OBTAINING PHYTOANTIOXIDANT COMPLEXES FROM BIOMASS OF INDUSTRIAL MICROALGAE SPECIES AND THE PROSPECTS OF THEIR APPLICATION

UDC 663.18

  • Yulia Genrikhovna Bazarnova Peter the Great St. Petersburg Polytechnic University, Higher School of Biotechnology and Food Production Email: j.bazarnowa2012@yandex.ru
  • Alexey Aleksandrovich Balabaev Peter the Great St. Petersburg Polytechnic University, Higher School of Biotechnology and Food Production Email: Balabaev-alexey97@mail.ru
  • Olga Romanovna Levchuk Peter the Great St. Petersburg Polytechnic University, Higher School of Biotechnology and Food Production Email: levchuk.or@edu.spbstu.ru
Keywords: valorization of biomass of phototrophic microalgae, phytoantioxidant complexes, carotenoids, chlorophylls, phenolic compounds, Chlorella, Dunaliella, Nannochloris

Abstract

The article is devoted to the issues of obtaining valuable nutraceuticals from microalgae biomass. Phytoantioxidant complexes with a high content of carotenoids, chlorophylls and phenolic compounds were isolated from the biomass of microalgae Chlorella vulgaris, Dunaliella salina and Nannochloris sp. Methods for cultivating microalgae biomass and extracting phytoantioxidant complexes of carotenoids, chlorophylls and phenolic compounds are presented.

The phytochemical composition of the obtained phytoantioxidant complexes is analyzed, the results of in silico prediction of the biological activity of the identified biomolecules and experimentally obtained values of antioxidant activity using the DPPH method are presented. The carotenoid content in isolated [FAO]cars varies from 24 to 78 μg/g. The content of chlorophylls in the isolated [FAO] chl is 615–1420 μg/g. The content of phenolic compounds in the obtained [FAO]fs is 997–1405 µg/g.

[FAO]car, isolated from D. Salina, can be used as a functional food supplement with moderately high antioxidant activity or in cosmetic SPF products and pharmaceutical substances as a source of carotenoids and provitamin A, which enhance the protective properties of the skin in relation to to UV radiation.

[FAO]chl isolated from Nannochloris sp can be recommended for use as a food coloring for soft drinks and canned sweets, as well as as a component in creams, ointments, and serums intended to accelerate the proliferation and epithelization of skin cells. [FAO]fs, isolated from Ch. vulgaris is recommended for use as a water-soluble functional food additive with high antioxidant activity, as well as a pharmaceutical substance for the production of drugs with antitumor, anti-inflammatory and cardioprotective properties.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Author Biographies

Yulia Genrikhovna Bazarnova, Peter the Great St. Petersburg Polytechnic University, Higher School of Biotechnology and Food Production

Doctor of Technical Sciences, Director

Alexey Aleksandrovich Balabaev, Peter the Great St. Petersburg Polytechnic University, Higher School of Biotechnology and Food Production

graduate student, head of laboratory

Olga Romanovna Levchuk, Peter the Great St. Petersburg Polytechnic University, Higher School of Biotechnology and Food Production

graduate student, engineer

References

Trineyeva O.V. Razrabotka i registratsiya lekarstvennykh sredst, 2017, no. 4, pp. 180–197. (in Russ.).

Yashin A.Ya., Chernousova N.I. Pishchevaya promyshlennost', 2007, no. 5, pp. 28–30. (in Russ.).

Pokorný J. Trends in Food Science & Technology, 1991, vol. 2, pp. 223–227. https://doi.org/10.1016/0924-2244(91)90695-F.

Gollakota K. International Journal of Information Management, 2008, vol. 28, no. 4, pp. 336–341. https://doi.org/10.1016/j.ijinfomgt.2008.04.003.

Ahmadifar M., Esfahani, D.E., Ahmadifar E., Sheikhzadeh N., Mood S.M., Moradi S.Z. Annals of Animal Science, 2024, vol. 23, no. 4, pp. 1159–1167. https://doi.org/10.2478/aoas-2023-0019.

Wu B., Cheng H., Li X., Yang Q., Hao S., Wang C., Sun B. Algal Research, 2024, vol. 79, 103467. https://doi.org/10.1016/j.algal.2024.103467.

Banskota A.H. Sperker S., Stefanova R., McGinn P.J., O’Leary S.J. Journal of Applied Phycology, 2019, vol. 31, pp. 309–318. https://doi.org/10.1007/s10811-018-1523-1.

Li Y., Chen M. Functional Plant Biology, 2015, vol. 42, no. 6, pp. 493–501. https://doi.org/10.1071/FP14350.

Li H.B., Cheng K.W., Wong C.C., Fan K.W., Chen F., Jiang Y. Food Chem, 2007, vol. 102, no. 3, pp. 771–776. https://doi.org/10.1016/j.foodchem.2006.06.022.

Mulders K.J., Lamers P.P., Martens D.E., Wijffels R.H. Journal of phycology, 2014, vol. 50, no. 2, pp. 229–242. https://doi.org/10.1111/jpy.12173.

Viera I., Pérez-Gálvez A., Roca M. Molecules, 2019, vol. 24, no. 1, 154. https://doi.org/10.3390/molecules24010154.

Hernández-Ledesma B., Herrero M. Bioactive Compounds from Marine Foods: Plant and Animal Sources. Madrid, 2013.

Goiris K., Muylaert K., Fraeye I., Foubert I., De Brabanter J., De Cooman L. Journal of applied phycology, 2012, vol. 24, pp. 1477–1486. https://doi.org/10.1007/s10811-012-9804-6.

Landete J.M. Critical Reviews in Food Science and Nutrition, 2013, vol. 53, no. 7, pp. 706–721. https://doi.org/10.1080/10408398.2011.555018.

Safafar H., Van Wagenen J., Møller P., Jacobsen C. Marine drugs, 2015, vol. 13, no. 12, pp. 7339–7356. https://doi.org/10.3390/md13127069.

Manach C., Scalbert A., Morand C., Rémésy C., Jiménez, L. The American journal of clinical nutrition, 2004, vol. 79, no. 5, pp. 727–747. https://doi.org/10.1093/ajcn/79.5.727.

Cheynier V., Comte G., Davies K.M., Lattanzio V., Martens S. Plant physiology and biochemistry, 2013, vol. 72, pp. 1–20. https://doi.org/10.1016/j.plaphy.2013.05.009.

Shen N., Wang T., Gan Q., Liu S., Wang L., Jin B. Food Chemistry, 2022, vol. 383, 132531. https://doi.org/10.1016/j.foodchem.2022.132531.

Marinoa T., Iovinea A., Casellab P., Martinoc M., Chianesea S., Laroccac V., Molino A. Chem. Eng., 2020, vol. 79, pp. 271–276. https://doi.org/10.3303/CET2079046.

Barkallah M., Dammak M., Louati I., Hentati F., Hadrich B., Mechichi T., Abdelkafi S. Lwt, 2017, vol. 84, pp. 323–330. https://doi.org/10.1016/j.lwt.2017.05.071.

Fradinho P., Niccolai A., Soares R., Rodolfi L., Biondi N., Tredici M.R., Raymundo A. Algal Research, 2020, vol. 45, 101743. https://doi.org/10.1016/j.algal.2019.101743.

Trukhina Ye.V., Bazarnova Yu.G., Aronova Ye.B. XXI vek: itogi proshlogo i problemy nastoyashchego plyus, 2019, vol. 8, no. 4, pp. 153–159. (in Russ.).

Cho S.H., Ji S.C., Hur S.B., Bae J., Park I.S., Song Y.C. Fisheries Science, 2007, vol. 73, pp. 1050–1056.

Pisal D.S., Lele S.S. Indian Journal of Biotechnology, 2005, vol. 4, pp. 476–483.

Borovkov A.B., Gudvilovich I.N. Voprosy sovremennoy al'gologii, 2017, no. 1, p. 5. (in Russ.).

Paulenco A., Vintila A.C.N., Vlaicu A., Ciltea-Udrescu M., Galan A.M. Microorganisms, 2023, vol. 11, no. 6, 1469 https://doi.org/10.3390/microorganisms11061469.

Abdulagatov I.M. Alkhasov A.B., Dogeyev G.D., Tumalayev N.R., Aliyev R.M., Badavov G.B., Salikhova A.S. Yug Rossii: ekologiya, razvitiye, 2018, no. 1, pp. 166–183. https://doi.org/10.18470/1992-1098-2018-1-166-183. (in Russ.).

Bazarnova Yu.G., Balabayev A.A., Medvedeva A.O., Chernikova D.A., Vorob'yev K.V. Butlerovskiye soobshcheniya, 2023, vol. 73, no. 1, pp. 92–100. https://doi.org/10.37952/ROI-jbc-01/23-73-1-92. (in Russ.).

Xi Y., Zhang J., Kong F., Che J., Chi Z. Bioresources and Bioprocessing, 2022, vol. 9, no. 1, 4. https://doi.org/10.1186/s40643-022-00495-6.

Dahmen-Ben Moussa I., Masmoudi M.A., Choura S., Chamkha M., Sayadi S. Biomass Conversion and Biorefinery, 2021, pp. 1–14. https://doi.org/10.1007/s13399-021-01850-x.

Chang C.C., Yang M.H., Wen H.M., Chern J.C. Journal of food and drug analysis. 2002, vol. 10, no. 3. https://doi.org/10.38212/2224-6614.2748.

Kuregyan A.G. Sovremennyye problemy nauki i obrazovaniya, 2015, no. 2-2, p. 464. (in Russ.).

Kuregyan A.G. Sovremennyye problemy nauki i obrazovaniya, 2015, no. 1-2, p. 231. (in Russ.).

Zagoskina N.V., Sinetova M.A., Lapshin P.V., Los' D.A. Khimiya rastitel'nogo syr'ya, 2024, no. 1, pp. 177–185. https://doi.org/10.14258/jcprm.20240112643. (in Russ.).

Sergunova Ye.V. Izucheniye sostava biologicheski aktivnykh veshchestv lekarstvennogo rasti-tel'nogo syr'ya razlich-nykh sposobov konservatsii i lekarstvennykh preparatov na yego osnove: diss. … dokt. farm. nauk. [Study of the com-position of biologically active substances of medicinal plant raw materials of various preservation methods and medici-nal products based on them: diss. ... Doctor of Pharmaceutical Sciences]. Moscow, 2016, 246 p. (in Russ.).

Trineyeva O.V., Voropayeva S.V., Slivkin A.I. Sorbtsionnyye i khromatograficheskiye protsessy, 2013, vol. 13, no. 2. (in Russ.).

PASS Online. URL: http://www.way2drug.com/passonline.

Gulcin İ., Alwasel S.H. Processes, 2023, vol. 11, no. 8, 2248. https://doi.org/10.3390/pr11082248.

Zhgunov I.S., Krasnoshtanova A.A. Prioritetnyye napravleniya nauchnykh issledovaniy. Analiz, upravleniye, perspek-tivy. 2023, pp. 18–25. (in Russ.).

Haoujar I., Cacciola F., Abrini J., Mangraviti D., Giuffrida D., Oulad El Majdoub Y., Skali Senhaji N. Molecules, 2019, vol. 24, no. 22, 4037. https://doi.org/10.21608/ejabf.2022.249822.

Strakh Ya.L., Ignatovets O.S. Khimiya rastitel'nogo syr'ya, 2021, no. 4, pp. 319–325. https://doi.org/10.14258/jcprm.2021049305. (in Russ.).

Pilipenko T.V., Sukhenko L.T., Yegorov M.A., Astaf'yeva O.V., Pilipenko V.N. Mezhdunarodnyy zhurnal priklad-nykh i fundamental'nykh issledovaniy, 2017, no. 2-2, pp. 218–221. (in Russ.).

Published
2025-11-30
How to Cite
1. Bazarnova Y. G., Balabaev A. A., Levchuk O. R. OBTAINING PHYTOANTIOXIDANT COMPLEXES FROM BIOMASS OF INDUSTRIAL MICROALGAE SPECIES AND THE PROSPECTS OF THEIR APPLICATION // Chemistry of plant raw material, 2025. № 4. P. Online First. URL: https://journal.asu.ru/cw/article/view/15966.
Section
Low-molecular weight compounds