EXTRACTION OF FLAVONOIDS FROM THE LEAVES OF THE LITTLEWALE LITHOSPERMUM OFFICINALE L. (BORAGINACEAE) USING MICROWAVE ENERGY
UDC 615.322:621.385.6
Abstract
One of the possible ways to intensify and increase the efficiency of extraction of biologically active substances from plant materials is the use of microwave radiation. This article presents the results of a study of the influence of parameters of the microwave extraction process on the output of flavonoids from the leaves of the littlewale (Lithospermum officinale L.), belonging to the Boraginaceae family. This plant contains isoquercitrin, which is one of the key flavonoids with the property of tissue regeneration. It was shown that the maximum yield of the target components is achieved with a microwave generator power of 100 W and exposure duration of 2.5 min at a field frequency of 2450 MHz (specific energy consumption is 8.4 kWh/kg). This output is comparable with the output when using conventional convection heating. Microwave radiation provides a 16-fold reduction in the duration of extraction of the sum of flavonoids and an increase in the degree of extraction of isoquercitrin by 23%. The action of microwave energy leads to the destruction of plant tissue, which contributes to a more efficient extraction of flavonoids from plant raw materials.
Downloads
Metrics
References
Kukhareva L.V., Titok V.V., Popov Ye.G., Anoshenko Yu.B., Gil' T.V., Kot A.A. Materialy Mezhdunarod. nauch. konf., posvyashch. 85-letiyu Tsentral'nogo botanicheskogo sada NAN Belarusi. [Materials International. scientific. conf., dedicated. 85th anniversary of the Central Botanical Garden of the National Academy of Sciences of Belarus]. Minsk, 2017, pp. 154–158. (in Russ.).
Kurkina A.V. Flavonoidy farmakopeynykh rasteniy: monografiya. [Flavonoids of pharmacopoeial plants: monograph]. Samara, 2012, 290 p. (in Russ.).
Tarakhovskiy Yu.S., Kim Yu.A., Abdrasilov B.S., Muzafarov Ye.N. Flavonoidy: biokhimiya, biofizika, meditsina. [Flavonoids: biochemistry, biophysics, medicine]. Pushchino, 2013, 310 p. (in Russ.).
Brown J.E., Andersen M., Markham K.R. Flavonoids: chemistry, biochemistry and applications, Boca Ratton, 2006, 1197 p.
Zverev Ya.F. Obzory po klinicheskoy i lekarstvennoy terapii, 2017, no. 15/2, pp. 4–11. DOI: 10.17816/RCF1524-11. (in Russ.).
Olennikov D.N., Chirikova N.K., Tsyrenzhapov A.V. Khimiya rastitel'nogo syr'ya, 2020, no. 1, pp. 97–105. DOI: 10.14258/jcprm.2020015223. (in Russ.).
Shedoeva A., Leavesley D., Upton Z., Fan C. Evidence-Based Complementary and Alternative Medicine, 2019, vol. 1, pp. 2–30. DOI: 10.1155/2019/2684108.
Bhatia N., Singh A., Sharma R., Singh A., Soni V., Singh G., Bajaj J., Dhawan R., Singh B. The Journal of Phyto-pharmacology, 2014, vol. 3 (6), pp. 378–383.
Pang Y., Zhang Y., Huang L., Xu L., Wang K., Wang D., Guan L., Zhang Y., Fulai Yu., Chen Z., Xie X. International Journal of Molecular Sciences, 2017, vol. 8, pp. 2766–2778. DOI: 10.3390/IJMS18122766.
Bhatia N., Kaur G., Soni V., Kataria J., Dhawan R.K. Burns & Trauma, 2016, vol. 4, s41038-016-0032-1. DOI: 10.1186/s41038-016-0032-1
Hemmati A., Namjuyan F., Yousefi S., Housmand G., Haghighian H., Rezaei A. World Journal of plastic surgery, 2017, vol. 7, pp. 25–33.
Dreslera S., Szymczakb G., Wojcika M. Рharmaceutical biology, 2017, vol. 55, no. 1, pp. 691–695. DOI: 10.1080/13880209.2016.1265986.
Bachura Yu.M., Dayneko N.M. Botanika. Semennyye rasteniya (chast' 2). [Botany. Seed plants (part 2)]. Gomel', 2017, 40 p. (in Russ.).
Baczyńska B., Lityńska-Zając M. Vegetation History and Archaeobotany, 2005, vol. 14, pp. 77–80. DOI: 10.1007/s00334-004-0054-7
Aliyeva A.M. Vestnik Altayskogo gosudarstvennogo agrarnogo universiteta, 2017, no. 9, pp. 112– 115. (in Russ.).
Amiri Z.M., Tanideh N., Seddighi A., Mokhtari M., Amini M., Partovi A.S., Manafi A., Hashemi S.S., Mehrabani D. Vegetation History and Archaeobotany, 2017, vol. 6, no. 3, pp. 313–318.
Krasnaya kniga Respubliki Belarus' [Red Book of the Republic of Belarus]. URL: http://redbook.minpriroda.gov.by/plantsinfo.html?id=85. (in Russ.).
Petrova N.V., Medvedava N.A., Budantsev A.L., Shavarda A.L. Khimiya rastitel'nogo syr'ya, 2015, no. 1, pp. 211–215. DOI: 10.14258/jcprm.201501538. (in Russ.).
Fes'kova Ye.V., Leont'yev V.N., Ignatovets O.S., Adamtsevich N.Yu., Besarab A.Yu. Trudy BGTU. Ser. 2. Khimicheskiye tekhnologii, biotekhnologii, geoekologiya, 2019, no. 1, pp. 49–53. (in Russ.).
Patent 20120087980A1 (US). 2012.
Adamtsevich N.Yu. Fes'kova Ye.V., Boltovskiy V.S. Trudy BGTU. Ser. 2. Khimicheskiye tekhnologii, biotekhnologii, geoekologiya, 2020, no. 1 (229), pp. 93–97. (in Russ.).
Konichev A.S., Fedorovskiy N.N., Marakhova A.I., Baurin P.V., Yakubovich L.M., Chernikova M.A. Vestnik MGOU. Seriya: yestestvennyye nauki, 2011, no. 3, pp. 49–54. (in Russ.).
Markin V.I., Cheprasova M.Yu., Bazarnova N.G. Khimiya rastitel'nogo syr'ya, 2014, no. 4, pp. 21–42. DOI: 10.14258/jcprm.201404597. (in Russ.).
Boltovskiy V.S. Trudy BGTU. Ser. 2. Khimicheskiye tekhnologii, biotekhnologii, geoekologiya, 2020, no. 1, pp. 82–92. (in Russ.).
Yu J., Lou Q., Zheng X., Cui Z., Fu J. Molecules, 2017, vol. 22, pp. 2216–2232. DOI: 10.3390/molecules22122216.
Copyright (c) 2021 chemistry of plant raw material
This work is licensed under a Creative Commons Attribution 4.0 International License.
This work is licensed under a Creative Commons Attribution 4.0 International License.
The authors, which are published in this journal, agree to the following conditions:
1. Authors retain the copyright to the work and transfer to the journal the right of the first publication along with the work, at the same time licensing it under the terms of the Creative Commons Attribution License, which allows others to distribute this work with the obligatory indication of the authorship of this work and a link to the original publication in this journal .
2. The authors retain the right to enter into separate, additional contractual agreements for the non-exclusive distribution of the version of the work published by this journal (for example, to place it in the university depository or to publish it in a book), with reference to the original publication in this journal.
3. Authors are allowed to post their work on the Internet (for example, in a university repository or on their personal website) before and during the review process of this journal, as this may lead to a productive discussion, as well as more links to this published work.
