BIOLOGICALLY ACTIVE SUBSTANCES OF AGASTACHE RUGOSA (LAMIACEAE), INTRODUCED IN WESTERN SIBERIA

UDC 633.88:615.322

  • Natal'ya Eduardovna Kolomiets Siberian State Medical University; Kemerovo State Medical University Email: borkol47@mail.ru
  • Olga Nikolaevna Shplis Siberian State Medical University; National Research Tomsk State University Email: o.shplis@yandex.ru
Keywords: Agastache rugosa, introduction, Western Siberia, phenolcarboxylic acids, essential oil

Abstract

The report presents the results of the study of the chemical composition of of biologically active substances of various parts and organs of Agastache rugosa introduced in Western Siberia. Agastache rugosa were collected by the authors in July-August 2021–2022 in the territories of Tomsk regions. Water and water-alcohol extracts were obtained from raw materials. The studies was conducted using PC, TLC, UV-spectroscopy, titrimetry. The component composition of the essential oil was studied by GLC-MS on the gas chromatograph Agilent 6890 with quadrupole mass spectrometer (HP MSD 5973N). About 50 individual components were found, 30 of them for the first time. Vitamins (ascorbic acid, carotenoids), polysaccharides, phenolic compounds (flavonoids, phenolcarbonic acids, tannins), essential oil were found in all organs of the plant. Saponins are present in flowers and herbs, but not found in fruits. The presence of acacetin, apigenin, quercetin, tilianine, rosemary acid, caffeic acid, chlorogenic acid was found. The difference in the content of biologically active substances in different organs was established. The dominant groups in different parts and organs of the plant are essential oil, phenol carboxylic acids, carotenoids, ascorbic acid. Flavonoids and chlorophyll in all organs of this species belong to the group of minor BAS.

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Author Biographies

Natal'ya Eduardovna Kolomiets, Siberian State Medical University; Kemerovo State Medical University

доктор фармацевтических наук, профессор, профессор кафедры фармацевтического анализа, профессор кафедры фармации

Olga Nikolaevna Shplis, Siberian State Medical University; National Research Tomsk State University

кандидат фармацевтических наук, старший преподаватель кафедры фармацевтического анализа

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Published
2023-06-26
How to Cite
1. Kolomiets N. E., Shplis O. N. BIOLOGICALLY ACTIVE SUBSTANCES OF AGASTACHE RUGOSA (LAMIACEAE), INTRODUCED IN WESTERN SIBERIA // chemistry of plant raw material, 2023. № 2. P. 133-141. URL: http://journal.asu.ru/cw/article/view/11640.
Section
Low-molecular weight compounds