SOME COMPONENTS FROM FLOWERS AND SEEDS OF HELLEBORUS CAUCASICUS A.BR.
Abstract
In present paper we report on results of investigation of the ethyl acetate fractions from Helleborus caucasicus seeds and flowers. By HPLC separation 3 individual compounds (1–3) have been isolated from the ethyl acetate fraction of plant seeds and 3 compounds as well (4–6) have been obtained from similar fraction of flowers. Structures of individual compounds were established by comparison of the physical-chemical and spectral data to the literary resources. 20-hydroxyecdysone and hellebrigenin 3-0-β-D-glucopyranoside (1–2) we had previously isolated from underground parts and leaves of Helleborus caucasicus; 20-hydroxyecdysone 3-0-β-D-glucoside (3) is a novel compound for this species. p-Coumaric and caffeic acids (4,6) are reported here for the first time in Helleborus genus.
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