THE COMPONENT COMPOSITION OF THE TRAGOPOGON ORIENTALIS VOLATILE CONSTITUENTS AND ITS BIOLOGICAL ACTIVITY

  • Yerlan Melsuly Suleimen Institute of Applied Chemistry, L.N. Gumilyov Eurasian National University Email: suleimen_em@enu.kz
  • Gulsana Galimzhankyzy Sissengaliyeva Institute of Applied Chemistry, L.N. Gumilyov Eurasian National University Email: sissengaliyevag@gmail.com
  • Margarita Yulaevna Ishmuratova E.A. Buketov Karaganda State University Email: margarita.ishmur@mail.ru
  • Roza Ilemisovna Jalmakhanbetova Institute of Applied Chemistry, L.N. Gumilyov Eurasian National University; Kazak University of Technology and Business Email: rozadichem@mail.ru
DOI_disc_logo https://doi.org/10.14258/jcprm.2019034859
Keywords: Tragopogon orientalis L., volatile constituents, hydrodistillation method, GC/MS-analysis, component composition, biological activity

Abstract

The purpose of this study is the chemical investigation of the composition of Tragopogon orientalis volatile constituents (VC) and studying of its biological activity.

This article presents the results of research on the study of the chemical composition of species Tragopogon, as well as data of antiradical and cytotoxic activity. To study the dried and crushed aboveground part of the plant (leaves, flowers and stems) was taken. The raw material was collected in the flowering phase, growing in Northern Kazakstan. The VC was isolated from the plant of Tragopogon orientalis by hydrodistillation method on the Clevenger type  apparatus. The chemical composition of the VC was determined by GC/MS.

The cytotoxic activity of the VC was determined by the survival rate of sea shrimp Artemia salina. VC of T. orientalis in all studied concentrations (1–10 mg ml-1) exhibit acute lethal toxicity - all larvae die. Antiradical activity was determined by the method of colorimetry of free radicals (DPPH). The experimental results showed that the VC of T. orientalis at all tested concentrations (0.1–1.0 mg ml-1) exhibit low antiradical activity compared with the butylhydroxyanisole standard drug.

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Author Biographies

Yerlan Melsuly Suleimen, Institute of Applied Chemistry, L.N. Gumilyov Eurasian National University

Candidate of Chem. Sciences, PhD, Director of the Institute of Applied Chemistry, Professor of Chemistry Department of L.N. Gumilev

Margarita Yulaevna Ishmuratova, E.A. Buketov Karaganda State University

Candidate of biological Sciences, Professor of botany Department of Karaganda state University

Roza Ilemisovna Jalmakhanbetova, Institute of Applied Chemistry, L.N. Gumilyov Eurasian National University; Kazak University of Technology and Business

Doctor of Chem. Sciences, Professor of Technology Department of Kazakh University of technology and business

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Published
2019-04-09
How to Cite
1. Suleimen Y. M., Sissengaliyeva G. G., Ishmuratova M. Y., Jalmakhanbetova R. I. THE COMPONENT COMPOSITION OF THE TRAGOPOGON ORIENTALIS VOLATILE CONSTITUENTS AND ITS BIOLOGICAL ACTIVITY // Chemistry of plant raw material, 2019. № 3. P. 103-108. URL: https://journal.asu.ru/cw/article/view/4859.
Issue
No 3 (2019)
Section
Low-molecular weight compounds

Copyright (c) 2019 Khimiia rastitel'nogo syr'ia (Chemistry of plant raw material)

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