CHROMATOGRAPHIC AND SPECTRAL STUDY OF ARCTIUM LAPPA AND ARCTIUM TOMENTOSUM FRUCTUS CULTIVATED IN ALTAI
UDC 581.192:582.998.2:543.421/424
Abstract
Burdock is an ingredient of official and traditional medicines in different countries, its roots are used for food, biologically active additives, functional nutrition products, fertilizers, etc. A great demand led to the situation when many countries including Russia began the plant’s cultivation. Despite that, the aboveground parts of the plant including its fructus still remain expendable. At the moment, burdock fructus are officially used only in China and Japan. In Russia they are not used and studies of their chemical composition and pharmacological properties are scarce.
The research showed that fructus of Arctium lappa and A. tomentosum cultivated in Altai using by traditional way of growing, and new of agrotechnics of cultivation contain lignans, hydroxycinamic acid, fatty acids and their derivatives, polysaccharides and anthocyanin’s. The use of a new cultivation technology increased the content of lignans and other BAS by 10–25%. Hydroxycinamic acid is one of the dominant substances in fructus by content, therefore it is possible to standardize raw material according to this parameter. The presence of methyl cis-9, cis-15-octadecadienoate and 11-Eicosenoic acid methyl ester in fructushas been discovered for the first time. Ethyl linoleate and methylfolate or methyl cis-9-octadecenoate are found to be dominant components of fatty acids and their derivatives.
Additional studies of chemical composition, pharmacological properties, clinical approbation are needed to obtain evidence of the efficiency of burdock fructus utilization for clinical purposes and prevention.
Downloads
Metrics
References
Arctium. The Plant List. Version 1.1. 2013.
Rastitel'nyye resursy Rossii. Dikorastushchiye tsvetkovyye rasteniya, ikh komponentnyy sostav i biologicheskaya ak-tivnost'. T. 5. Semeystvo Asteraceae (Compositae). Ch. 1. Rody Achillea–Doronicum. [Plant resources of Russia. Wild flowering plants, their component composition and biological activity. Vol. 5. Family Asteraceae (Compositae). Part 1. Genera Achillea–Doronicum]. Moscow, 2012, 320 р. (in Russ.).
Sokolov S.Ya. Spravochnik po lekarstvennym rasteniyam [Handbook of Medicinal Plants]. Moscow, 1990, 464 p. (in Russ.).
Sobolevskaya K.A. et al. Poleznyye rasteniya Zapadnoy Sibiri i perspektivy ikh introduktsii. [Useful plants of Western Siberia and prospects for their introduction]. Novosibirsk, 1972, 58 p. (in Russ.).
Gun G. Asian Journal of Pharmaceutical and Clinical Research, 2019, vol. 12, no. 7, pp. 53–59. DOI: 10.22159/ajpcr.2019.v12i7.33870.
Wang D., Bădărau A.S., Swamy M.K. et al. Front Plant Sci., 2019, vol. 10, article 834. DOI: 10.3389/fpls.2019.00834.
Kolomiets N.E., Boev R.S., Zhalnina L.V. et al. Khimiya Rastitel'nogo Syr'ya, 2021, no. 2, pр. 29–57. DOI: 10.14258/jcprm.2021028315. (in Russ.).
Kolomiets N.E., Korolev S.A., Isaykina N.V. et al. Pharmacogn J., 2021, vol. 13, no. 6, pр. 1734–1745. DOI: 10.5530/pj.2021.13.224.
Adham A.N., Hegazy M.E.F., Naqishbandi A.M., Efferth T. Molecules, 2020, vol. 25, no. 21, article 5016. DOI: 10.3390/molecules25215016.
Kuo D.-H., Hung M.-C., Hung C.-M. et al. Food Chem., 2012, vol. 134, no. 3, pp. 1320–1326. DOI: 10.1016/j.foodchem.2012.03.023.
Ming D.S., Guns E.S., Eberding A., Towers G.H.N. Pharm Biol., 2004, vol. 42, pp. 44–48. DOI: 10.5650/jos.54.589.
Povet'yeva T.N., Pashinskiy V.G., Kanakina T.A. Rastitel'nyye resursy, 1998, no. 34(2), pp. 57–65. DOI: 10.1080/13880200490505474. (in Russ.).
Os'kina O.A., Pashinskii V.G., Kanakina T.A. et al. Eksperimental'naya i klinicheskaya farmakologiya, 1999, no. 62(4), p. 39. (in Russ.).
Zhou X., Zhang H., Ge L., Gong H., Tian S. J. Chem., 2011, vol. 8, pp. 372–377.
Kharlamov I.A., Khazanovich R.L., Khalmatov Kh.Kh. Chem. of Nat. Comp., 1967, vol. 3, no. 5, p. 295. DOI: 10.1155/2011/517681.
Yakhontova L.D., Kibal'chich P.N. Chem. of Nat. Comp., 1971, vol. 7, no. 3, pp. 287–288. DOI: 10.1007/BF00574642.
Ul'chenko N.T., Bekker N.P., Glushenkova A.I. Chem. of Nat. Comp., 2008, vol. 44, no. 2, pp. 147–150. DOI: 10.1007/BF00569000.
Kharlamov I.A., Khazanovich P.L., Khalmatov Kh.Kh. Farmatsiya, 1968, no. 17(3), pp. 45–49. DOI: 10.1007/s10600-008-9002-6. (in Russ.).
Saleh N.A.M., Bohm B.A. Experientia, 1971, vol. 27, no. 12, p. 1494.
Morris L.J., Marshall M.O., Hammond E.W. Lipids, 1968, vol. 3, no. 1, pp. 91–95. DOI: 10.1007/BF02154314.
Tsevegsüren N., Aitzetmüller K., Vosmann K. Lipids, 1999, vol. 34, no. 5, pp. 525–529. DOI: 10.1007/BF02530976.
Ul'chenko N.T., Gigienova E.I., Umarov A.U., Isamukhamedov A.Sh. Chem. of Nat. Comp., 1981, vol. 17, no. 1, pp. 26–30. DOI: 10.1007/s10600-008-9002-6.
Ucciani E., Mallet G., Gamisans J., Gruber M. Grasas y Aceites, 1994, vol. 45, no. 3, pp. 107–112. DOI: 10.3989/gya.1994.v45.i3.981.
Ge L., Liu F., Hu Y., Zhou X. J. of Planar Chromatogr – Modern TLC, 2020, vol. 33(1), pp. 19–26. DOI: 10.1007/s00764-019-00005-z.
Kopyt'ko Ya.F., Kir'yanov A.A., Stikhin Yu.V. Khimiko-farmatsevticheskiy zhurnal, 2003, no. 6, pp. 46–47. (in Russ.).
Ferracane R., Graziani G., Gallo M., Fogliano V., Ritieni A. J. of Pharm. and Biomed. Analysis, 2010, vol. 51, no. 2, pp. 399–404. DOI: 10.1016/j.jpba.2009.03.018.
Liu J., Cai Y.-Z., Wong R.N.S. et al. J. of Agric. and Food Chemistry, 2012, vol. 60, no. 16, pp. 4067–4075. DOI: 10.1021/jf2050697.
He J., Huang X.-Y., Yang Y.-N. et al. J. of Asian Natur. Prod. Research, 2016, vol. 18, no. 5, pp. 423–428. DOI: 10.1080/10286020.2016.1145671.
Kolomiets N.E., Kalinkina G.I., Sapronova N.N. Farmatsiya, 2011, no. 6, pp. 22–24. (in Russ.).
Gosudarstvennaya farmakopeya RF, XIV izd. [State Pharmacopoeia of the Russian Federation, XIV ed.]. Moscow, 2018. URL: http://resource.rucml.ru/feml/pharmacopia/14_4/HTML/index.html. (in Russ.).
Belyakov K.V., Popov D.M. Farmatsiya, 1998, no. 1, pр. 34–36. (in Russ.).
Chan Y.-Sh., Cheng L.-N., Wu J.-H. et al. Inflammopharmacology, 2011, vol. 19, no. 5, pp. 245–254.
Copyright (c) 2024 chemistry of plant raw material
This work is licensed under a Creative Commons Attribution 4.0 International License.
This work is licensed under a Creative Commons Attribution 4.0 International License.
The authors, which are published in this journal, agree to the following conditions:
1. Authors retain the copyright to the work and transfer to the journal the right of the first publication along with the work, at the same time licensing it under the terms of the Creative Commons Attribution License, which allows others to distribute this work with the obligatory indication of the authorship of this work and a link to the original publication in this journal .
2. The authors retain the right to enter into separate, additional contractual agreements for the non-exclusive distribution of the version of the work published by this journal (for example, to place it in the university depository or to publish it in a book), with reference to the original publication in this journal.
3. Authors are allowed to post their work on the Internet (for example, in a university repository or on their personal website) before and during the review process of this journal, as this may lead to a productive discussion, as well as more links to this published work.
