SUBCRITICAL WATER AS A TOOL FOR OBTAINING PRODUCTS WITH HIGH ANTIOXIDANT ACTIVITY FROM PRODUCTION WASTE ON THE EXAMPLE OF OLIVE LEAVES (OLEA EUROPAEA L.)

UDC 542.06.542.61.542.46.808.542.97.542.93

  • Salima Salimovna Khizrieva Research Institute of Physical and Organic Chemistry, Southern Federal University Email: hizrieva@sfedu.ru
  • Sergey Nikolaevich Borisenko Research Institute of Physical and Organic Chemistry, Southern Federal University https://orcid.org/0000-0001-9966-9529 Email: snborisenko@sfedu.ru
  • Elena Vladimirovna Maksimenko Research Institute of Physical and Organic Chemistry, Southern Federal University Email: maksimenkoev52@mail.ru
  • Galina Vladimirovna Zharkova Research Institute of Physical and Organic Chemistry, Southern Federal University Email: galya.zharkova.1999@mail.ru
  • Nikolay Ivanovich Borisenko Research Institute of Physical and Organic Chemistry, Southern Federal University Email: niborisenko@sfedu.ru
DOI_disc_logo https://doi.org/10.14258/jcprm.20220210519
Keywords: subcritical water, antioxidant activity, European olive (Olea europaea), polyphenols, flavonoids, oleanolic acid, Folin-Chocalteu method, 2,2-diphenyl-1-picrylhydrazyl (DPPH)

Abstract

Recently, “green chemistry” methods have been increasingly used to process agricultural waste in order to obtain products with high added value. In the presented work, the medium of subcritical water (SBW) was used to obtain (in the temperature range from 100 to 220 °C) extracts from the leaves of the olive (LO) of Olea europaea L. enriched with polyphenols and to assess their antioxidant activity (AOA). The use of medium of SBW for extraction processes allows not only to increase the extraction of secondary plant metabolites (SPM) from the plant matrix, but also to achieve a change in the phytochemical profile of extracts obtained in SBW.

The dependence of the content of secondary plant metabolites (the sum of polyphenolic compounds and flavonoids) and AOA of extracts obtained at different temperatures in SBW and traditional aqueous-alcoholic extraction from olive leaves was studied. It was shown that the content of polyphenolic compounds and the AOA activity of the extracts depend on the extraction conditions. It has been demonstrated that the obtained extract from LO in medium of SBW at 220 °C contains the maximum amount of polyphenolic compounds and demonstrates the maximum AOA (EC50=26.9 μg/ml).

The presented results demonstrate the promise of using SBW for obtaining extracts from LO with a high content of polyphenols for the development of pharmaceuticals and food additives with high AOA.

Downloads

Download data is not yet available.

Author Biographies

Salima Salimovna Khizrieva, Research Institute of Physical and Organic Chemistry, Southern Federal University

младший научный сотрудник

Sergey Nikolaevich Borisenko , Research Institute of Physical and Organic Chemistry, Southern Federal University

кандидат химических наук, старший научный сотрудник

Elena Vladimirovna Maksimenko , Research Institute of Physical and Organic Chemistry, Southern Federal University

научный сотрудник

Galina Vladimirovna Zharkova , Research Institute of Physical and Organic Chemistry, Southern Federal University

магистрант

Nikolay Ivanovich Borisenko , Research Institute of Physical and Organic Chemistry, Southern Federal University

доктор химических наук, главный научный сотрудник

References

Şahin S., Elhussein E.A.A. Phytochemistry Reviews, 2018, vol. 17, no. 4, pp. 657–668. DOI: 10.1007/s11101-018-9552-6.

Kontogianni V.G., Gerothanassis I.P. Natural Product Research, 2012, vol. 26, no. 2, pp. 186–189. DOI: 10.1080/14786419.2011.582842.

Ladhari A., Zarrelli A., Ghannem M., Mimoun M.B. Waste and Biomass Valorization, 2021, vol. 12, no. 7, pp. 3657–3669. DOI: 10.1007/s12649-020-01256-2.

Guinda Á., Castellano J.M., Santos-Lozano J.M., Delgado-Hervás T., Gutiérrez-Adánez P., Rada M. LWT-Food Sci-ence and Technology, 2015, vol. 64, no. 1, pp. 431–438. DOI: 10.1016/j.lwt.2015.05.001.

Lee W., Yang E.J., Ku S.K., Song K.S., Bae J.S. Inflammation, 2013, vol. 36, no. 1, pp. 94–102. DOI: 10.1007/s10753-012-9523-9.

Gutiérrez-Rebolledo G.A., Siordia-Reyes A.G., Meckes-Fischer M., Jiménez-Arellanes A. Asian Pacific journal of tropical medicine, 2016, vol. 9, no. 7, pp. 644–651. DOI: 10.1016/j.apjtm.2016.05.015.

Rodrı́guez J.A., Astudillo L., Schmeda-Hirschmann G. Pharmacological Research, 2003, vol. 48, no. 3, pp. 291–294. DOI: 10.1016/S1043-6618(03)00155-5.

Han B., Peng Z. J. Chem. Pharm. Research, 2014, vol. 6, no. 4, pp. 438–443.

Tuncay S., Senol H., Guler E.M., Ocal N., Secen H., Kocyigit A., Topcu G. Medicinal Chemistry, 2018, vol. 14, no. 6, pp. 617–625. DOI: 10.2174/1573406414666180222094544.

Zhu Y.Y., Huang H.Y., Wu Y.L. Molecular Medicine Reports, 2021, vol. 23, no. 6, p. 440. DOI: 10.3892/mmr.2021.12079.

Bai X., Lai T., Zhou T., Li Y., Li X., Zhang H. Molecules, 2018, vol. 23, no. 6, p. 1395. DOI: 10.3390/molecules23061395.

Jesus J.A., Lago J.H.G., Laurenti M.D., Yamamoto E.S., Passero L.F.D. Evidence-Based Complementary and Alter-native Medicine, 2015, vol. 2015, 620472. DOI: 10.1155/2015/620472.

Córdova C., Gutiérrez B., Martínez-García C., Martín R., Gallego-Muñoz P., Hernández M., Nieto M.L. PLoS One, 2014, vol. 9, no. 4, e91282. DOI: 10.1371/journal.pone.0091282.

Chen S., Wen X., Zhang W., Wang C., Liu J., Liu C. The FASEB Journal, 2017, vol. 31, no. 3, pp. 1085–1096. DOI: 10.1096/fj.201601022R.

Vogel P., Machado I.K., Garavaglia J., Zani V.T., de Souza D., Dal Bosco S.M. Nutrición hospitalaria, 2015, vol. 31, no. 3, pp. 1427–1433. DOI: 10.3305/nh.2015.31.3.8400.

Omar S.H., Scott C.J., Hamlin A.S., Obied H.K. Fitoterapia, 2018, vol. 128, pp. 118–129. DOI: 10.1016/j.fitote.2018.05.011.

Maksimenko E.V., Khizrieva S.S., Borisenko S.N., Lekar A.V., Borisenko N.I., Minkin V.I. Russian Journal of Phys-ical Chemistry B, 2021, vol. 15, no. 7, pp. 1196–1199.

Galkin A.A., Lunin V.V. Uspekhi khimii, 2005, vol. 74, no. 1, pp. 24–40. (in Russ.).

Sinev M.Yu., Shapovalova O.V. Sverkhkriticheskiye flyuidy: teoriya i praktika, 2020, vol. 15, no. 3, pp. 87–102. DOI: 10.34984/SCFTP.2020.15.3.010. (in Russ.).

Liang X., Fan Q. Journal of Materials Science and Chemical Engineering, 2013, vol. 1, no. 5, pp. 1–6. DOI: 10.4236/msce.2013.15001.

Vetrova E.V., Maksimenko E.V., Khizrieva S.S., Bugaeva A.F., Borisenko N.I., Minkin V.I. Journal of natural sci-ence, biology, and medicine, 2017, vol. 8, no. 2, pp. 213–215. DOI: 10.4103/0976-9668.210009.

Maksimenko E.V., Lekar A.V., Borisenko S.N., Khizrieva S.S., Vetrova E.V., Borisenko N.I., Minkin V.I. Russian Journal of Physical Chemistry B, 2018, vol. 12, no. 8, pp. 1269–1275. DOI: 10.1134/S1990793118080092.

Lekar A.V., Maksimenko E.V., Borisenko S.N., Khizrieva S.S., Vetrova E.V., Borisenko N.I., Minkin V.I. Russian Journal of Physical Chemistry B, 2019, vol. 13, no. 8, pp. 1273–1278. DOI: 10.1134/S1990793119080049.

Lekar A.V., Maksimenko E.V., Borisenko S.N., Khizrieva S.S., Borisenko N.I., Minkin V.I. Russian Journal of Phys-ical Chemistry B, 2020, vol. 14, no. 7, pp. 1153–1157. DOI: 10.1134/S199079312007012X.

Khizriyeva S.S., Borisenko N.I. Sverkhkriticheskiye flyuidnyye tekhnologii v reshenii ekologicheskikh problem. [Super-critical fluid technologies in solving environmental problems]. Arkhangel'sk, 2020, vol. 1, pp. 22–26. (in Russ.).

Hayashi Y. Chemical science, 2016, vol. 7, no. 2, pp. 866–880. DOI: 10.1039/C5SC02913A.

Tutel'yan V.A., Eller K.I., Aleshko-Ozhevskiy Yu.P. Rukovodstvo po metodam kontrolya kachestva i bezopasno-sti biologicheski aktivnykh dobavok k pishche. [Guidance on methods of quality control and safety of biologically active food additives]. Moscow, 2004, pp. 124–126. (in Russ.).

Makarova N.V., Zyuzina A.V. Izvestiya vysshikh uchebnykh zavedeniy. Pishchevaya tekhnologiya, 2011, vol. 5-6, no. 323-324, pp. 24–25. (in Russ.).

Marchenko M.A., Zilfikarov I.N., Ibragimov T.A., Maleyev A.G. Farmatsiya i farmakologiya, 2017, vol. 5, no. 3, pp. 222–241. DOI: 10.19163 / 2307-9266-2017-5-3-222-241. (in Russ.).

Khasanov V.V., Ryzhova G.L., Mal'tseva Ye.V. Khimiya rastitel'nogo syr'ya, 2004, no. 3, pp. 63–75. (in Russ.).

Khizriyeva S.S., Borisenko S.N., Maksimenko Ye.V., Vetrova Ye.V., Borisenko N.I., Minkin V.I. Khimiya rastitel'nogo syr'ya, 2021, no. 2, pp. 237–246. DOI: 10.14258/jcprm.2021028752. (in Russ.).

Volkov V.A., Pakhomov P.M. Vestnik Tverskogo gosudarstvennogo universiteta. Seriya: Biologiya i ekologiya, 2007, no. 5, pp. 64–67. (in Russ.).

Roche M., Dufour C., Mora N., Dangles O. Organic and biomolecular chemistry, 2005, vol. 3, no. 3, pp. 423–430. DOI: 10.1039/B416101G.

Vetrova E.V., Maksimenko E.V., Borisenko S.N., Lekar A.V., Borisenko N.I., Minkin V.I. Russian Journal of Physi-cal Chemistry B, 2017, vol. 11, no. 7, pp. 1202–1206. DOI: 10.1134/S1990793117070193.

Maksimenko E.V., Lekar A.V., Khizrieva S.S., Borisenko S.N., Vetrova E.V., Borisenko N.I., Minkin V.I. Journal of Natural Science, Biology and Medicine, 2018, vol. 9, no. 2, pp. 278–281. DOI: 10.4103/jnsbm.JNSBM_161_17.

Erdogan I., Bayraktar O., Uslu M.E., Tuncel Ö. Romanian Biotechnological Letters, 2018, vol. 23, no. 6, pp. 14217–14228. DOI: 10.26327/RBL2018.151.

Published
2022-06-10
How to Cite
1. Khizrieva S. S., Borisenko S. N., Maksimenko E. V., Zharkova G. V., Borisenko N. I. SUBCRITICAL WATER AS A TOOL FOR OBTAINING PRODUCTS WITH HIGH ANTIOXIDANT ACTIVITY FROM PRODUCTION WASTE ON THE EXAMPLE OF OLIVE LEAVES (OLEA EUROPAEA L.) // Chemistry of plant raw material, 2022. № 2. P. 137-146. URL: https://journal.asu.ru/cw/article/view/10519.
Issue
No 2 (2022)
Section
Low-molecular weight compounds

Copyright (c) 2022 chemistry of plant raw material

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

The authors, which are published in this journal, agree to the following conditions:

1. Authors retain the copyright to the work and transfer to the journal the right of the first publication along with the work, at the same time licensing it under the terms of the Creative Commons Attribution License, which allows others to distribute this work with the obligatory indication of the authorship of this work and a link to the original publication in this journal .

2. The authors retain the right to enter into separate, additional contractual agreements for the non-exclusive distribution of the version of the work published by this journal (for example, to place it in the university depository or to publish it in a book), with reference to the original publication in this journal.

3. Authors are allowed to post their work on the Internet (for example, in a university repository or on their personal website) before and during the review process of this journal, as this may lead to a productive discussion, as well as more links to this published work.

Crossref
Scopus
Google Scholar
Europe PMC