CHANGES IN THE CONTENT OF PHENOLIC COMPOUNDS IN THE ALDER BLACK LEAVES UNDER THE INFLU-ENCE OF VARIOUS FACTORS
Abstract
The quantitative content of ellagic acid and hyperoside in the leaves of Black alder under various conditions of storage were studied. Data about maintenance change of active components in powdered (2000 microns) and leaves of Black alder which were stored at interval of temperature from 20 to 60 °С and humidity of herbal substances from 9 to 25%. The samples were analyzed at 0, 3, 6, 9, 12, 18, 24 and 36 months by high performance liquid chromatography (HPLC). Results of this study indicate that herbal substances are stable at room temperature (20 °C) and low humidity for 36 months. Destructions hyperoside are amplified with increase in temperature of storage and humidity of herbal substances. The maintenance of ellagic acid increases in the first year of storage in several times, and then decreases. The chemical kinetic data of the changes in the content analytical markers used to quantify the markers may be useful for phytopharmaceutical industry to produce efficacious and stable the herbal substances and the medicinal preparations.
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