. diss. ... kand. biol. nauk. [Genus Potentilla sensu stricto (Rosaceae) in the flora of the Altai mountain country (AGS): author's ab-stract. diss. ... candidate of biological sciences]. Novosibirsk, 2016, 17 p. (in Russ.).
Tomczyk M., Paduch R., Wiater A., Pleszczyńska M. Kandefer-Szerszeń M., Szczodrak J. Acta poloniae pharmaceuti-ca, 2013, vol. 70, no. 3, pp. 523–531.
Paduch R., Wiater A., Locatelli M., Pleszczyńska M., Tomczyk M. Current Drug Targets, 2015, vol. 16, pp. 1495–1502. https://doi.org/10.2174/1389450116666141205160444.
Augustynowicz D., Lemieszek M.K., Strawa J.W., Wiater A., Tomczyk M. Int. J. Mol. Sci., 2023, vol. 24, 4836. https://doi.org/10.3390/ijms24054836.
Savel'yeva Ye.Ye., Bulgakova N.A., Lapkina Ye.Z., Chernaya V.V., Kurbatskiy V.I. Razrabotka i registratsiya le-karstvennykh sredstv, 2022, no. 11(4), pp. 20–27. https://doi.org/10.33380/2305-2066-2022-11-4-20-27. (in Russ.).
Augustynowicz D., Latte K.P., Tomczyk M. J. Ethnopharmacol., 2021, vol. 122(2), pр. 184–204. https://doi.org/10.1016/j.jep.2020.113412.
Miliauskas G., van Beek T.A., Venskutonis P.R., Linssen J.P.H., de Waard P., Sudhӧlter E.J. Journal of the Science of Food and Agriculture, 2004, vol. 84, pр. 1997–2009.
Sklyarevskaya N.V., Popov K.V. Farmatsiya, 2013, no. 5, pp. 12–14. (in Russ.).
Romanteyeva Yu.V., Durnova N.A. Byulleten' Botanicheskogo sada Saratovskogo gosuniversiteta, 2015, no. 13, pp. 74–78. (in Russ.).
Bolotova V.Ts., Sklyarevskaya N.V., Popova K.V. Farmatsiya, 2014, no. 6, pp. 56–58. (in Russ.).
Guo T., Qing Wei J., Ping Ma J. Pharmaceutical biology, 2016, vol. 54, no. 5, pp. 807–811. https://doi.org/10.3109/13880209.2015.1080734.
Olennikov D.N., Kashchenko N.I., Chirikova. N.K., Kuz’mina S.S. Molecules, 2015, vol. 20, no. 1, pр. 224–248. https://doi.org/10.3390/molecules20010224.
Khisyamova D.M. Sravnitel'noye farmakognosticheskoye issledovaniye nekotorykh predstaviteley roda Lapchatka (Po-tentilla L.): avtoref. dis. … kand. farm. nauk. [Comparative pharmacognostic study of some representatives of the ge-nus Potentilla L.: author's abstract. dis. … candidate of pharmaceutical sciences]. Samara, 2017, 22 p. (in Russ.).
Zhao Y.-L., Cai G.-M., Hong X., Shan L.-M., Xiao X.-H. Phytomedicine, 2008, vol. 15, no. 4, pp. 253–258. https://doi.org/10.1016/j.phymed.2008.01.00516.
Goryachkina Ye.G. Farmakognosticheskoye issledovaniye nekotorykh predstaviteley roda lapchatka, proizrastayu-shchikh na territorii Vostochnoy Sibiri: avtoref. dis. ... kand. farm. nauk. [Pharmacognostic study of some representa-tives of the genus Potentilla growing in Eastern Siberia: author's abstract. dis. ... candidate of pharmaceutical sciences]. Ufa, 1994, 17 p. (in Russ.).
Khramova Ye.P., Kukushkina T.A., Shaldayeva T.M., Syyeva S.Ya. Khimiya rastitel'nogo syr'ya, 2020, no. 1, pp. 189–197. https://doi.org/10.14258/jcprm.2020015145. (in Russ.).
Yevstropov A.N., Burova L.G., Grek O.R., Zakharova L.N., Volkhonskaya T.A. Byulleten' sibirskoy meditsiny, 2002, no. 4, pp. 27–31. (in Russ.).
Tomczyk M., Paduch R., Wiater A., Pleszczyńska M., Kandefer-szersze M., Szczodrak J. Acta Pol Pharm – Drug Re-search, 2013, vol. 70, pр. 523–531.
Kukushkina T.A., Kostikova V.A., Khramova Ye.P. Khimiya rastitel'nogo syr'ya, 2024, no. 2, pp. 196–206. https://doi.org/10.14258/jcprm.20240212561. (in Russ.).
Gosudarstvennaya farmakopeya RF, 14-ye izd. [State Pharmacopoeia of the Russian Federation, 14th edition]. Mos-cow, 2018, vol. 4, pp. 6081–6083. (in Russ.).
Denisenko T.A., Vishnikin A.B., Tsyganok L.P. Analitika i kontrol', 2015, vol. 19, no. 4, pp. 373–380. https://doi.org/10.15826/analitika.2015.19.4.012. (in Russ.).
Fedoseyeva L.M. Khimiya rastitel'nogo syr'ya, 2005, no. 2, pp. 45–50. (in Russ.).
Pisarev D.I. i dr. Khimiya rastitel'nogo syr'ya, 2009, no. 4, pp. 197–198. (in Russ.).
Tohidi B., Rahimmalek M., Arzani A. Food Chem., 2017, vol. 220, pp. 153–161. https://doi.org/10.1016/j.foodchem.2016.09.203.
Kumarasamy Y., Byres M., Cox P.J., Jaspars M., Nahar L., Sarker S.D. Phytotherapy Research, 2007, vol. 21, nо. 7, pр. 615–621.
Gawron-Gzella A., Witkowska-Banaszczak E., Bylka W., Dudek-Makuch M., Odwrot A., Skrodzka N. Pharmaceuti-cal Chemistry Journal, 2016, vol. 50, no. 4, pp. 244–249. https://doi.org/10.1007/s11094-016-1431-0.
Wang L.-Y., Kou Y.-X., Wu G.-L., Wang Y.-J. Conserv Genet Resour., 2009, vol. 51, pр. 698–706. https://doi.org/10.1111/j.1744-7909.2009.00818.x.
Syrpas M., Subbarayadu K., Kitrytė V., Rimantas P.V. Antioxidants, 2020, vol. 9, 457. https://doi.org/10.3390/antiox9060457.
Podolak I., Galanty A., Sobolewska D. Phytochem Rev., 2010, vol. 9, pp. 425–474. https://doi.org/10.1007/s11101-010-9183-z.
Trineyeva O.V. Razrabotka i registratsiya lekarstvennykh sredstv, 2017, no. 4 (21), pp. 180–197. (in Russ.).
Copyright (c) 2025 Chemistry of plant raw material

This work is licensed under a Creative Commons Attribution 4.0 International License.

This work is licensed under a Creative Commons Attribution 4.0 International License.
The authors, which are published in this journal, agree to the following conditions:
1. Authors retain the copyright to the work and transfer to the journal the right of the first publication along with the work, at the same time licensing it under the terms of the Creative Commons Attribution License, which allows others to distribute this work with the obligatory indication of the authorship of this work and a link to the original publication in this journal .
2. The authors retain the right to enter into separate, additional contractual agreements for the non-exclusive distribution of the version of the work published by this journal (for example, to place it in the university depository or to publish it in a book), with reference to the original publication in this journal.
3. Authors are allowed to post their work on the Internet (for example, in a university repository or on their personal website) before and during the review process of this journal, as this may lead to a productive discussion, as well as more links to this published work.







